response to organic cyclic compound - Ontology Report

acetoacetyl-CoA synthetase

NCBI chr11:120,422,138...120,502,200
Ensembl chr11:120,422,232...120,502,271

aralkylamine N-acetyltransferase

NCBI chr16:45,206,233...45,215,761
Ensembl chr16:45,206,377...45,207,591

ATP binding cassette subfamily B member 1

1,3,8-Trihydroxy-6-methylanthaquinone (emodin)

PMID:19549930

RGD:2315566

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

ABCB11

ATP binding cassette subfamily B member 11

NCBI chr10:54,458,283...54,575,943
Ensembl chr10:54,459,377...54,575,059

ATP binding cassette subfamily C member 2

methotrexate

NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265

ABCC3

ATP binding cassette subfamily C member 3

NCBI chr16:42,646,316...42,703,124
Ensembl chr16:42,646,812...42,702,852

ABCC4

ATP binding cassette subfamily C member 4 (PEL blood group)

NCBI chr 3:73,821,887...74,106,617
Ensembl chr 3:73,821,134...74,106,579

ABCD3

ATP binding cassette subfamily D member 3

NCBI chr20:38,750,147...38,846,011
Ensembl chr20:38,748,787...38,845,989

ACACA

acetyl-CoA carboxylase alpha

NCBI chr16:30,374,166...30,704,635
Ensembl chr16:30,452,343...30,705,004

ACACB

acetyl-CoA carboxylase beta

NCBI chr11:104,325,250...104,488,567
Ensembl chr11:104,349,573...104,488,003

ACAN

aggrecan

antiandrogen flutamide

PMID:18279833

RGD:2315827

NCBI chr29:7,345,350...7,416,951

ACAT1

acetyl-CoA acetyltransferase 1

peroxisome proliferator di(2-ethylhexyl)phthalate (DEHP)

PMID:6489337

RGD:2326103

NCBI chr 1:99,552,760...99,580,079
Ensembl chr 1:99,552,838...99,579,914

ACP5

acid phosphatase 5, tartrate resistant

dioxin TCDD
streptozotocin

PMID:19264158 PMID:20818503

RGD:151667419 RGD:2315905

NCBI chr 6:10,488,572...10,493,508
Ensembl chr 6:10,488,460...10,491,519

ACSL1

acyl-CoA synthetase long chain family member 1

NCBI chr 7:130,712,633...130,783,360
Ensembl chr 7:130,712,308...130,763,756

ACSL3

acyl-CoA synthetase long chain family member 3

isoflavones

NCBI chr10:108,787,341...108,867,523
Ensembl chr10:108,787,061...108,869,042

ACVR1C

activin A receptor type 1C

Kainic acid, pilocarpine

PMID:8934566

RGD:2306243

NCBI chr10:42,935,085...43,030,581
Ensembl chr10:42,942,284...42,994,488

aryl hydrocarbon receptor

7,12-Dimethylbenz(a)anthracene
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

PMID:18059014 PMID:20403408

RGD:2325667 RGD:2325672

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

ALAD

aminolevulinate dehydratase

gossypin; in lead-treated rats

PMID:19647414

RGD:4144142

NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845

5'-aminolevulinate synthase 1

dioxin

NCBI chr22:13,558,011...13,573,740
Ensembl chr22:13,559,180...13,575,869

ALDH1A1

aldehyde dehydrogenase 1 family member A1

diethylstilbestrol

NCBI chr12:83,949,529...84,092,452
Ensembl chr12:83,949,399...84,009,003

aldehyde dehydrogenase 2 family member

protein:altered expression:liver (rat)

PMID:29589772

RGD:14975297

NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374

ALDH3A1

aldehyde dehydrogenase 3 family member A1

benzo[a]pyrene

PMID:12604189 PMID:18203689

RGD:2300310 RGD:2300312

NCBI chr16:18,302,145...18,312,768
Ensembl chr16:18,302,142...18,312,756

ALDOB

aldolase, fructose-bisphosphate B

polychlorinated biphenyl

PMID:9020521

RGD:1599070

NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258

ALDOC

aldolase, fructose-bisphosphate C

NCBI chr16:22,342,750...22,346,811
Ensembl chr16:22,341,318...22,346,620

alkaline phosphatase, biomineralization associated

streptozotocin

NCBI chr20:111,055,583...111,124,143
Ensembl chr20:111,055,558...111,081,850

AMH

anti-Mullerian hormone

methoxychlor
methyl p-hydroxybenzoate, propyl p-hydroxybenziate, butyl p-hydroxybenzoate
propylparaben, butylparaben

PMID:17170213 PMID:22777679 PMID:28208728

RGD:151893504 RGD:151893505 RGD:2315642

NCBI chr 6:2,047,756...2,051,073
Ensembl chr 6:2,048,319...2,050,958

angiopoietin 2

atorvastatin

NCBI chr 8:6,283,619...6,345,320
Ensembl chr 8:6,280,584...6,344,729

annexin A1

kainic acid

NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562

annexin A7

NCBI chr 9:57,863,482...57,900,972
Ensembl chr 9:57,863,546...57,900,324

amphiregulin

NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162

ASNS

asparagine synthetase (glutamine-hydrolyzing)

methotrexate

NCBI chr21:51,244,514...51,264,694
Ensembl chr21:51,247,742...51,265,241

ATF1

activating transcription factor 1

red wine polyphenols

NCBI chr11:46,992,068...47,049,142
Ensembl chr11:47,003,621...47,049,381

ATF2

activating transcription factor 2

involved_in

(PMID:18227516)

PMID:18227516

NCBI chr10:60,644,623...60,734,465
Ensembl chr10:60,644,635...60,734,475

ATP12A

ATPase H+/K+ transporting non-gastric alpha2 subunit

NCBI chr 3:4,146,462...4,178,880
Ensembl chr 3:4,147,308...4,177,888

arginine vasopressin

NCBI chr 2:33,761,066...33,764,608
Ensembl chr 2:33,761,140...33,763,172

BCL2 associated agonist of cell death

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

BAG cochaperone 1

NCBI chr12:47,006,177...47,016,177

BAK1

BCL2 antagonist/killer 1

DDT metabolite p,p'-DDE

PMID:18817839

RGD:2313963

NCBI chr17:38,492,776...38,502,534
Ensembl chr17:38,492,858...38,501,281

BRCA1 associated RING domain 1

propofol
citalopram, escitalopram

PMID:20498794 PMID:28467792

RGD:152025544 RGD:152025545

NCBI chr10:100,539,827...100,627,718
Ensembl chr10:100,539,527...100,627,675

BCL2 apoptosis regulator

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

BCL2 like 1

NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470

bone gamma-carboxyglutamate protein

bilirubin, hemin
streptozotocin

PMID:20020468 PMID:20818503

RGD:151667419 RGD:2316141

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

BIRC2

baculoviral IAP repeat containing 2

NCBI chr 1:93,721,449...93,746,638

bone morphogenetic protein 4

NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225

CACNA1B

calcium voltage-gated channel subunit alpha1 B

NCBI chr12:75,441...335,980
Ensembl chr12:78,011...335,820

CACNA1C

calcium voltage-gated channel subunit alpha1 C

Nifedipine

NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991

CALU

calumenin

anticoagulant bromadiolone

PMID:17994578

RGD:2316211

NCBI chr21:97,338,875...97,370,947
Ensembl chr21:97,338,913...97,373,156

caspase 1

paraquat

NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849

caspase 3

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

caspase 9

indole-3-carbinol

NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930

CASR

calcium sensing receptor

calcimimetic R-568

NCBI chr22:58,579,640...58,612,142
Ensembl chr22:58,578,396...58,604,756

C-C motif chemokine ligand 5

cyclophosphamide

NCBI chr16:29,351,214...29,361,317

CCN2

cellular communication network factor 2

glycyrrhizin

NCBI chr13:41,613,838...41,617,010
Ensembl chr13:41,613,798...41,617,651

cyclin D1

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

cyclin D2

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

cyclin E1

NCBI chr 6:24,879,923...24,888,985

CD44

CD44 molecule (IN blood group)

2-Fluorenylacetamide

PMID:17105903 PMID:31966914

RGD:2289368 RGD:25823185

NCBI chr 1:30,039,854...30,132,646
Ensembl chr 1:30,039,749...30,132,416

CD83

CD83 molecule

acts_upstream_of_or_within

(PMID:15322158)

PMID:15322158

NCBI chr17:58,022,817...58,052,041
Ensembl chr17:58,022,593...58,041,983

CDK1

cyclin dependent kinase 1

5-azacytidine

NCBI chr 9:70,475,736...70,492,947

cyclin dependent kinase inhibitor 1A

NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342

CDKN1B

cyclin dependent kinase inhibitor 1B

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

cofilin 1

doxorubicin

NCBI chr 1:8,408,560...8,410,564

collagen type I alpha 1 chain

streptozotocin

NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930

catechol-O-methyltransferase

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

CPT1A

carnitine palmitoyltransferase 1A

chiglitazar
18 beta, 20 beta-Glycyrrhizic acid

PMID:16751799 PMID:27939985 PMID:31918260

RGD:15036816 RGD:2311345 RGD:25823180

NCBI chr 1:5,704,275...5,784,077
Ensembl chr 1:5,730,853...5,784,337

CSF1

colony stimulating factor 1

streptozotocin

NCBI chr20:23,615,107...23,635,399

CSF1R

colony stimulating factor 1 receptor

streptozotocin

PMID:17000240 PMID:19219684 PMID:32141565

RGD:151665767 RGD:151665768 RGD:151665779

NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304

CST3

cystatin C

Isoproterenol (PubChem_Compound: 3779)

PMID:2757396

RGD:1299644

NCBI chr 2:52,834,497...52,838,785
Ensembl chr 2:52,832,181...52,838,865

catenin alpha 1

NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190

catenin beta 1

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

cathepsin B

kainic acid

NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854

cathepsin K

streptozotocin

cathepsin L

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

PMID:18465118

RGD:2315561

NCBI chr12:98,347,770...98,353,426
Ensembl chr12:98,347,800...98,353,467

CXCR4

C-X-C motif chemokine receptor 4

NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309

cytochrome P450 family 11 subfamily A member 1

tanning industry effluents
methyl p-hydroxybenzoate, propyl p-hydroxybenziate, butyl p-hydroxybenzoate
Methylparaben, propylparaben

PMID:18606229 PMID:22777679 PMID:28208728

RGD:151893504 RGD:151893505 RGD:4781442

NCBI chr26:9,122,008...9,151,844

CYP17A1

cytochrome P450 family 17 subfamily A member 1

di(n-butyl) phthalate

PMID:18923996

RGD:2317622

NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180

CYP19A1

cytochrome P450 family 19 subfamily A member 1

bisphenol-A
Methylparaben, propylparaben, butylparaben

PMID:20821433 PMID:28208728 PMID:30599193

RGD:151893501 RGD:151893505 RGD:4890046

NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277

CYP1A2

cytochrome P450 family 1 subfamily A member 2

NCBI chr26:8,727,996...8,733,254

cytochrome P450 family 1 subfamily B member 1

beta-naphthoflavone

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

CYP2B6

cytochrome P450 family 2 subfamily B member 6

Aroclor 1254

NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106

CYP2J2

cytochrome P450 family 2 subfamily J member 2

NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077

CYP7A1

cytochrome P450 family 7 subfamily A member 1

NCBI chr 8:54,475,801...54,489,329
Ensembl chr 8:54,477,105...54,485,649

DBH

dopamine beta-hydroxylase

capsaicin

NCBI chr12:4,474,041...4,498,942
Ensembl chr12:4,474,958...4,498,910

DHODH

dihydroorotate dehydrogenase (quinone)

polyporic acid

NCBI chr 5:55,161,788...55,177,383
Ensembl chr 5:55,161,916...55,180,896

DLX2

distal-less homeobox 2

streptozotocin

NCBI chr10:57,604,989...57,609,487
Ensembl chr10:57,606,084...57,608,079

DPYD

dihydropyrimidine dehydrogenase

NCBI chr20:35,376,738...36,215,388
Ensembl chr20:35,377,266...36,215,679

dopamine receptor D1

synthetic cannabinoid HU210

PMID:20673846

RGD:7248618

NCBI chr23:77,587,340...77,591,434

DUSP6

dual specificity phosphatase 6

dibutyl phthalate

NCBI chr11:84,741,957...84,747,038
Ensembl chr11:84,741,444...84,745,886

DUT

deoxyuridine triphosphatase

phenylhydrazine

NCBI chr26:34,941,775...34,954,184
Ensembl chr26:34,940,702...34,953,166

EDNRA

endothelin receptor type A

NCBI chr 7:93,980,983...94,043,863
Ensembl chr 7:93,985,797...94,042,296

EDNRB

endothelin receptor type B

NCBI chr 3:56,969,493...56,993,719
Ensembl chr 3:56,969,101...56,992,731

epidermal growth factor receptor

theaflavins

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

EIF4A3

eukaryotic translation initiation factor 4A3

kainic acid

NCBI chr16:72,097,692...72,113,112

enolase 2

NCBI chr11:6,945,243...6,954,959
Ensembl chr11:6,945,413...6,957,304

E1A binding protein p300

alpha1-adrenergic agonist phenylephrine

PMID:18292809

RGD:2312265

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

EPHX1

epoxide hydrolase 1

acts_upstream_of_or_within

(PMID:10446164)

PMID:10446164

NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535

ERCC8

ERCC excision repair 8, CSA ubiquitin ligase complex subunit

quinic acid carboxy alkyl esters

PMID:22900489

RGD:13208225

NCBI chr 4:57,048,262...57,128,338
Ensembl chr 4:57,045,018...57,128,307

estrogen receptor 2

involved_in

4-nitrophenol

RGD
UniProt

PMID:24070737

GO_REF:0000117 RGD:7364802

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

coagulation factor VII

warfarin

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

FADS1

fatty acid desaturase 1

NCBI chr 1:12,037,173...12,051,907
Ensembl chr 1:12,037,513...12,055,159

FGF10

fibroblast growth factor 10

di-n-butyl phthalate

NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432

FGF19

fibroblast growth factor 19

NCBI chr 1:4,852,289...4,860,139
Ensembl chr 1:4,854,363...4,859,102

FGF8

fibroblast growth factor 8

NCBI chr 9:94,797,157...94,803,725
Ensembl chr 9:94,798,088...94,803,629

FNTA

farnesyltransferase, CAAX box, subunit alpha

NCBI chr 8:41,057,798...41,088,210
Ensembl chr 8:41,057,603...41,087,705

FNTB

farnesyltransferase, CAAX box, subunit beta

NCBI chr24:42,197,998...42,275,863
Ensembl chr24:42,198,704...42,276,898

Fos proto-oncogene, AP-1 transcription factor subunit

streptozotocin

PMID:10934195 PMID:11113530 PMID:20818503

RGD:151667419 RGD:2293792 RGD:2293796

NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514

FOS like 1, AP-1 transcription factor subunit

NCBI chr 1:8,356,263...8,365,606
Ensembl chr 1:8,356,836...8,364,918

FOS like 2, AP-1 transcription factor subunit

NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373

forkhead box J1

NCBI chr16:45,536,973...45,544,331
Ensembl chr16:45,539,510...45,544,299

FOXL2

forkhead box L2

Methylparaben, propylparaben, butylparaben
methyl p-hydroxybenzoate, propyl p-hydroxybenziate, butyl p-hydroxybenzoate

PMID:22777679 PMID:28208728 PMID:30599193

RGD:151893501 RGD:151893504 RGD:151893505

NCBI chr15:51,595,806...51,598,124
Ensembl chr15:51,596,218...51,597,348

FSHR

follicle stimulating hormone receptor

Methylparaben, propylparaben

PMID:28208728

RGD:151893505

NCBI chr14:58,013,405...58,211,528
Ensembl chr14:58,013,742...58,212,755

follistatin

NCBI chr 4:49,773,646...49,780,343
Ensembl chr 4:49,773,980...49,780,333

frataxin

Alpha lipoic acid

NCBI chr12:80,133,899...80,173,950
Ensembl chr12:80,134,422...80,173,168

G6PD

glucose-6-phosphate dehydrogenase

stobadine

NCBI chr X:128,768,028...128,788,366
Ensembl chr X:128,770,268...128,786,961

GIP

gastric inhibitory polypeptide

methylprednisolone, alloxan

PMID:6753106

RGD:2312546

NCBI chr16:69,367,030...69,377,563
Ensembl chr16:69,367,207...69,377,155

GNAO1

G protein subunit alpha o1

NCBI chr 5:42,105,295...42,272,573
Ensembl chr 5:42,105,334...42,273,059

GNAT1

G protein subunit alpha transducin 1

acts_upstream_of_or_within

(PMID:31537864)

PMID:31537864

NCBI chr22:11,577,192...11,582,789
Ensembl chr22:11,577,997...11,581,223

GNAT2

G protein subunit alpha transducin 2

involved_in
acts_upstream_of_or_within

(PMID:31537864)

PMID:31537864

GO_REF:0000107

NCBI chr20:23,927,025...23,942,590
Ensembl chr20:23,933,737...23,942,490

GNRH1

gonadotropin releasing hormone 1

phorbol 12,13-dibutyrate

PMID:3282935

RGD:9685069

NCBI chr 8:23,543,717...23,550,728
Ensembl chr 8:23,542,806...23,547,771

glutathione peroxidase 1

NCBI chr22:10,754,976...10,756,617

GPX3

glutathione peroxidase 3

2,3,7,8-tetrachlorobenzo-p-dioxin

PMID:14673789

RGD:2312628

NCBI chr23:53,576,950...53,585,321

glutamate ionotropic receptor AMPA type subunit 1

cannabidiol

NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849

GRIN1

glutamate ionotropic receptor NMDA type subunit 1

ouabain

NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231

GRIN2A

glutamate ionotropic receptor NMDA type subunit 2A

ouabain

NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828

glutamate ionotropic receptor NMDA type subunit 2B

ouabain

NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202

G protein-coupled receptor kinase 2

NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259

GUCY1A1

guanylate cyclase 1 soluble subunit alpha 1

isoflavones

NCBI chr 7:102,206,438...102,310,535
Ensembl chr 7:102,238,477...102,303,673

HBE1

hemoglobin subunit epsilon 1

NCBI chr 1:61,450,297...61,453,203
Ensembl chr 1:61,451,654...61,453,074

HES1

hes family bHLH transcription factor 1

NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243

HMBS

hydroxymethylbilane synthase

heme arginate

NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095

3-hydroxy-3-methylglutaryl-CoA synthase 1

actein

NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409

3-hydroxy-3-methylglutaryl-CoA synthase 2

clofibrate

NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016

hippocalcin

Aroclor 1254

NCBI chr20:99,974,952...99,983,194
Ensembl chr20:99,975,742...99,980,728

HRH3

histamine receptor H3

NCBI chr 2:2,019,878...2,025,218
Ensembl chr 2:2,020,286...2,025,202

hydroxysteroid 17-beta dehydrogenase 3

wastewater treatment plant effluents

PMID:18001809

RGD:4831842

NCBI chr12:106,831,807...106,885,543
Ensembl chr12:106,832,034...106,886,385

HSD17B4

hydroxysteroid 17-beta dehydrogenase 4

diethylhexyl phthalate

PMID:16038268

RGD:10411895

NCBI chr23:22,674,059...22,761,270
Ensembl chr23:22,674,072...22,762,056

HSD17B7

hydroxysteroid 17-beta dehydrogenase 7

actein

NCBI chr20:1,271,259...1,289,232
Ensembl chr20:1,273,052...1,288,930

heat shock transcription factor 1

celastrol

NCBI chr 8:138,503,836...138,529,562
Ensembl chr 8:138,503,831...138,529,165

heat shock protein family D (Hsp60) member 1

NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363

ICAM1

intercellular adhesion molecule 1

carnosol

NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263

IDH1

isocitrate dehydrogenase (NADP(+)) 1

NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975

insulin like growth factor 1

polychlorinated biphenyls

PMID:19327374

RGD:2306695

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

IGF2

insulin like growth factor 2

2, 3, 7, 8-tetrachlorodibenzo-p-dioxin

PMID:17407073

RGD:2311525

NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388

IGFBP1

insulin like growth factor binding protein 1

Streptozotocin

NCBI chr21:12,932,727...12,939,078
Ensembl chr21:12,932,732...12,937,891

insulin like growth factor binding protein 2

Streptozotocin

NCBI chr10:102,469,611...102,503,229
Ensembl chr10:102,469,669...102,503,276

IGFBP3

insulin like growth factor binding protein 3

Streptozotocin

NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205

IGFBP4

insulin like growth factor binding protein 4

Streptozotocin

NCBI chr16:65,722,216...65,737,380
Ensembl chr16:65,723,361...65,737,072

IGFBP5

insulin like growth factor binding protein 5

Streptozotocin

NCBI chr10:102,510,939...102,531,710
Ensembl chr10:102,510,897...102,531,724

IGFBP7

insulin like growth factor binding protein 7

NCBI chr 7:11,617,096...11,694,530

IL1A

interleukin 1 alpha

vanadate

PMID:16087301 PMID:17696279

RGD:2311097 RGD:2311102

NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611

interleukin 1 beta

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

IL1RN

interleukin 1 receptor antagonist

NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326

interleukin 4

genistein

NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258

interleukin 6

5-fluorouracil

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

inhibin subunit beta B

di-2-ethylhexylphthalate

PMID:24641848

RGD:9743908

NCBI chr10:9,943,015...9,948,721

IRX1

iroquois homeobox 1

5-Aza-2'-deoxycytidine

PMID:31640472

RGD:329950496

NCBI chr 4:3,365,880...3,371,520
Ensembl chr 4:3,366,384...3,371,670

integrin subunit alpha 2

pilocarpine

NCBI chr 4:49,280,289...49,382,101
Ensembl chr 4:49,317,648...49,380,051

Janus kinase 2

NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710

JUN

Jun proto-oncogene, AP-1 transcription factor subunit

streptozotocin

PMID:11113530 PMID:20818503

RGD:151667419 RGD:2293792

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

JunB proto-oncogene, AP-1 transcription factor subunit

PMID:10934195 PMID:11113530

RGD:2293792 RGD:2293796

NCBI chr 6:11,479,108...11,480,942
Ensembl chr 6:11,479,407...11,480,450

JUND

JunD proto-oncogene, AP-1 transcription factor subunit

NCBI chr 6:16,754,553...16,756,458
Ensembl chr 6:16,755,247...16,756,290

KAT2A

lysine acetyltransferase 2A

furan

NCBI chr16:64,146,146...64,154,726
Ensembl chr16:64,146,207...64,154,252

KCNC2

potassium voltage-gated channel subfamily C member 2

kainic acid

NCBI chr11:70,603,034...70,770,625
Ensembl chr11:70,603,003...70,768,859

KCNQ2

potassium voltage-gated channel subfamily Q member 2

acts_upstream_of_or_within

(PMID:20885443)

PMID:20885443

NCBI chr 2:739,965...803,575
Ensembl chr 2:761,952...802,999

KCNQ3

potassium voltage-gated channel subfamily Q member 3

acts_upstream_of_or_within

(PMID:20885443)

PMID:20885443

NCBI chr 8:126,566,288...126,921,354
Ensembl chr 8:126,566,545...126,622,712

KDM1A

lysine demethylase 1A

dibutyl phthalate

NCBI chr20:109,592,761...109,657,885
Ensembl chr20:109,593,074...109,657,839

KITLG

KIT ligand

propylparaben, butylparaben
butyl p-hydroxybenzoate

PMID:22777679 PMID:28208728

RGD:151893504 RGD:151893505

NCBI chr11:83,856,149...83,943,095
Ensembl chr11:83,856,157...83,943,083

LDHA

lactate dehydrogenase A

NCBI chr 1:46,525,090...46,542,587

LEF1

lymphoid enhancer binding factor 1

NCBI chr 7:55,974,770...56,096,214
Ensembl chr 7:55,990,621...56,094,110

LIFR

LIF receptor subunit alpha

NCBI chr 4:37,307,753...37,385,489
Ensembl chr 4:37,314,347...37,362,137

LIPC

lipase C, hepatic type

cAMP
calcium channel antagonist nitrendipine

PMID:9721028 PMID:18675312

RGD:2307434 RGD:2307435

NCBI chr26:24,946,843...25,109,338
Ensembl chr26:24,946,673...25,087,921

LOC103218970

alpha-1-acid glycoprotein 1

3-methylcholanthrene

NCBI chr12:25,257,002...25,261,255
Ensembl chr12:25,256,969...25,260,446

perilipin-2

NCBI chr12:60,526,394...60,606,262
Ensembl chr12:60,590,222...60,610,727

LOC103219825

protein patched homolog 1

NCBI chr12:107,580,895...107,656,443
Ensembl chr12:107,590,663...107,652,985

LOC103223491

peroxisome proliferator-activated receptor alpha

NCBI chr19:28,614,892...28,709,272
Ensembl chr19:28,615,413...28,708,763

LOC103247994

DNA-binding protein inhibitor ID-1

bromocriptine, sulpiride

PMID:20600660

RGD:9686120

NCBI chr 2:36,008,660...36,009,880
Ensembl chr 2:36,008,636...36,010,017

LONP2

lon peptidase 2, peroxisomal

NCBI chr 5:34,050,284...34,160,363
Ensembl chr 5:34,050,446...34,160,165

LRP1B

LDL receptor related protein 1B

NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111

LRRC7

leucine rich repeat containing 7

NCBI chr20:63,016,441...63,567,809
Ensembl chr20:63,018,105...63,565,817

LUM

lumican

polychlorinated biphenyl (Aroclor 1254)

PMID:18602130

RGD:2303788

NCBI chr11:86,510,824...86,519,008
Ensembl chr11:86,509,722...86,519,010

LYN

LYN proto-oncogene, Src family tyrosine kinase

PubChem_Compound: 1066
PubChem_Compound: 1221

PMID:15287886 PMID:17265464

RGD:2303710 RGD:2303715

NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959

MBD1

methyl-CpG binding domain protein 1

bisphenol A

NCBI chr18:30,675,419...30,690,111
Ensembl chr18:30,675,653...30,685,946

MBD2

methyl-CpG binding domain protein 2

bisphenol A

NCBI chr18:26,714,610...26,785,028

MBD3

methyl-CpG binding domain protein 3

bisphenol A

NCBI chr 6:1,357,388...1,371,835
Ensembl chr 6:1,357,204...1,371,777

methyl-CpG binding protein 2

bisphenol A

NCBI chr X:128,445,028...128,519,892
Ensembl chr X:128,453,577...128,455,785

MET

MET proto-oncogene, receptor tyrosine kinase

adenosine

NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093

MGMT

O-6-methylguanine-DNA methyltransferase

coffee diterpene cafestol

PMID:12517412

RGD:2316915

NCBI chr 9:122,089,768...122,376,320

MKI67

marker of proliferation Ki-67

n-butylidenephthalide

NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866

MMP12

matrix metallopeptidase 12

NCBI chr 1:94,243,061...94,261,035
Ensembl chr 1:94,243,875...94,259,591

MMP14

matrix metallopeptidase 14

genistein

NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679

MMP9

matrix metallopeptidase 9

NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712

mutS homolog 2

NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819

MYD88

MYD88 innate immune signal transduction adaptor

involved_in

NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166

NAMPT

nicotinamide phosphoribosyltransferase

NCBI chr21:75,160,748...75,195,781
Ensembl chr21:75,158,596...75,196,025

Nanog homeobox

bisphenol A

NCBI chr11:7,813,309...7,820,009

NCF2

neutrophil cytosolic factor 2

puerarin

NCBI chr25:45,770,370...45,807,064
Ensembl chr25:45,770,641...45,806,515

NEDD8

NEDD8 ubiquitin like modifier

NCBI chr24:1,199,974...1,215,079

nuclear factor I A

NCBI chr20:71,573,729...72,171,268

NFKB1

nuclear factor kappa B subunit 1

zingerone

PMID:20211236 PMID:27939985

RGD:10045673 RGD:15036816

NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498

NFKB inhibitor alpha

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

nerve growth factor

4-methylcatechol

NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833

NK2 homeobox 2

conophylline

NCBI chr 2:50,499,802...50,511,309
Ensembl chr 2:50,500,691...50,502,438

NLRP3

NLR family pyrin domain containing 3

NCBI chr25:84,431,436...84,463,387
Ensembl chr25:84,434,527...84,463,249

NOS1

nitric oxide synthase 1

NCBI chr11:112,642,374...112,673,882

nitric oxide synthase 3

NCBI chr21:119,174,829...119,196,840

NPPB

natriuretic peptide B

NCBI chr20:119,930,931...119,933,391
Ensembl chr20:119,932,021...119,933,197

NQO1

NAD(P)H quinone dehydrogenase 1

Morin
Ferulic acid
Ramalin

PMID:21549141 PMID:29307993 PMID:30172374 PMID:31889292

RGD:21201308 RGD:25823194 RGD:25823195 RGD:5133234

NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599

NR0B2

nuclear receptor subfamily 0 group B member 2

NCBI chr20:105,850,328...105,853,076
Ensembl chr20:105,850,598...105,853,060

NR1H3

nuclear receptor subfamily 1 group H member 3

streptozotocin

NCBI chr 1:18,041,495...18,061,196
Ensembl chr 1:18,041,830...18,051,501

nuclear receptor subfamily 1 group H member 4

NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293

oxytocin/neurophysin I prepropeptide

neocuproine
genistein

PMID:12504828 PMID:19248249

RGD:2304085 RGD:2304189

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

OXTR

oxytocin receptor

genistein
phorbol myristate acetate

PMID:11264328 PMID:12504828

RGD:2304189 RGD:2304217

NCBI chr22:44,746,108...44,764,501
Ensembl chr22:44,742,419...44,763,243

P2RX2

purinergic receptor P2X 2

involved_in

CHEBI:50104|CHEBI:15422|CHEBI:45906

PMID:16388598

RGD:1642662

NCBI chr11:127,961,004...127,964,529
Ensembl chr11:127,961,079...127,964,113

purinergic receptor P2X 7

acts_upstream_of_or_within

(PMID:15240711)

PMID:15240711

NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059

PCSK1

proprotein convertase subtilisin/kexin type 1

forskolin

NCBI chr 4:90,246,413...90,289,148
Ensembl chr 4:90,248,598...90,289,089

PDGFB

platelet derived growth factor subunit B

quercetin

NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395

PDGFRB

platelet derived growth factor receptor beta

NCBI chr23:52,724,061...52,766,264
Ensembl chr23:52,724,005...52,766,234

PDX1

pancreatic and duodenal homeobox 1

AICAR, compound C

NCBI chr 3:7,038,088...7,046,593
Ensembl chr 3:7,041,466...7,045,976

phospholipase D2

NCBI chr16:4,283,248...4,298,034
Ensembl chr16:4,283,521...4,298,632

POLR2A

RNA polymerase II subunit A

NCBI chr16:6,860,487...6,889,054
Ensembl chr16:6,860,677...6,888,618

peroxisome proliferator activated receptor gamma

NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418

PPARG coactivator 1 alpha

pyrrolidine dithiocarbamate

PMID:23104933

RGD:7242021

NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582

protein phosphatase 1 regulatory subunit 15A

dopamine D2 receptor antagonist SCH23390

protein phosphatase 1 regulatory subunit 9B

butaprost and sulprostone

PMID:17408863

RGD:10043191

NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680

PRKCA

protein kinase C alpha

PMID:17845534 PMID:18278451

RGD:2292464 RGD:2292476

NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256

PRKCD

protein kinase C delta

NCBI chr22:14,561,401...14,592,877
Ensembl chr22:14,565,282...14,592,873

PRKCQ

protein kinase C theta

NCBI chr 9:6,532,438...6,675,708
Ensembl chr 9:6,532,319...6,621,487

prolactin

NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631

PSMB2

proteasome 20S subunit beta 2

NCBI chr20:97,232,632...97,270,608
Ensembl chr20:97,232,632...97,270,973

PTEN

phosphatase and tensin homolog

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

PTGER4

prostaglandin E receptor 4

RU-486

NCBI chr 4:39,440,697...39,453,983
Ensembl chr 4:39,440,276...39,454,004

PTGES

prostaglandin E synthase

NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435

PTGIS

prostaglandin I2 synthase

Bosentan
cPTIO

PMID:12964126 PMID:18612919

RGD:401901264 RGD:401960074

NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264

PTK2

protein tyrosine kinase 2

NCBI chr 8:134,897,511...135,246,300

RAD51

RAD51 recombinase

7,12-Dimethylbenz[a]anthracene

PMID:23969067

RGD:9831174

NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169

RAN

RAN, member RAS oncogene family

7,12-dimethylbenz[a]anthracene

PMID:16003757

RGD:9835417

NCBI chr11:126,257,849...126,263,481

RELA proto-oncogene, NF-kB subunit

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

reelin

5-aza-deoxycytidine

NCBI chr21:72,440,988...72,951,173
Ensembl chr21:72,440,160...72,950,747

ribosomal protein S6 kinase B1

NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453

RUNX2

RUNX family transcription factor 2

streptozotocin

NCBI chr17:26,679,386...26,807,812
Ensembl chr17:26,683,175...26,807,319

retinoid X receptor alpha

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

RXRG

retinoid X receptor gamma

NCBI chr25:63,444,128...63,490,594
Ensembl chr25:63,443,944...63,490,635

S100G

S100 calcium binding protein G

propyl p-hydroxybenziate, butyl p-hydroxybenzoate

PMID:22777679

RGD:151893504

NCBI chr X:15,082,230...15,087,327
Ensembl chr X:15,083,524...15,087,004

SCN5A

sodium voltage-gated channel alpha subunit 5

acts_upstream_of_or_within

(PMID:19745168)

PMID:19745168

NCBI chr15:767,854...869,787
Ensembl chr15:794,963...867,457

selectin P

NCBI chr25:59,420,910...59,465,140
Ensembl chr25:59,433,333...59,462,598

SERPINA1

serpin family A member 1

NCBI chr24:72,158,521...72,171,139
Ensembl chr24:72,156,784...72,163,500

SERPINF1

serpin family F member 1

taurocholate

NCBI chr16:1,408,453...1,424,197

SERPINH1

serpin family H member 1

PMID:12691502 PMID:12911538 PMID:32585450

RGD:41410779 RGD:41410781 RGD:41410783

NCBI chr 1:66,787,978...66,798,930
Ensembl chr 1:66,788,240...66,799,072

SETD2

SET domain containing 2, histone lysine methyltransferase

NCBI chr22:8,421,178...8,567,221
Ensembl chr22:8,420,960...8,567,201

secreted frizzled related protein 1

involved_in

GO_REF:0000107

NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984

SHC1

SHC adaptor protein 1

NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610

SLC10A1

solute carrier family 10 member 1

NCBI chr24:47,018,237...47,034,360
Ensembl chr24:47,017,414...47,033,940

SLC22A6

solute carrier family 22 member 6

methotrexate

NCBI chr 1:10,918,081...10,926,790
Ensembl chr 1:10,918,770...10,925,983

SLC22A8

solute carrier family 22 member 8

methotrexate

NCBI chr 1:10,885,895...10,909,739
Ensembl chr 1:10,886,690...10,910,546

SLC37A4

solute carrier family 37 member 4

NCBI chr 1:110,396,133...110,402,737
Ensembl chr 1:110,395,612...110,401,358

solute carrier family 6 member 1

NCBI chr22:47,033,436...47,076,785
Ensembl chr22:47,033,467...47,078,844

SLC6A3

solute carrier family 6 member 3

NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866

SLC7A11

solute carrier family 7 member 11

involved_in
acts_upstream_of_or_within

(PMID:21191088)

PMID:21191088

GO_REF:0000107

NCBI chr 7:85,149,810...85,225,061
Ensembl chr 7:85,154,068...85,225,144

SLC9A1

solute carrier family 9 member A1

NCBI chr20:105,613,289...105,670,868
Ensembl chr20:105,613,338...105,674,208

suppressor of cytokine signaling 3

NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423

SOX9

SRY-box transcription factor 9

NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898

SP7

Sp7 transcription factor

streptozotocin

NCBI chr11:49,436,976...49,456,741

SPHK1

sphingosine kinase 1

phorbol 12-myristate 13-acetate

PMID:15715670

RGD:2311352

NCBI chr16:45,290,147...45,295,175
Ensembl chr16:45,290,421...45,293,128

steroid 5 alpha-reductase 1

prolactin-inducing sulpiride

PMID:17940878

RGD:4891890

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

steroid 5 alpha-reductase 2

prolactin-inducing sulpiride

PMID:17940878

RGD:4891890

NCBI chr14:75,915,495...75,971,280
Ensembl chr14:75,917,260...75,970,365

SREBF1

sterol regulatory element binding transcription factor 1

PMID:19371623 PMID:27939985

RGD:15036816 RGD:8693606

NCBI chr16:16,847,603...16,874,239
Ensembl chr16:16,845,491...16,859,554

serine racemase

NCBI chr16:1,940,870...1,958,165
Ensembl chr16:1,940,893...1,956,783

steroidogenic acute regulatory protein

methoxychlor metabolite HPTE
Methylparaben, propylparaben, butylparaben
methyl p-hydroxybenzoate, propyl p-hydroxybenziate

PMID:16737795 PMID:22777679 PMID:28208728

RGD:151893504 RGD:151893505 RGD:1600076

NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583

signal transducer and activator of transcription 1

NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393

STAT3

signal transducer and activator of transcription 3

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

stanniocalcin 1

dibutyl phthalate

NCBI chr 8:21,975,286...21,988,182
Ensembl chr 8:21,975,283...21,988,198

steroid sulfatase

NCBI chr X:5,601,746...5,813,916
Ensembl chr X:5,709,410...5,812,224

TACR1

tachykinin receptor 1

apomorphine

NCBI chr14:32,080,319...32,236,556
Ensembl chr14:32,083,615...32,233,596

TAF2

TATA-box binding protein associated factor 2

paraquat

NCBI chr 8:114,291,325...114,395,189
Ensembl chr 8:114,290,866...114,395,537

TAF9B

TATA-box binding protein associated factor 9b

thiabendazole

NCBI chr X:67,097,313...67,106,076
Ensembl chr X:67,099,147...67,106,262

TAT

tyrosine aminotransferase

NCBI chr 5:54,695,342...54,749,291
Ensembl chr 5:54,693,458...54,705,082

TET2

tet methylcytosine dioxygenase 2

riddelliine, aristolochic acid

PMID:25154389

RGD:9586748

NCBI chr 7:53,193,824...53,326,813
Ensembl chr 7:53,193,941...53,326,942

transferrin

NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149

transforming growth factor beta 1

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

TGFBR1

transforming growth factor beta receptor 1

NCBI chr12:40,272,507...40,321,740
Ensembl chr12:40,276,916...40,297,372

TGFBR2

transforming growth factor beta receptor 2

NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711

tyrosine hydroxylase

curcumin

NCBI chr 1:1,969,194...1,977,263
Ensembl chr 1:1,966,460...1,977,218

TIMP3

TIMP metallopeptidase inhibitor 3

NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449

TNF

tumor necrosis factor

TNF receptor superfamily member 11a

streptozotocin

NCBI chr18:17,385,251...17,446,442

tumor protein p53

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

TP53I13

tumor protein p53 inducible protein 13

involved_in

(PMID:14767535)

PMID:14767535

NCBI chr16:23,307,144...23,313,272
Ensembl chr16:23,308,112...23,313,264

TPMT

thiopurine S-methyltransferase

D,L-homocysteine thiolactone

PMID:3994729

RGD:2315835

NCBI chr17:53,987,561...54,012,647
Ensembl chr17:53,987,559...54,014,650

triadin

Aroclor 1254

NCBI chr13:50,145,787...50,580,397

TRH

thyrotropin releasing hormone

NCBI chr22:51,075,814...51,079,852
Ensembl chr22:51,076,157...51,078,236

TRPA1

transient receptor potential cation channel subfamily A member 1

involved_in

GO_REF:0000107

NCBI chr 8:67,698,067...67,754,407
Ensembl chr 8:67,698,786...67,751,885

TWIST2

twist family bHLH transcription factor 2

streptozotocin

NCBI chr10:124,889,954...124,953,135
Ensembl chr10:124,890,134...124,890,613

TXN2

thioredoxin 2

Resveratrol
tetramethylpyrazine

PMID:18045550 PMID:18790005

RGD:2306159 RGD:5134340

NCBI chr19:19,168,693...19,185,898
Ensembl chr19:19,169,286...19,185,735

thymidylate synthetase

antiulcer agent ecabet sodium

PMID:9683817

RGD:5133446

NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856

UROD

uroporphyrinogen decarboxylase

phenylhydrazine

NCBI chr20:87,772,685...87,776,110
Ensembl chr20:87,772,261...87,775,978

VKORC1

vitamin K epoxide reductase complex subunit 1

NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640

Wnt family member 5A

nitrofen

NCBI chr22:16,809,454...16,836,815
Ensembl chr22:16,809,451...16,825,048

activation of prostate induction by androgen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

androgen receptor

acts_upstream_of_or_within

(PMID:17317769)

PMID:17317769

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

adenylate cyclase-activating dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenylate cyclase 5

acts_upstream_of_or_within

(PMID:12223546)

PMID:12223546

NCBI chr22:57,427,711...57,589,440

adenylate cyclase 5

involved_in

GO_REF:0000107

Ensembl chr22:57,441,880...57,588,891

dopamine receptor D1

acts_upstream_of_or_within
involved_in

(PMID:9016340)
(PMID:17194762)
(PMID:12223546)
(PMID:11923452), (PMID:12665504), (PMID:8738226)

PMID:8738226 PMID:9016340 PMID:11923452 PMID:12223546 PMID:12665504 More...

GO_REF:0000107 RGD:1581394 RGD:7248551

NCBI chr23:77,587,340...77,591,434

dopamine receptor D3

involved_in
acts_upstream_of_or_within

(PMID:18424554)
(PMID:16386234)

PMID:16386234 PMID:18424554

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

dopamine receptor D5

involved_in

PMID:12688394 PMID:15328036

GO_REF:0000107 RGD:1581394 RGD:1600979

NCBI chr27:40,267,681...40,270,061
Ensembl chr27:40,268,235...40,269,671

GNAL

G protein subunit alpha L

involved_in
acts_upstream_of_or_within

(PMID:17194762)

PMID:17194762

GO_REF:0000118

NCBI chr18:69,508,254...69,699,628
Ensembl chr18:69,510,512...69,635,000

LOC103243509

neuroendocrine secretory protein 55

involved_in
acts_upstream_of_or_within

PMID:18403039
(PMID:17194762)

PMID:17194762 PMID:18403039

RGD:8553387

NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192

LOC119618117

guanine nucleotide-binding protein G(s) subunit alpha

involved_in

GO_REF:0000118

Ensembl chr 2:5,233,874...5,249,192

NHERF1

NHERF family PDZ scaffold protein 1

involved_in
acts_upstream_of_or_within

(PMID:20200151)

PMID:20200151

GO_REF:0000107

NCBI chr16:46,889,454...46,910,776
Ensembl chr16:46,888,942...46,910,842

OPRD1

opioid receptor delta 1

NOT|acts_upstream_of_or_within

(PMID:8738226)

PMID:8738226

NCBI chr20:103,950,505...104,002,459

OPRM1

opioid receptor mu 1

acts_upstream_of_or_within

(PMID:8738226)

PMID:8738226

NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088

PTGER1

prostaglandin E receptor 1

involved_in

GO_REF:0000107

NCBI chr 6:13,131,328...13,134,457
Ensembl chr 6:13,131,424...13,133,190

adenylate cyclase-activating serotonin receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HTR7

5-hydroxytryptamine receptor 7

NCBI chr 9:84,081,713...84,191,112
Ensembl chr 9:84,083,396...84,190,876

adenylate cyclase-inhibiting dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenylate cyclase 5

acts_upstream_of_or_within

(PMID:12223546)

PMID:12223546

NCBI chr22:57,427,711...57,589,440

adenylate cyclase 5

involved_in

GO_REF:0000107

Ensembl chr22:57,441,880...57,588,891

dopamine receptor D2

involved_in
acts_upstream_of_or_within

InterPro
MGI
TreeGrafter
Ensembl

(PMID:12665504)
(PMID:12223546)

PMID:12223546 PMID:12665504

GO_REF:0000002 GO_REF:0000107 GO_REF:0000118

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

involved_in

InterPro
TreeGrafter

GO_REF:0000002 GO_REF:0000118

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

dopamine receptor D4

involved_in
acts_upstream_of_or_within

Ensembl
MGI
TreeGrafter
InterPro

(PMID:14684868)

PMID:14684868

GO_REF:0000002 GO_REF:0000107 GO_REF:0000118

NCBI chr 1:454,018...459,582

FLNA

filamin A

involved_in

GO_REF:0000107

NCBI chr X:128,657,580...128,683,812
Ensembl chr X:128,657,393...128,680,531

androgen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

androgen receptor

NOT|involved_in
acts_upstream_of_or_within

PMID:2341409 PMID:15199138 PMID:15660130 PMID:19244107

(PMID:19244107)
(PMID:15199138), (PMID:15660130)

UniProt
MGI
InterPro
RGD

GO_REF:0000002 RGD:1298681

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

ARID1A

AT-rich interaction domain 1A

involved_in

GO_REF:0000107

NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672

DAXX

death domain associated protein

involved_in

GO_REF:0000107

NCBI chr17:38,754,227...38,758,714
Ensembl chr17:38,754,280...38,759,071

DDX17

DEAD-box helicase 17

involved_in

GO_REF:0000107

NCBI chr19:21,145,576...21,167,091
Ensembl chr19:21,145,417...21,167,543

DDX5

DEAD-box helicase 5

involved_in

GO_REF:0000107

NCBI chr16:56,766,669...56,773,767
Ensembl chr16:56,767,186...56,773,464

DNAJA1

DnaJ heat shock protein family (Hsp40) member A1

acts_upstream_of_or_within

(PMID:15660130)

PMID:15660130

NCBI chr12:47,220,976...47,235,684

DNAJA1

DnaJ heat shock protein family (Hsp40) member A1

involved_in

GO_REF:0000107

Ensembl chr12:47,224,138...47,235,167

estrogen receptor 2

acts_upstream_of

(PMID:12370428)

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

FKBP4

FKBP prolyl isomerase 4

involved_in
acts_upstream_of_or_within

(PMID:17142810)

PMID:17142810

GO_REF:0000107

NCBI chr11:2,860,932...2,869,885
Ensembl chr11:2,860,935...2,870,383

insulin like growth factor 1

acts_upstream_of

(PMID:18827067)

PMID:18827067

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

KDM3A

lysine demethylase 3A

involved_in

GO_REF:0000107

NCBI chr14:20,668,215...20,721,854
Ensembl chr14:20,668,821...20,720,759

KDM4C

lysine demethylase 4C

involved_in

GO_REF:0000107

NCBI chr12:72,346,194...72,763,040
Ensembl chr12:72,347,071...72,761,666

LOC103234108

mammaglobin-B-like

involved_in

GO_REF:0000118

NCBI chr 1:11,614,795...11,620,608

LOC103234127

mammaglobin-B

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:11,647,470...11,653,227
Ensembl chr 1:11,647,648...11,652,561

mitogen-activated protein kinase 1

involved_in

GO_REF:0000107

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

NKX3-1

NK3 homeobox 1

involved_in

(PMID:19886863)

PMID:19886863

NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319

protein inhibitor of activated STAT 2

NCBI chr18:33,967,894...34,075,824
Ensembl chr18:33,967,999...34,067,910

RHOA

ras homolog family member A

involved_in
acts_upstream_of_or_within

(PMID:16254014)

PMID:16254014

GO_REF:0000107

NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704

RHOXF1

Rhox homeobox family member 1

involved_in

GO_REF:0000107

RWDD1

RWD domain containing 1

involved_in

(MGI:5882884|PMID:18761815)

PMID:18761815

MGI:5882884

NCBI chr13:57,215,415...57,238,455
Ensembl chr13:57,215,152...57,238,570

TMF1

TATA element modulatory factor 1

involved_in

GO_REF:0000107

NCBI chr22:30,048,269...30,078,600
Ensembl chr22:30,045,685...30,078,414

ubiquitin protein ligase E3A

acts_upstream_of_or_within

(PMID:16254014)

PMID:16254014

NCBI chr26:56,638,936...56,738,555
Ensembl chr26:56,666,162...56,736,737

ZDHHC7

zinc finger DHHC-type palmitoyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 5:70,379,228...70,419,885
Ensembl chr 5:70,379,179...70,401,139

ZMIZ1

zinc finger MIZ-type containing 1

involved_in

GO_REF:0000107

NCBI chr 9:52,150,810...52,414,793
Ensembl chr 9:52,148,075...52,259,728

behavioral response to cocaine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABAT

4-aminobutyrate aminotransferase

involved_in

(MGI:3691518|PMID:10850552)

PMID:10850552

MGI:3691518

NCBI chr 5:8,274,310...8,380,973
Ensembl chr 5:8,315,952...8,379,549

ADRA1B

adrenoceptor alpha 1B

acts_upstream_of_or_within

(PMID:11923452)

PMID:11923452

NCBI chr23:62,281,500...62,338,290

brain derived neurotrophic factor

NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336

CDK5

cyclin dependent kinase 5

acts_upstream_of_or_within

(PMID:18032670)

PMID:18032670

NCBI chr21:119,235,687...119,240,163

CREB binding protein

NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943

dopamine receptor D1

acts_upstream_of_or_within
involved_in

(PMID:16014726)

PMID:16014726 PMID:16377433

GO_REF:0000107 RGD:1581397

NCBI chr23:77,587,340...77,591,434

dopamine receptor D2

involved_in
acts_upstream_of_or_within

(PMID:17426149)

PMID:17426149

GO_REF:0000107

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

involved_in

PMID:8815892 PMID:10432116 PMID:16026479

(PMID:8815892)
(MGI:4418640|PMID:10432116)

RGD
BHF-UCL

MGI:4418640 RGD:7175068

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

dopamine receptor D4

involved_in
acts_upstream_of_or_within

(PMID:12783155), (PMID:9323127)

PMID:9323127 PMID:12783155

GO_REF:0000107

NCBI chr 1:454,018...459,582

EHMT2

euchromatic histone lysine methyltransferase 2

involved_in
acts_upstream_of_or_within

(PMID:24584053)

PMID:24584053

GO_REF:0000107

NCBI chr17:40,123,935...40,141,942
Ensembl chr17:40,124,640...40,141,616

FADD

Fas associated via death domain

NCBI chr 1:4,358,314...4,361,863

FosB proto-oncogene, AP-1 transcription factor subunit

PMID:20633205 PMID:25522720

RGD:401851063 RGD:401900126

NCBI chr 6:38,916,039...38,924,129

HOMER1

homer scaffold protein 1

acts_upstream_of_or_within

(PMID:15294147)

PMID:15294147

NCBI chr 4:73,591,105...73,729,680
Ensembl chr 4:73,589,495...73,728,353

HOMER2

homer scaffold protein 2

acts_upstream_of_or_within

(PMID:15294147)

PMID:15294147

NCBI chr29:2,667,718...2,810,238
Ensembl chr29:2,706,134...2,803,372

HTR2A

5-hydroxytryptamine receptor 2A

NCBI chr 3:24,820,029...24,884,472
Ensembl chr 3:24,820,035...24,883,432

LOC103243260

corticotropin-releasing factor receptor 1

NCBI chr16:60,070,156...60,120,857
Ensembl chr16:60,070,066...60,120,712

NOS1

nitric oxide synthase 1

NCBI chr11:112,642,374...112,673,882

OPRK1

opioid receptor kappa 1

NCBI chr 8:49,337,308...49,364,724
Ensembl chr 8:49,341,427...49,362,947

PARP1

poly(ADP-ribose) polymerase 1

acts_upstream_of_or_within

(PMID:24449909)

PMID:24449909

NCBI chr25:3,350,798...3,405,040

PPP1R1B

protein phosphatase 1 regulatory inhibitor subunit 1B

acts_upstream_of_or_within

(PMID:18496528)

PMID:18496528

NCBI chr16:66,530,640...66,541,025
Ensembl chr16:66,530,488...66,541,242

SDK1

sidekick cell adhesion molecule 1

acts_upstream_of_or_within

(PMID:24449909)

PMID:24449909

NCBI chr28:17,354,106...18,316,238
Ensembl chr28:17,351,241...17,998,205

SLC6A4

solute carrier family 6 member 4

NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616

synuclein alpha

NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479

cellular response to 2,3,7,8-tetrachlorodibenzodioxine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aryl hydrocarbon receptor

involved_in

Ensembl
UniProt

GO_REF:0000107 GO_REF:0000117

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

PDE2A

phosphodiesterase 2A

involved_in

GO_REF:0000107

NCBI chr 1:63,812,877...63,912,602
Ensembl chr 1:63,812,840...63,880,492

SLC46A3

solute carrier family 46 member 3

involved_in

GO_REF:0000107

NCBI chr 3:7,802,170...7,819,608
Ensembl chr 3:7,801,728...7,819,584

cellular response to 3,3',5-triiodo-L-thyronine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DYNC1H1

dynein cytoplasmic 1 heavy chain 1

NCBI chr24:79,915,719...80,008,666
Ensembl chr24:79,915,889...80,000,099

myosin-6

NCBI chr29:23,753,251...23,780,822
Ensembl chr29:23,753,309...23,778,107

myosin-7

NCBI chr29:23,783,610...23,804,981
Ensembl chr29:23,783,557...23,799,771

PNPLA3

patatin like phospholipase domain containing 3

NCBI chr19:26,435,302...26,458,368
Ensembl chr19:26,435,599...26,462,210

SIX homeobox 1

NCBI chr24:37,840,399...37,855,801
Ensembl chr24:37,840,309...37,845,192

cellular response to 3-methylcholanthrene

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aryl hydrocarbon receptor

involved_in

(MGI:49014|PMID:1314586)

PMID:1314586

MGI:49014

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

cellular response to aldosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AIFM1

apoptosis inducing factor mitochondria associated 1

NCBI chr X:105,383,408...105,419,146
Ensembl chr X:105,382,693...105,419,095

HCN2

hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

NCBI chr 6:326,437...358,119
Ensembl chr 6:324,517...358,119

HCN4

hyperpolarization activated cyclic nucleotide gated potassium channel 4

NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292

insulin like growth factor 1 receptor

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

NR3C2

nuclear receptor subfamily 3 group C member 2

PMID:10847590 PMID:16087789

RGD:152975666 RGD:401976479

NCBI chr 7:94,574,010...94,935,348

SCNN1A

sodium channel epithelial 1 subunit alpha

involved_in
acts_upstream_of_or_within

(PMID:20427473)

GO_REF:0000107

NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337

SCNN1B

sodium channel epithelial 1 subunit beta

involved_in
acts_upstream_of_or_within

(PMID:20427473)

GO_REF:0000107

NCBI chr 5:21,021,181...21,107,746
Ensembl chr 5:21,022,133...21,107,824

SCNN1G

sodium channel epithelial 1 subunit gamma

involved_in
acts_upstream_of_or_within

(PMID:20427473)

GO_REF:0000107

NCBI chr 5:20,860,062...20,924,628
Ensembl chr 5:20,891,416...20,924,819

serpin family E member 1

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

SGK1

serum/glucocorticoid regulated kinase 1

acts_upstream_of_or_within

(PMID:20427473)

NCBI chr13:39,152,289...39,306,190
Ensembl chr13:39,300,567...39,306,183

cellular response to ATP

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCC9

ATP binding cassette subfamily C member 9

acts_upstream_of_or_within

(PMID:20935152)
(PMID:24037327)

PMID:20935152 PMID:24037327

NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263

C-C motif chemokine ligand 2

NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416

CIB2

calcium and integrin binding family member 2

involved_in

(PMID:23023331), (PMID:26173970)

PMID:23023331 PMID:26173970

NCBI chr26:5,222,657...5,248,133
Ensembl chr26:5,222,902...5,248,191

HSP90B1

heat shock protein 90 beta family member 1

acts_upstream_of_or_within
involved_in

(PMID:19000834)

PMID:19000834

GO_REF:0000107

NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722

purinergic receptor P2X 3

involved_in

(PMID:27626375)
PMID:7566119

PMID:7566119 PMID:27626375

RGD:729168

NCBI chr 1:15,872,124...15,906,452

purinergic receptor P2X 3

involved_in

GO_REF:0000107

Ensembl chr 1:15,893,197...15,906,116

P2RX4

purinergic receptor P2X 4

enables
involved_in

PMID:8551329 PMID:10515189 PMID:16282518

PMID:8551329
(PMID:10515189)

RGD
UniProt

RGD:1642691 RGD:61682

NCBI chr11:116,585,276...116,609,401
Ensembl chr11:116,585,586...116,609,511

P2RY11

purinergic receptor P2Y11

involved_in

(PMID:18048695)

PMID:18048695

NCBI chr 6:9,180,132...9,183,643

P2RY11

purinergic receptor P2Y11

involved_in

GO_REF:0000107

Ensembl chr 6:9,180,548...9,183,532

P2RY12

purinergic receptor P2Y12

involved_in

ARUK-UCL
ParkinsonsUK-UCL

PMID:20091784
(MGI:3693016|PMID:17115040)

PMID:17115040 PMID:20091784

MGI:3693016 RGD:6480646

NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637

prostaglandin-endoperoxide synthase 2

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

RYR1

ryanodine receptor 1

involved_in

PMID:11316255

NCBI chr 6:33,080,443...33,234,478
Ensembl chr 6:33,080,758...33,213,788

serpin family E member 1

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

SOD1

superoxide dismutase 1

NCBI chr 2:60,461,219...60,472,999

SSH1

slingshot protein phosphatase 1

acts_upstream_of_or_within

(PMID:19000834)

PMID:19000834

NCBI chr11:103,982,889...104,059,673

TAF1

TATA-box binding protein associated factor 1

involved_in

(PMID:24289924)

ParkinsonsUK-UCL

PMID:24289924

NCBI chr X:61,167,743...61,269,000
Ensembl chr X:61,167,589...61,268,839

TOP2B

DNA topoisomerase II beta

NCBI chr15:70,266,267...70,332,079
Ensembl chr15:70,266,601...70,332,824

TRPM4

transient receptor potential cation channel subfamily M member 4

involved_in

GO_REF:0000107

NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146

TRPV1

transient receptor potential cation channel subfamily V member 1

involved_in

PMID:17582331

NCBI chr16:3,071,158...3,091,068
Ensembl chr16:3,071,526...3,090,330

cellular response to bile acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCB4

ATP binding cassette subfamily B member 4

involved_in

(PMID:17523162)

PMID:17523162

NCBI chr21:61,459,344...61,529,017

GPBAR1

G protein-coupled bile acid receptor 1

involved_in

GO_REF:0000107

NCBI chr10:104,141,177...104,145,557
Ensembl chr10:104,144,421...104,145,413

HAMP

hepcidin antimicrobial peptide

NCBI chr 6:30,214,820...30,218,100
Ensembl chr 6:30,215,563...30,217,996

KCNMB1

potassium calcium-activated channel subfamily M regulatory beta subunit 1

NCBI chr23:72,580,617...72,591,070
Ensembl chr23:72,577,813...72,591,588

nuclear receptor subfamily 1 group H member 4

involved_in

GO_REF:0000107

NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293

cellular response to bisphenol A

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

checkpoint kinase 2

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

DNA methyltransferase 1

involved_in
acts_upstream_of_or_within

(PMID:21980460)

PMID:21980460

GO_REF:0000107

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

DNMT3A

DNA methyltransferase 3 alpha

acts_upstream_of_or_within

(PMID:21980460)

PMID:21980460

NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819

solute carrier family 1 member 1

acts_upstream_of_or_within

(PMID:21980460)

PMID:21980460

NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369

cellular response to caffeine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CASQ2

calsequestrin 2

involved_in

GO_REF:0000107

NCBI chr20:17,937,089...18,008,433
Ensembl chr20:17,937,524...18,008,786

checkpoint kinase 1

NCBI chr 1:116,768,141...116,809,557
Ensembl chr 1:116,767,944...116,801,371

LOC103234112

trimeric intracellular cation channel type A

acts_upstream_of_or_within

(PMID:17611541)

PMID:17611541

NCBI chr 6:15,169,143...15,200,372
Ensembl chr 6:15,170,033...15,200,481

PPARG coactivator 1 alpha

NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582

RYR1

ryanodine receptor 1

involved_in

GO_REF:0000107

NCBI chr 6:33,080,443...33,234,478
Ensembl chr 6:33,080,758...33,213,788

RYR2

ryanodine receptor 2

involved_in
acts_upstream_of_or_within

(PMID:12089338)

PMID:12089338

GO_REF:0000107

NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451

SELENON

selenoprotein N

acts_upstream_of_or_within

(PMID:23325319)

PMID:23325319

NCBI chr20:106,953,286...106,971,249

SLC8A1

solute carrier family 8 member A1

involved_in

(MGI:1927695|PMID:10967099)

PMID:10967099

MGI:1927695

NCBI chr14:66,813,523...67,210,261

TMEM38B

transmembrane protein 38B

involved_in
acts_upstream_of_or_within

(PMID:17611541)

PMID:17611541

GO_REF:0000107

NCBI chr12:33,759,311...33,840,357
Ensembl chr12:33,759,157...33,840,009

TRPA1

transient receptor potential cation channel subfamily A member 1

NCBI chr 8:67,698,067...67,754,407
Ensembl chr 8:67,698,786...67,751,885

cellular response to cAMP

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aralkylamine N-acetyltransferase

involved_in

GO_REF:0000107

NCBI chr16:45,206,233...45,215,761
Ensembl chr16:45,206,377...45,207,591

ADIPOQ

adiponectin, C1Q and collagen domain containing

NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391

aryl hydrocarbon receptor

involved_in

GO_REF:0000107

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

AKAP1

A-kinase anchoring protein 1

CPT-cAMP

NCBI chr16:36,275,287...36,313,612
Ensembl chr16:36,275,209...36,306,012

AKAP7

A-kinase anchoring protein 7

involved_in

(PMID:11299204)

PMID:11299204

NCBI chr13:42,270,160...42,418,728

AKAP9

A-kinase anchoring protein 9

involved_in

GO_REF:0000107

NCBI chr21:56,889,669...57,061,526
Ensembl chr21:56,890,183...57,061,232

APEX1

apurinic/apyrimidinic endodeoxyribonuclease 1

NCBI chr29:20,978,878...20,981,393

APP

amyloid beta precursor protein

NCBI chr 2:66,037,224...66,320,860
Ensembl chr 2:66,037,261...66,321,306

AQP1

aquaporin 1 (Colton blood group)

involved_in

GO_REF:0000107

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

AQP8

aquaporin 8

involved_in

GO_REF:0000107

NCBI chr 5:22,928,230...22,940,814
Ensembl chr 5:22,928,350...22,940,856

AQP9

aquaporin 9

involved_in

GO_REF:0000107

NCBI chr26:25,326,108...25,374,743
Ensembl chr26:25,326,087...25,373,336

argininosuccinate lyase

NCBI chr28:1,782,434...1,800,581
Ensembl chr28:1,782,553...1,802,517

argininosuccinate synthase 1

NCBI chr12:7,643,484...7,701,334

ATP5PO

ATP synthase peripheral stalk subunit OSCP

NCBI chr 2:58,273,181...58,285,615

BCL2 like 1

NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470

CFTR

CF transmembrane conductance regulator

involved_in

(MGI:5429843|PMID:21976599)

PMID:21976599

MGI:5429843

NCBI chr21:86,154,313...86,332,436

carbamoyl-phosphate synthase 1

NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206

CRHBP

corticotropin releasing hormone binding protein

involved_in

(MGI:5315350|PMID:15976007)

PMID:15976007

MGI:5315350

NCBI chr 4:71,203,335...71,223,179
Ensembl chr 4:71,205,932...71,223,172

cytochrome P450 family 11 subfamily A member 1

NCBI chr26:9,122,008...9,151,844

cytochrome P450 family 1 subfamily B member 1

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

DMTN

dematin actin binding protein

involved_in

GO_REF:0000107

NCBI chr 8:20,120,054...20,154,368
Ensembl chr 8:20,125,703...20,152,985

EEF2K

eukaryotic elongation factor 2 kinase

NCBI chr 5:19,871,669...19,957,471
Ensembl chr 5:19,871,310...19,957,395

early growth response 1

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

NCBI chr13:41,670,416...41,755,549

E1A binding protein p300

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

EZR

ezrin

involved_in

(PMID:17911601)

PMID:17911601

NCBI chr13:86,342,954...86,399,827
Ensembl chr13:86,344,051...86,370,622

FBP1

fructose-bisphosphatase 1

NCBI chr12:108,452,856...108,484,052
Ensembl chr12:108,453,156...108,483,775

FDX1

ferredoxin 1

involved_in
acts_upstream_of_or_within

(PMID:7495857)

PMID:7495857

GO_REF:0000107

NCBI chr 1:101,777,499...101,813,753
Ensembl chr 1:101,777,678...101,816,379

GATA1

GATA binding protein 1

NCBI chr X:45,912,638...45,920,415
Ensembl chr X:45,917,231...45,920,268

GPD1

glycerol-3-phosphate dehydrogenase 1

involved_in
acts_upstream_of_or_within

(PMID:3027100)

PMID:3027100

GO_REF:0000107

NCBI chr11:46,329,479...46,339,227
Ensembl chr11:46,331,569...46,337,439

HCN1

hyperpolarization activated cyclic nucleotide gated potassium channel 1

involved_in

(MGI:5520040|PMID:22006928)
(PMID:22748890)
(PMID:28086084)

PMID:22006928 PMID:22748890 PMID:28086084

MGI:5520040

NCBI chr 4:44,029,173...44,443,669

HCN2

hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

involved_in

(PMID:10228147), (PMID:22748890)

PMID:10228147 PMID:22748890

NCBI chr 6:326,437...358,119
Ensembl chr 6:324,517...358,119

HCN3

hyperpolarization activated cyclic nucleotide gated potassium channel 3

NOT|involved_in

(PMID:22748890)

PMID:22748890

NCBI chr20:8,546,609...8,558,911
Ensembl chr20:8,545,720...8,558,056

HCN4

hyperpolarization activated cyclic nucleotide gated potassium channel 4

involved_in

GO_REF:0000107

NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292

HSPA5

heat shock protein family A (Hsp70) member 5

NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431

IGFBP5

insulin like growth factor binding protein 5

involved_in

(PMID:7559606)

PMID:7559606

NCBI chr10:102,510,939...102,531,710
Ensembl chr10:102,510,897...102,531,724

interleukin 18

NCBI chr 1:103,485,868...103,511,632
Ensembl chr 1:103,482,083...103,510,150

inhibin subunit beta B

NCBI chr10:9,943,015...9,948,721

INPP5K

inositol polyphosphate-5-phosphatase K

involved_in

GO_REF:0000107

NCBI chr16:1,171,059...1,192,241
Ensembl chr16:1,170,899...1,191,965

ITPR1

inositol 1,4,5-trisphosphate receptor type 1

NCBI chr22:40,574,569...40,925,857
Ensembl chr22:40,574,374...40,926,842

ITPR2

inositol 1,4,5-trisphosphate receptor type 2

involved_in

GO_REF:0000107

NCBI chr11:26,089,480...26,574,621
Ensembl chr11:26,089,484...26,574,950

ITPR3

inositol 1,4,5-trisphosphate receptor type 3

NCBI chr17:38,381,862...38,456,505
Ensembl chr17:38,381,743...38,456,499

KCNE1

potassium voltage-gated channel subfamily E regulatory subunit 1

involved_in

(PMID:18093912)
(PMID:11299204), (PMID:16002409)

PMID:11299204 PMID:16002409 PMID:18093912

NCBI chr 2:78,500,755...78,557,275
Ensembl chr 2:78,503,317...78,503,757

KCNQ1

potassium voltage-gated channel subfamily Q member 1

involved_in

GO_REF:0000107

NCBI chr 1:2,261,448...2,661,840
Ensembl chr 1:2,261,845...2,661,863

KDM1A

lysine demethylase 1A

NCBI chr20:109,592,761...109,657,885
Ensembl chr20:109,593,074...109,657,839

LOC103215555

ras-related protein Rap-1b

involved_in

GO_REF:0000118

NCBI chr 8:27,133,883...27,135,032

LOC103219406

ras-related protein Rap-1b-like

involved_in

GO_REF:0000118

NCBI chr12:60,987,851...60,990,521

LOC103221883

uncharacterized LOC103221883

involved_in

(PMID:12121997)
(PMID:19218243)

PMID:12121997 PMID:19218243

NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027

mitogen-activated protein kinase 1

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

nitric oxide synthase 3

NCBI chr21:119,174,829...119,196,840

NADPH oxidase 4

NCBI chr 1:80,470,418...80,642,513
Ensembl chr 1:80,470,826...80,642,722

PCK1

phosphoenolpyruvate carboxykinase 1

PMID:9530152 PMID:18335579

RGD:10445832 RGD:151665787

NCBI chr 2:6,550,806...6,556,499
Ensembl chr 2:6,549,652...6,556,478

PDE2A

phosphodiesterase 2A

involved_in

GO_REF:0000107

NCBI chr 1:63,812,877...63,912,602
Ensembl chr 1:63,812,840...63,880,492

proenkephalin

NCBI chr 8:52,458,113...52,463,933
Ensembl chr 8:52,457,904...52,463,859

PIK3CG

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

involved_in
acts_upstream_of_or_within

(PMID:23008439)

PMID:23008439

GO_REF:0000107

NCBI chr21:75,781,812...75,823,404
Ensembl chr21:75,784,648...75,825,496

PKD2

polycystin 2, transient receptor potential cation channel

involved_in

GO_REF:0000107

NCBI chr 7:36,369,226...36,445,713
Ensembl chr 7:36,369,524...36,443,612

PTAFR

platelet activating factor receptor

NCBI chr20:104,627,591...104,658,840
Ensembl chr20:104,657,179...104,658,207

RAP1A

RAP1A, member of RAS oncogene family

involved_in

RGD
TreeGrafter
Ensembl

PMID:20339002

GO_REF:0000107 GO_REF:0000118 RGD:10003134

NCBI chr20:21,895,829...21,989,008
Ensembl chr20:21,899,669...21,917,350

RAP1B

RAP1B, member of RAS oncogene family

involved_in

GO_REF:0000118

NCBI chr11:64,240,501...64,290,515
Ensembl chr11:64,240,651...64,286,727

RAPGEF1

Rap guanine nucleotide exchange factor 1

involved_in

(PMID:21840392)

PMID:21840392

NCBI chr12:6,407,030...6,566,200
Ensembl chr12:6,437,454...6,567,436

RAPGEF2

Rap guanine nucleotide exchange factor 2

involved_in

(PMID:10801446), (PMID:16272156), (PMID:21840392), (PMID:23800469)
(MGI:5514088|PMID:23800469)
(MGI:5499726|PMID:16272156)

PMID:10801446 PMID:16272156 PMID:21840392 PMID:23800469

MGI:5499726 MGI:5514088

NCBI chr 7:105,672,583...105,883,544
Ensembl chr 7:105,624,608...105,884,366

RAPGEF3

Rap guanine nucleotide exchange factor 3

involved_in

(PMID:21840392)

PMID:21840392

NCBI chr11:43,954,517...43,979,068
Ensembl chr11:43,957,425...43,978,047

RPL13A

ribosomal protein L13a

NCBI chr 6:42,666,186...42,671,018

RPLP0

ribosomal protein lateral stalk subunit P0

NCBI chr11:115,547,430...115,552,242
Ensembl chr11:115,547,427...115,550,209

RPLP1

ribosomal protein lateral stalk subunit P1

NCBI chr26:14,002,074...14,004,481
Ensembl chr26:14,002,075...14,004,474

RPLP2

ribosomal protein lateral stalk subunit P2

NCBI chr 1:617,401...620,656
Ensembl chr 1:612,490...620,805

serpin family E member 1

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

SLC26A3

solute carrier family 26 member 3

involved_in

(MGI:5429843|PMID:21976599)

PMID:21976599

MGI:5429843

NCBI chr21:76,682,255...76,739,460
Ensembl chr21:76,681,951...76,721,139

SLC26A6

solute carrier family 26 member 6

involved_in

(MGI:5466469|PMID:22895259)

PMID:22895259

MGI:5466469

NCBI chr22:10,035,676...10,046,274
Ensembl chr22:10,035,478...10,045,304

SLC5A5

solute carrier family 5 member 5

involved_in

(PMID:12021185)

PMID:12021185

NCBI chr 6:16,346,361...16,367,833

SLC8A1

solute carrier family 8 member A1

NCBI chr14:66,813,523...67,210,261

SLC8A3

solute carrier family 8 member A3

NCBI chr24:47,287,487...47,428,608
Ensembl chr24:47,288,256...47,427,776

steroid 5 alpha-reductase 1

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

steroidogenic acute regulatory protein

NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583

stanniocalcin 1

NCBI chr 8:21,975,286...21,988,182
Ensembl chr 8:21,975,283...21,988,198

transferrin

involved_in

PMID:15831523

NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149

WNT10B

Wnt family member 10B

acts_upstream_of_or_within

(PMID:12055200)

NCBI chr11:45,205,728...45,229,050
Ensembl chr11:45,205,566...45,210,893

WT1

WT1 transcription factor

involved_in

GO_REF:0000107

NCBI chr 1:32,750,300...32,801,832

ZFP36L1

ZFP36 ring finger protein like 1

involved_in

(PMID:19179481)
(MGI:5784985|PMID:19179481)

PMID:19179481

MGI:5784985

NCBI chr24:46,000,222...46,005,455
Ensembl chr24:45,999,623...46,006,218

cellular response to camptothecin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BLM

BLM RecQ like helicase

involved_in

(PMID:23509288)

PMID:23509288

NCBI chr29:9,046,485...9,152,320
Ensembl chr29:9,045,373...9,152,254

FANCB

FA complementation group B

acts_upstream_of_or_within

(PMID:25520194)

PMID:25520194

NCBI chr X:13,321,304...13,352,368
Ensembl chr X:13,321,527...13,342,478

RAD51

RAD51 recombinase

involved_in

GO_REF:0000107

NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169

RECQL5

RecQ like helicase 5

involved_in
acts_upstream_of_or_within

(PMID:25520194)

PMID:25520194

GO_REF:0000107

NCBI chr16:46,013,100...46,052,713
Ensembl chr16:46,013,092...46,056,167

SPIDR

scaffold protein involved in DNA repair

involved_in

(PMID:23509288)

PMID:23509288

NCBI chr 8:43,380,207...43,872,077
Ensembl chr 8:43,380,244...43,872,937

cellular response to catecholamine stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY6

adenylate cyclase 6

involved_in

GO_REF:0000107

NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501

dopamine receptor D1

involved_in

GO_REF:0000107

NCBI chr23:77,587,340...77,591,434

dopamine receptor D5

involved_in

GO_REF:0000107

NCBI chr27:40,267,681...40,270,061
Ensembl chr27:40,268,235...40,269,671

G protein-coupled receptor kinase 2

NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259

LOC103243509

neuroendocrine secretory protein 55

involved_in

PMID:18403039

NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192

NR4A3

nuclear receptor subfamily 4 group A member 3

involved_in

(MGI:5645208|PMID:18325999)

PMID:18325999

MGI:5645208

NCBI chr12:39,568,085...39,611,704
Ensembl chr12:39,567,852...39,606,837

cellular response to cGMP

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HCN2

hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

involved_in

(PMID:22748890)

PMID:22748890

NCBI chr 6:326,437...358,119
Ensembl chr 6:324,517...358,119

HCN4

hyperpolarization activated cyclic nucleotide gated potassium channel 4

involved_in

GO_REF:0000107

NCBI chr26:10,107,342...10,158,885
Ensembl chr26:10,110,579...10,156,292

NPR2

natriuretic peptide receptor 2

involved_in

(PMID:26522847)

PMID:26522847

NCBI chr12:44,795,822...44,844,464
Ensembl chr12:44,793,253...44,813,671

PDE2A

phosphodiesterase 2A

involved_in

GO_REF:0000107

NCBI chr 1:63,812,877...63,912,602
Ensembl chr 1:63,812,840...63,880,492

PDE3A

phosphodiesterase 3A

involved_in

(PMID:17704206)

PMID:17704206

NCBI chr11:20,235,814...20,545,740
Ensembl chr11:20,236,430...20,540,900

RAPGEF2

Rap guanine nucleotide exchange factor 2

involved_in

(PMID:10801446)

PMID:10801446

NCBI chr 7:105,672,583...105,883,544
Ensembl chr 7:105,624,608...105,884,366

serpin family E member 1

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

SLC6A4

solute carrier family 6 member 4

NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616

cellular response to chloroquine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LOC103227720

twinfilin-2

involved_in

GO_REF:0000107

NCBI chr22:13,581,102...13,598,830
Ensembl chr22:13,589,034...13,598,752
Ensembl chr22:13,589,034...13,598,752

cellular response to cholesterol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

acetoacetyl-CoA synthetase

25-hydroxycholesterol

PMID:3663886

RGD:2326225

NCBI chr11:120,422,138...120,502,200
Ensembl chr11:120,422,232...120,502,271

ABCA1

ATP binding cassette subfamily A member 1

PMID:15907796 PMID:17526932

RGD:1598535 RGD:2308820

NCBI chr12:34,587,123...34,734,936
Ensembl chr12:34,587,118...34,731,642

apolipoprotein E

NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438

CYP7A1

cytochrome P450 family 7 subfamily A member 1

involved_in

PMID:1694852

NCBI chr 8:54,475,801...54,489,329
Ensembl chr 8:54,477,105...54,485,649

dystroglycan 1

NCBI chr22:10,864,058...10,934,179
Ensembl chr22:10,865,724...10,934,200

DLL4

delta like canonical Notch ligand 4

NCBI chr26:42,056,473...42,066,283
Ensembl chr26:42,056,331...42,065,828

GPLD1

glycosylphosphatidylinositol specific phospholipase D1

involved_in

(PMID:17761367)

PMID:17761367

NCBI chr17:47,748,183...47,809,459
Ensembl chr17:47,765,699...47,804,378

GPR155

G protein-coupled receptor 155

involved_in

GO_REF:0000107

NCBI chr10:59,941,613...59,993,896
Ensembl chr10:59,945,483...59,989,998

GRAMD1A

GRAM domain containing 1A

involved_in

(MGI:6242147|PMID:30220461)

PMID:30220461

MGI:6242147

NCBI chr 6:29,928,068...29,958,839
Ensembl chr 6:29,937,053...29,961,093

GRAMD1B

GRAM domain containing 1B

involved_in

GO_REF:0000107

NCBI chr 1:114,746,337...115,023,174
Ensembl chr 1:114,822,815...115,023,878

GRAMD1C

GRAM domain containing 1C

involved_in

GO_REF:0000107

NCBI chr22:66,917,212...67,021,575
Ensembl chr22:66,918,899...67,021,409

3-hydroxy-3-methylglutaryl-CoA synthase 1

24S-hydroxycholesterol

PMID:18303831

RGD:2326114

NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409

INHBA

inhibin subunit beta A

involved_in

PMID:19464342

NCBI chr21:16,936,054...16,951,430
Ensembl chr21:16,936,175...16,946,880

inhibin subunit beta B

involved_in

PMID:19464342

NCBI chr10:9,943,015...9,948,721

LOC103219825

protein patched homolog 1

involved_in

(MGI:5306540|PMID:21931618)
(PMID:11278759)

PMID:11278759 PMID:21931618

MGI:5306540

NCBI chr12:107,580,895...107,656,443
Ensembl chr12:107,590,663...107,652,985

LOC103233018

liver carboxylesterase 1

involved_in

(PMID:18762277)

PMID:18762277

NCBI chr 5:41,710,500...41,745,483

LRP6

LDL receptor related protein 6

involved_in

(PMID:16890161)

PMID:16890161

NCBI chr11:12,016,542...12,170,496
Ensembl chr11:12,021,560...12,170,663

LRP8

LDL receptor related protein 8

NCBI chr20:79,596,138...79,681,924
Ensembl chr20:79,596,370...79,677,278

MLC1

modulator of VRAC current 1

involved_in

PMID:19931615

NCBI chr19:32,559,208...32,583,522
Ensembl chr19:32,557,536...32,583,060

NFE2L1

NFE2 like bZIP transcription factor 1

involved_in
acts_upstream_of_or_within

(MGI:6101031|PMID:29149604)
(PMID:29149604)

UniProt
MGI

PMID:29149604

MGI:6101031

NCBI chr16:68,449,601...68,463,030
Ensembl chr16:68,449,898...68,461,190

OSBPL7

oxysterol binding protein like 7

involved_in

(PMID:21669198)

PMID:21669198

NCBI chr16:68,208,121...68,222,684

OSBPL7

oxysterol binding protein like 7

involved_in

GO_REF:0000107

Ensembl chr16:68,215,177...68,222,651

SCP2

sterol carrier protein 2

PMID:7989577 PMID:8847489

RGD:9850161 RGD:9850255

NCBI chr20:79,868,825...79,993,906
Ensembl chr20:79,865,332...79,993,835

SMO

smoothened, frizzled class receptor

involved_in

GO_REF:0000107

NCBI chr21:97,788,955...97,814,549
Ensembl chr21:97,788,624...97,814,709

cellular response to cocaine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cyclin A2

NCBI chr 7:69,092,410...69,100,191
Ensembl chr 7:69,093,543...69,099,497

catechol-O-methyltransferase

acts_upstream_of_or_within

(PMID:17881525)

PMID:17881525

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

corticotropin releasing hormone

involved_in

PMID:14751291

NCBI chr 8:62,052,155...62,056,424
Ensembl chr 8:62,052,592...62,053,182

CRHBP

corticotropin releasing hormone binding protein

involved_in

PMID:14751291

NCBI chr 4:71,203,335...71,223,179
Ensembl chr 4:71,205,932...71,223,172

EHMT2

euchromatic histone lysine methyltransferase 2

involved_in
acts_upstream_of_or_within

(PMID:24584053)

PMID:24584053

GO_REF:0000107

NCBI chr17:40,123,935...40,141,942
Ensembl chr17:40,124,640...40,141,616

PPP1R1B

protein phosphatase 1 regulatory inhibitor subunit 1B

acts_upstream_of_or_within

(PMID:18496528)

PMID:18496528

NCBI chr16:66,530,640...66,541,025
Ensembl chr16:66,530,488...66,541,242

solute carrier family 1 member 1

involved_in

(PMID:27208619)

PMID:27208619

NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369

SLC1A2

solute carrier family 1 member 2

involved_in

GO_REF:0000107

NCBI chr 1:29,845,512...30,012,261
Ensembl chr 1:29,847,043...29,989,975

SLC1A3

solute carrier family 1 member 3

involved_in

GO_REF:0000107

NCBI chr 4:35,473,425...35,557,118
Ensembl chr 4:35,473,658...35,557,138

TGM2

transglutaminase 2

involved_in

(PMID:32273471)

PMID:32273471

NCBI chr 2:25,585,827...25,623,961
Ensembl chr 2:25,585,865...25,624,280

cellular response to cordycepin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein phosphatase 1 regulatory subunit 15A

cellular response to corticosterone stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP2B1

ATPase plasma membrane Ca2+ transporting 1

NCBI chr11:84,985,957...85,053,923
Ensembl chr11:84,989,169...85,103,957

forkhead box O3

NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725

glutamate ionotropic receptor NMDA type subunit 2B

NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202

lamin B1

NCBI chr23:29,759,133...29,814,332
Ensembl chr23:29,759,514...29,814,314

NPAS4

neuronal PAS domain protein 4

involved_in
acts_upstream_of_or_within

(PMID:20626564)

PMID:20626564

GO_REF:0000107

NCBI chr 1:7,856,222...7,874,812
Ensembl chr 1:7,856,939...7,862,052

cellular response to cortisol stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cytochrome P450 family 1 subfamily B member 1

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

KLF9

KLF transcription factor 9

involved_in

GO_REF:0000107

NCBI chr12:81,451,210...81,481,384
Ensembl chr12:81,454,394...81,480,094

cellular response to curcumin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

glutamate ionotropic receptor NMDA type subunit 2B

NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202

sirtuin 1

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

cellular response to cycloheximide

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KLF2

KLF transcription factor 2

NCBI chr 6:14,832,013...14,834,744
Ensembl chr 6:14,832,029...14,837,462

KLF4

KLF transcription factor 4

NCBI chr12:32,045,690...32,050,531
Ensembl chr12:32,045,609...32,050,703

KLF6

KLF transcription factor 6

NCBI chr 9:3,872,376...3,881,238
Ensembl chr 9:3,875,356...3,881,229

MYC proto-oncogene, bHLH transcription factor

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

serpin family E member 1

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

XRN1

5'-3' exoribonuclease 1

NCBI chr15:48,174,262...48,310,527
Ensembl chr15:48,174,316...48,305,641

cellular response to dehydroepiandrosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

uncoupling protein 1

NCBI chr 7:87,492,444...87,502,894
Ensembl chr 7:87,492,195...87,502,665

cellular response to desipramine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein phosphatase 1 regulatory subunit 15A

cellular response to dexamethasone stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

ATP binding cassette subfamily C member 2

NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265

ATP binding cassette subfamily G member 2 (JR blood group)

NCBI chr 7:36,458,110...36,599,753

AGTR1

angiotensin II receptor type 1

involved_in

PMID:17537984

NCBI chr15:41,957,826...42,002,776

AGTR2

angiotensin II receptor type 2

involved_in

PMID:17537984

aquaporin 1 (Colton blood group)

involved_in

GO_REF:0000107

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

arginase 1

NCBI chr13:41,971,955...41,983,372
Ensembl chr13:41,971,802...41,983,049

arginase 2

NCBI chr24:44,851,139...44,884,118
Ensembl chr24:44,851,175...44,883,853

argininosuccinate lyase

NCBI chr28:1,782,434...1,800,581
Ensembl chr28:1,782,553...1,802,517

argininosuccinate synthase 1

NCBI chr12:7,643,484...7,701,334

ATP5F1A

ATP synthase F1 subunit alpha

NCBI chr18:34,815,924...34,828,052
Ensembl chr18:34,816,027...34,830,924

axin 2

NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281

BCL2 like 1

NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470

BMI1

BMI1 proto-oncogene, polycomb ring finger

NCBI chr 9:22,095,592...22,104,894

bone morphogenetic protein 4

involved_in

PMID:17537984

NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225

CACNA1G

calcium voltage-gated channel subunit alpha1 G

NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843

CASP9

caspase 9

involved_in

(MGI:4456943|PMID:15944155)

PMID:15944155

MGI:4456943

NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930

chromobox 3

NCBI chr21:32,154,707...32,166,843
Ensembl chr21:32,155,839...32,166,114

C-C motif chemokine ligand 2

NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416

cyclin D2

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

CFLAR

CASP8 and FADD like apoptosis regulator

NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652

carboxypeptidase E

NCBI chr 7:111,747,265...111,867,548
Ensembl chr 7:111,747,172...111,868,754

corticotropin releasing hormone

NCBI chr 8:62,052,155...62,056,424
Ensembl chr 8:62,052,592...62,053,182

DDIT4

DNA damage inducible transcript 4

acts_upstream_of_or_within

(PMID:17556672)

NCBI chr 9:59,033,058...59,035,157
Ensembl chr 9:59,032,755...59,035,241

DNA methyltransferase 3 beta

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

DSPP

dentin sialophosphoprotein

NCBI chr 7:35,993,669...35,999,443

epidermal growth factor receptor

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

EIF4E

eukaryotic translation initiation factor 4E

involved_in
acts_upstream_of_or_within

(PMID:17556672)

GO_REF:0000107

NCBI chr 7:47,002,522...47,053,060
Ensembl chr 7:47,001,008...47,051,571

EIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1

acts_upstream_of_or_within

(PMID:17556672)

NCBI chr 8:36,063,311...36,092,439

elastin

NCBI chr28:8,999,164...9,048,703

E1A binding protein p300

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

ERBB receptor feedback inhibitor 1

NCBI chr20:123,738,971...123,753,575
Ensembl chr20:123,738,973...123,755,809

FBXO32

F-box protein 32

acts_upstream_of_or_within

(PMID:23752591)

NCBI chr 8:118,071,856...118,115,761

ferrochelatase

NCBI chr18:22,143,268...22,182,259
Ensembl chr18:22,143,483...22,182,416

forkhead box O1

NCBI chr 3:18,916,849...19,027,776
Ensembl chr 3:18,920,651...19,027,707

GDNF

glial cell derived neurotrophic factor

involved_in

PMID:17537984

NCBI chr 4:36,662,033...36,691,761
Ensembl chr 4:36,665,009...36,684,257

GJB2

gap junction protein beta 2

NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059

HMBS

hydroxymethylbilane synthase

NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095

HNRNPU

heterogeneous nuclear ribonucleoprotein U

NCBI chr25:81,879,532...81,890,684
Ensembl chr25:81,878,111...81,890,701

ICAM1

intercellular adhesion molecule 1

NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263

insulin like growth factor 1

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

insulin like growth factor 1 receptor

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

IGFALS

insulin like growth factor binding protein acid labile subunit

NCBI chr 5:1,698,787...1,704,205
Ensembl chr 5:1,698,978...1,701,972

interleukin 6

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

JAK2

Janus kinase 2

involved_in
acts_upstream_of_or_within

(PMID:21606371)

PMID:21606371

GO_REF:0000107

NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710

L1CAM

L1 cell adhesion molecule

NCBI chr X:128,285,128...128,309,173
Ensembl chr X:128,285,130...128,299,570

LOC103230910

histone-lysine N-methyltransferase SMYD3

acts_upstream_of_or_within

(PMID:23752591)

NCBI chr25:82,794,748...83,531,942

METTL21C

methyltransferase 21C, AARS1 lysine

acts_upstream_of_or_within

(PMID:24677265)

PMID:24677265

NCBI chr 3:81,240,899...81,251,111
Ensembl chr 3:81,241,412...81,250,502

mitofusin 1

NCBI chr15:10,050,616...10,093,118
Ensembl chr15:10,047,599...10,093,126

mitofusin 2

NCBI chr20:119,787,700...119,818,455
Ensembl chr20:119,787,370...119,816,693

MSTN

myostatin

acts_upstream_of_or_within

(PMID:23752591)

NCBI chr10:75,564,816...75,570,956
Ensembl chr10:75,565,152...75,570,528

neurofibromin 1

NCBI chr16:24,550,983...24,836,311
Ensembl chr16:24,550,977...24,836,307

nuclear receptor subfamily 3 group C member 1

involved_in

PMID:12145311

GO_REF:0000107 RGD:729108

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

neurotensin

NCBI chr11:81,270,147...81,278,327
Ensembl chr11:81,270,593...81,277,713

PCK1

phosphoenolpyruvate carboxykinase 1

involved_in

GO_REF:0000118

NCBI chr 2:6,550,806...6,556,499
Ensembl chr 2:6,549,652...6,556,478

PCK2

phosphoenolpyruvate carboxykinase 2, mitochondrial

involved_in

GO_REF:0000118

NCBI chr24:1,077,206...1,087,306
Ensembl chr24:1,077,447...1,087,607

PLAT

plasminogen activator, tissue type

NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555

PNMT

phenylethanolamine N-methyltransferase

NCBI chr16:66,496,290...66,498,840
Ensembl chr16:66,496,027...66,499,111

reelin

NCBI chr21:72,440,988...72,951,173
Ensembl chr21:72,440,160...72,950,747

RPL32

ribosomal protein L32

NCBI chr22:48,811,342...48,816,905
Ensembl chr22:48,811,401...48,816,882

ribosomal protein S6 kinase B1

involved_in
acts_upstream_of_or_within

(PMID:17556672)

GO_REF:0000107

NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453

serpin family E member 1

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

SERPINF1

serpin family F member 1

NCBI chr16:1,408,453...1,424,197

steroid 5 alpha-reductase 1

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

steroidogenic acute regulatory protein

NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583

TBX2

T-box transcription factor 2

NCBI chr16:32,627,296...32,636,797
Ensembl chr16:32,627,819...32,636,880

TFAP4

transcription factor AP-4

involved_in

GO_REF:0000107

NCBI chr 5:3,931,288...3,960,039
Ensembl chr 5:3,932,149...3,954,486

transforming growth factor beta 1

involved_in

PMID:17537984

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

TRIM63

tripartite motif containing 63

acts_upstream_of_or_within

(PMID:23752591)

NCBI chr20:106,676,299...106,714,394
Ensembl chr20:106,703,949...106,716,656

USP8

ubiquitin specific peptidase 8

NCBI chr26:32,829,627...32,906,493
Ensembl chr26:32,829,523...32,866,073

vascular endothelial growth factor A

NCBI chr17:28,377,959...28,394,508

cellular response to dopamine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

dynamin 2

NCBI chr 6:9,718,014...9,830,061
Ensembl chr 6:9,718,244...9,831,206

GNAL

G protein subunit alpha L

NCBI chr18:69,508,254...69,699,628
Ensembl chr18:69,510,512...69,635,000

GSK3B

glycogen synthase kinase 3 beta

NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239

HCN3

hyperpolarization activated cyclic nucleotide gated potassium channel 3

NCBI chr20:8,546,609...8,558,911
Ensembl chr20:8,545,720...8,558,056

histone deacetylase 2

NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742

LOC103230462

sulfotransferase 1A3

involved_in

(PMID:24136195)

PMID:24136195

NCBI chr 5:26,469,450...26,474,416

LOC103247994

DNA-binding protein inhibitor ID-1

NCBI chr 2:36,008,660...36,009,880
Ensembl chr 2:36,008,636...36,010,017

leucine rich repeat kinase 2

involved_in

(PMID:23628791)

ParkinsonsUK-UCL

PMID:23628791

NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216

SIN3A

SIN3 transcription regulator family member A

NCBI chr26:7,971,208...8,060,888
Ensembl chr26:7,975,484...8,058,278

TGM2

transglutaminase 2

involved_in

(PMID:32273471)

PMID:32273471

NCBI chr 2:25,585,827...25,623,961
Ensembl chr 2:25,585,865...25,624,280

cellular response to dsDNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EPG5

ectopic P-granules 5 autophagy tethering factor

involved_in

GO_REF:0000107

NCBI chr18:34,946,778...35,065,449
Ensembl chr18:34,946,796...35,060,595

RIOK3

RIO kinase 3

involved_in

(PMID:24807708)

PMID:24807708

NCBI chr18:57,048,500...57,078,770
Ensembl chr18:57,048,447...57,078,312

cellular response to dsRNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

glutamate ionotropic receptor AMPA type subunit 1

miR-132

NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849

GRIN2A

glutamate ionotropic receptor NMDA type subunit 2A

miR-132

NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828

glutamate ionotropic receptor NMDA type subunit 2B

miR-132

NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202

NFKB1

nuclear factor kappa B subunit 1

involved_in
acts_upstream_of_or_within

(PMID:24114535)

PMID:24114535

GO_REF:0000107

NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498

purinergic receptor P2X 7

acts_upstream_of_or_within

(PMID:24114535)

PMID:24114535

NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059

PDE12

phosphodiesterase 12

involved_in

GO_REF:0000107

NCBI chr22:18,863,676...18,869,778
Ensembl chr22:18,863,696...18,867,736

RIOK3

RIO kinase 3

involved_in

(PMID:24807708)

PMID:24807708

NCBI chr18:57,048,500...57,078,770
Ensembl chr18:57,048,447...57,078,312

cellular response to ergosterol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DYNAP

dynactin associated protein

involved_in

(PMID:20978158)

PMID:20978158

NCBI chr18:25,106,045...25,113,911
Ensembl chr18:25,106,265...25,112,995

cellular response to estradiol stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

ATP binding cassette subfamily G member 2 (JR blood group)

NCBI chr 7:36,458,110...36,599,753

AIFM1

apoptosis inducing factor mitochondria associated 1

NCBI chr X:105,383,408...105,419,146
Ensembl chr X:105,382,693...105,419,095

aquaporin 4

NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156

BCL2 like 11

NCBI chr14:14,178,159...14,205,337

CCDC62

coiled-coil domain containing 62

involved_in

GO_REF:0000107

NCBI chr11:118,112,517...118,166,571
Ensembl chr11:118,113,620...118,163,128

C-C motif chemokine ligand 2

NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416

cyclin A2

NCBI chr 7:69,092,410...69,100,191
Ensembl chr 7:69,093,543...69,099,497

CFLAR

CASP8 and FADD like apoptosis regulator

NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652

CRHBP

corticotropin releasing hormone binding protein

involved_in

(PMID:15345745)
(MGI:5315355|PMID:15345745)

PMID:15345745

MGI:5315355 RGD:8554074

NCBI chr 4:71,203,335...71,223,179
Ensembl chr 4:71,205,932...71,223,172

DEAD-box helicase 18

NCBI chr10:12,455,877...12,473,670
Ensembl chr10:12,457,543...12,473,655

epidermal growth factor receptor

involved_in

GO_REF:0000107

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

NCBI chr 8:114,113,780...114,232,656
Ensembl chr 8:114,113,778...114,195,956

estrogen receptor 1

involved_in

PMID:9448000 PMID:12535528 PMID:15705806 PMID:15831516

(MGI:5825439|PMID:9448000)
PMID:15705806
(PMID:12535528), (PMID:15831516)

UniProt
BHF-UCL

MGI:5825439 RGD:8553914

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

estrogen receptor 2

involved_in

RGD
InterPro

PMID:17928626

GO_REF:0000002 RGD:5128669

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

FAM210B

family with sequence similarity 210 member B

involved_in

(PMID:26968549)

PMID:26968549

NCBI chr 2:7,753,859...7,763,450
Ensembl chr 2:7,756,240...7,763,394

glutaredoxin

NCBI chr 4:89,687,354...89,696,236
Ensembl chr 4:89,685,984...89,696,231

G protein-coupled estrogen receptor 1

involved_in

Ensembl
TreeGrafter
UniProt

GO_REF:0000107 GO_REF:0000117 GO_REF:0000118

NCBI chr28:20,491,874...20,497,966
Ensembl chr28:20,492,188...20,493,315

HNRNPD

heterogeneous nuclear ribonucleoprotein D

NCBI chr 7:30,729,697...30,749,793
Ensembl chr 7:30,731,175...30,749,876

HSD11B1

hydroxysteroid 11-beta dehydrogenase 1

NCBI chr25:19,720,096...19,772,806
Ensembl chr25:19,719,848...19,750,200

heat shock transcription factor 1

NCBI chr 8:138,503,836...138,529,562
Ensembl chr 8:138,503,831...138,529,165

insulin like growth factor 1

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

insulin like growth factor 1 receptor

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

IGFBP3

insulin like growth factor binding protein 3

NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205

interleukin 10

NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836

interleukin 6

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

integrin subunit alpha 2

beta-estradiol

NCBI chr 4:49,280,289...49,382,101
Ensembl chr 4:49,317,648...49,380,051

KAT5

lysine acetyltransferase 5

involved_in

(PMID:23637611)

PMID:23637611

NCBI chr 1:8,528,097...8,544,512
Ensembl chr 1:8,526,788...8,544,972

KIF18A

kinesin family member 18A

NCBI chr 1:37,003,325...37,088,705
Ensembl chr 1:37,003,357...37,088,640

LCOR

ligand dependent nuclear receptor corepressor

involved_in

GO_REF:0000107

NCBI chr 9:90,009,449...90,157,340
Ensembl chr 9:90,152,909...90,156,646

LOC103236032

histone H2A.Z

involved_in

(PMID:23637611)

PMID:23637611

NCBI chr 7:48,079,894...48,082,147

LOC103239432

myoblast determination protein 1

involved_in

GO_REF:0000107

NCBI chr 1:47,250,927...47,254,572
Ensembl chr 1:47,251,551...47,253,284

MMP2

matrix metallopeptidase 2

NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004

MSX2

msh homeobox 2

acts_upstream_of_or_within

(PMID:8787747)

PMID:8787747

NCBI chr23:76,873,499...76,879,935
Ensembl chr23:76,873,669...76,879,553

MYOG

myogenin

involved_in

GO_REF:0000107

NCBI chr25:26,264,872...26,269,652
Ensembl chr25:26,266,717...26,268,867

NCOA3

nuclear receptor coactivator 3

involved_in

(PMID:15831516)

PMID:15831516

NCBI chr 2:16,270,218...16,423,381
Ensembl chr 2:16,273,717...16,423,318

NEFH

neurofilament heavy chain

NCBI chr19:12,357,982...12,375,449

NEFM

neurofilament medium chain

NCBI chr 8:23,039,187...23,044,668
Ensembl chr 8:23,039,282...23,044,667

NRIP1

nuclear receptor interacting protein 1

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 2:77,480,398...77,583,985
Ensembl chr 2:77,577,029...77,580,496

PAWR

pro-apoptotic WT1 regulator

NCBI chr11:75,132,547...75,219,633
Ensembl chr11:75,133,186...75,219,072

POU4F1

POU class 4 homeobox 1

involved_in

(MGI:5825439|PMID:9448000)

PMID:9448000

MGI:5825439

NCBI chr 3:57,667,248...57,673,071

POU4F2

POU class 4 homeobox 2

involved_in

(MGI:5825439|PMID:9448000)

PMID:9448000

MGI:5825439

NCBI chr 7:93,150,105...93,160,977
Ensembl chr 7:93,150,186...93,151,857

PPARG coactivator 1 alpha

NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582

protein phosphatase 1 regulatory subunit 9B

NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680

PTGIS

prostaglandin I2 synthase

NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264

RAMP3

receptor activity modifying protein 3

involved_in

(MGI:5514109|PMID:23674134)

PMID:23674134

MGI:5514109

NCBI chr21:13,494,981...13,521,141

RUVBL2

RuvB like AAA ATPase 2

involved_in

GO_REF:0000107

NCBI chr 6:42,227,982...42,247,204
Ensembl chr 6:42,227,821...42,249,707

secreted frizzled related protein 1

involved_in

GO_REF:0000107

NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984

steroid 5 alpha-reductase 1

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

SSTR1

somatostatin receptor 1

involved_in

PMID:9564833

GO_REF:0000118 RGD:2325004

NCBI chr24:15,000,190...15,006,757
Ensembl chr24:15,003,116...15,004,291

SSTR2

somatostatin receptor 2

involved_in

PMID:9564833

GO_REF:0000118 RGD:2325004

NCBI chr16:48,462,472...48,470,586
Ensembl chr16:48,464,342...48,465,451

SSTR3

somatostatin receptor 3

NCBI chr19:19,908,562...19,916,787
Ensembl chr19:19,910,898...19,912,154

TNFRSF1A

TNF receptor superfamily member 1A

17beta-estradiol

NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902

Wnt family member 4

NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203

ZNF703

zinc finger protein 703

involved_in

GO_REF:0000107

NCBI chr 8:35,730,678...35,735,015
Ensembl chr 8:35,730,736...35,737,788

cellular response to exogenous dsRNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAV1

caveolin 1

involved_in

GO_REF:0000107

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

CGAS

cyclic GMP-AMP synthase

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr17:1,697,446...1,723,626
Ensembl chr17:1,697,775...1,723,472

CIITA

class II major histocompatibility complex transactivator

NCBI chr 5:10,341,690...10,401,988
Ensembl chr 5:10,372,344...10,400,451

COLEC12

collectin subfamily member 12

NOT|involved_in

(PMID:25204797)

UniProt
Ensembl

PMID:25204797

GO_REF:0000107

NCBI chr18:59,701,131...59,884,445
Ensembl chr18:59,699,348...59,884,461

DHX9

DExH-box helicase 9

involved_in

GO_REF:0000107

NCBI chr25:46,485,602...46,534,046
Ensembl chr25:46,485,427...46,518,406

FLOT1

flotillin 1

involved_in

(PMID:25204797)

PMID:25204797

NCBI chr17:41,714,354...41,725,820
Ensembl chr17:41,714,402...41,725,397

IFIH1

interferon induced with helicase C domain 1

involved_in

(PMID:21957149)

PMID:21957149

NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264

IFIT1

interferon induced protein with tetratricopeptide repeats 1

involved_in

GO_REF:0000107

NCBI chr 9:82,778,546...82,797,678
Ensembl chr 9:82,785,898...82,798,621

IRF1

interferon regulatory factor 1

NCBI chr23:35,309,058...35,317,765
Ensembl chr23:35,307,772...35,316,763

IRF3

interferon regulatory factor 3

NCBI chr 6:42,835,285...42,841,487
Ensembl chr 6:42,831,203...42,840,796

MAVS

mitochondrial antiviral signaling protein

involved_in

GO_REF:0000107

NCBI chr 2:34,534,433...34,555,406
Ensembl chr 2:34,541,229...34,552,823

MUL1

mitochondrial E3 ubiquitin protein ligase 1

involved_in

GO_REF:0000107

NCBI chr20:112,042,777...112,051,866
Ensembl chr20:112,042,481...112,052,168

PQBP1

polyglutamine binding protein 1

involved_in

GO_REF:0000107

NCBI chr X:46,014,664...46,020,204
Ensembl chr X:46,015,250...46,023,988

RALB

RAS like proto-oncogene B

involved_in

GO_REF:0000107

NCBI chr10:9,999,828...10,041,158
Ensembl chr10:9,999,904...10,016,473

RIGI

RNA sensor RIG-I

involved_in

(PMID:21957149)

PMID:21957149

NCBI chr12:47,729,040...47,800,995
Ensembl chr12:47,729,076...47,799,570

STING1

stimulator of interferon response cGAMP interactor 1

involved_in

GO_REF:0000107

NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907

TLR3

toll like receptor 3

acts_upstream_of_or_within
involved_in

(PMID:28970238)

PMID:15920723 PMID:20937230 PMID:28970238

GO_REF:0000107 RGD:2301737 RGD:5128701

NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232

ZC3HAV1

zinc finger CCCH-type containing, antiviral 1

acts_upstream_of_or_within

(PMID:21102435)

PMID:21102435

NCBI chr21:107,770,270...107,808,575

ZCCHC3

zinc finger CCHC-type containing 3

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 2:35,422,903...35,426,145
Ensembl chr 2:35,423,430...35,424,638

cellular response to folic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FOLR1

folate receptor alpha

involved_in

GO_REF:0000107

NCBI chr 1:63,405,513...63,413,372
Ensembl chr 1:63,406,597...63,413,352

cellular response to forskolin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY2

adenylate cyclase 2

involved_in

PMID:1719547

NCBI chr 4:6,989,077...7,415,282
Ensembl chr 4:6,989,169...7,414,617

ADCY3

adenylate cyclase 3

involved_in

(MGI:1889935|PMID:11055432)
PMID:24363043

PMID:11055432 PMID:24363043

MGI:1889935 RGD:10400870

NCBI chr14:82,752,786...82,858,727
Ensembl chr14:82,753,177...82,859,415

adenylate cyclase 5

involved_in

(PMID:15385642), (PMID:24700542)

PMID:15385642 PMID:24700542

NCBI chr22:57,427,711...57,589,440

adenylate cyclase 5

involved_in

GO_REF:0000107

Ensembl chr22:57,441,880...57,588,891

ADCY6

adenylate cyclase 6

involved_in

GO_REF:0000107

NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501

ADCY8

adenylate cyclase 8

involved_in

PMID:13680124

NCBI chr 8:125,269,396...125,535,806
Ensembl chr 8:125,269,736...125,533,015

aryl hydrocarbon receptor

involved_in

GO_REF:0000107

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

CFTR

CF transmembrane conductance regulator

involved_in

(PMID:15010471), (PMID:19621064)

PMID:15010471 PMID:19621064

NCBI chr21:86,154,313...86,332,436

cAMP responsive element binding protein 1

involved_in

(PMID:25644539)

NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832

EFNA5

ephrin A5

involved_in
acts_upstream_of_or_within

(PMID:23242526)

PMID:23242526

GO_REF:0000107

NCBI chr23:10,823,243...11,115,175
Ensembl chr23:10,823,261...10,873,666

EPHA5

EPH receptor A5

acts_upstream_of_or_within

(PMID:23242526)

PMID:23242526

NCBI chr 7:3,219,396...3,564,416
Ensembl chr 7:3,219,449...3,559,854

FDX1

ferredoxin 1

involved_in
acts_upstream_of_or_within

(PMID:7495857)

PMID:7495857

GO_REF:0000107

NCBI chr 1:101,777,499...101,813,753
Ensembl chr 1:101,777,678...101,816,379

GNAI1

G protein subunit alpha i1

involved_in

PMID:19703466

NCBI chr21:68,687,809...68,770,415
Ensembl chr21:68,687,307...68,770,360

glutamate ionotropic receptor NMDA type subunit 2B

NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202

HDAC8

histone deacetylase 8

NCBI chr X:62,154,374...62,393,149
Ensembl chr X:62,154,365...62,393,196

HNRNPK

heterogeneous nuclear ribonucleoprotein K

NCBI chr12:94,768,403...94,789,957
Ensembl chr12:94,768,480...94,789,743

PIM3

Pim-3 proto-oncogene, serine/threonine kinase

NCBI chr19:32,466,432...32,470,001
Ensembl chr19:32,466,771...32,470,006

PTGER3

prostaglandin E receptor 3

NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959

SLC5A5

solute carrier family 5 member 5

involved_in

(PMID:9329364)

PMID:9329364

NCBI chr 6:16,346,361...16,367,833

cellular response to genistein

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

thyroglobulin

NCBI chr 8:127,293,797...127,567,218
Ensembl chr 8:127,293,834...127,567,771

UGT3A2

UDP glycosyltransferase family 3 member A2

acts_upstream_of_or_within
involved_in

(PMID:22621930)

PMID:22621930

GO_REF:0000107

NCBI chr 4:34,881,067...34,913,296
Ensembl chr 4:34,882,400...34,912,475

cellular response to glucocorticoid stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACVR1

activin A receptor type 1

NCBI chr10:43,139,396...43,281,024
Ensembl chr10:43,139,528...43,281,177

ADCYAP1

adenylate cyclase activating polypeptide 1

NCBI chr18:60,259,479...60,267,302

aryl hydrocarbon receptor

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

ANXA1

annexin A1

involved_in

GO_REF:0000118

NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562

argininosuccinate lyase

NCBI chr28:1,782,434...1,800,581
Ensembl chr28:1,782,553...1,802,517

CRHR2

corticotropin releasing hormone receptor 2

NCBI chr21:27,703,637...27,738,873
Ensembl chr21:27,708,113...27,739,116

endothelin 1

RU 28362

NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198

epoxide hydrolase 1

NCBI chr25:3,924,396...3,960,264
Ensembl chr25:3,924,606...3,945,535

FAM107A

family with sequence similarity 107 member A

involved_in

(MGI:6162291|PMID:21969592)

PMID:21969592

MGI:6162291

NCBI chr22:19,859,853...19,923,256
Ensembl chr22:19,859,809...19,923,487

FLT3

fms related receptor tyrosine kinase 3

NCBI chr 3:7,117,579...7,222,600
Ensembl chr 3:7,116,947...7,222,849

GSK3A

glycogen synthase kinase 3 alpha

involved_in

(MGI:4818524|PMID:20371704)

PMID:20371704

MGI:4818524

NCBI chr 6:36,434,966...36,447,676
Ensembl chr 6:36,435,578...36,447,633

GSK3B

glycogen synthase kinase 3 beta

involved_in

(MGI:4818524|PMID:20371704)

PMID:20371704

MGI:4818524

NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239

GSTP1

glutathione S-transferase pi 1

NCBI chr 1:6,676,897...6,679,936

HEY1

hes related family bHLH transcription factor with YRPW motif 1

NCBI chr 8:75,225,081...75,228,941
Ensembl chr 8:75,224,769...75,228,896

3-hydroxy-3-methylglutaryl-CoA synthase 2

hydrocortisone

NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016

HNRNPU

heterogeneous nuclear ribonucleoprotein U

involved_in

GO_REF:0000107

NCBI chr25:81,879,532...81,890,684
Ensembl chr25:81,878,111...81,890,701

interleukin 17A

NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785

ISL1

ISL LIM homeobox 1

involved_in

PMID:19619559

NCBI chr 4:47,665,861...47,678,631
Ensembl chr 4:47,666,536...47,677,552

LOC103218970

alpha-1-acid glycoprotein 1

NCBI chr12:25,257,002...25,261,255
Ensembl chr12:25,256,969...25,260,446

LOC103225759

somatostatin receptor type 5

involved_in

PMID:14512709

GO_REF:0000118 RGD:2325001

NCBI chr 5:967,785...976,353
Ensembl chr 5:973,791...974,885

LOC103239432

myoblast determination protein 1

involved_in
acts_upstream_of_or_within

(PMID:19319192)

PMID:19319192

GO_REF:0000107

NCBI chr 1:47,250,927...47,254,572
Ensembl chr 1:47,251,551...47,253,284

MHC-DQA1

major histocompatibility complex, class II, DQ alpha 1

NCBI chr17:39,422,445...39,428,777
Ensembl chr17:39,420,134...39,428,871

MUC5AC

mucin 5AC, oligomeric mucus/gel-forming

NCBI chr 1:981,515...1,018,242

nuclear receptor subfamily 3 group C member 1

involved_in

GO_REF:0000107

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

REST

RE1 silencing transcription factor

involved_in

GO_REF:0000107

NCBI chr 7:11,749,312...11,776,103
Ensembl chr 7:11,749,168...11,773,340

SSTR2

somatostatin receptor 2

involved_in

PMID:14512709

GO_REF:0000118 RGD:2325001

NCBI chr16:48,462,472...48,470,586
Ensembl chr16:48,464,342...48,465,451

SSTR3

somatostatin receptor 3

NCBI chr19:19,908,562...19,916,787
Ensembl chr19:19,910,898...19,912,154

SSTR4

somatostatin receptor 4

involved_in

PMID:14512709

GO_REF:0000118 RGD:2325001

NCBI chr 2:52,027,241...52,034,777
Ensembl chr 2:52,031,021...52,032,187

stanniocalcin 1

NCBI chr 8:21,975,286...21,988,182
Ensembl chr 8:21,975,283...21,988,198

UBE2L3

ubiquitin conjugating enzyme E2 L3

involved_in

(PMID:17003263)

PMID:17003263

NCBI chr19:4,485,960...4,538,838

urocortin 2

NCBI chr22:9,962,339...9,964,553

ZFP36

ZFP36 ring finger protein

involved_in

GO_REF:0000107

NCBI chr 6:34,011,073...34,013,665
Ensembl chr 6:34,011,031...34,013,870

ZFP36L1

ZFP36 ring finger protein like 1

involved_in

(PMID:20166898)

PMID:20166898

NCBI chr24:46,000,222...46,005,455
Ensembl chr24:45,999,623...46,006,218

ZFP36L2

ZFP36 ring finger protein like 2

involved_in

GO_REF:0000107

NCBI chr14:64,019,633...64,022,301
Ensembl chr14:64,019,418...64,026,281

ZNF764

zinc finger protein 764

involved_in

GO_REF:0000107

cellular response to histamine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DIAPH1

diaphanous related formin 1

involved_in

GO_REF:0000107

NCBI chr23:44,139,495...44,244,505
Ensembl chr23:44,139,360...44,244,490

FGFR1

fibroblast growth factor receptor 1

NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508

GABRA1

gamma-aminobutyric acid type A receptor subunit alpha1

involved_in

PMID:18281286

NCBI chr23:64,199,372...64,255,996
Ensembl chr23:64,200,752...64,255,996

GABRB1

gamma-aminobutyric acid type A receptor subunit beta1

involved_in

PMID:18281286

NCBI chr27:2,829,385...3,254,292
Ensembl chr27:2,832,450...3,217,326

GABRB2

gamma-aminobutyric acid type A receptor subunit beta2

involved_in

PMID:18281286

NCBI chr23:63,636,094...63,894,587
Ensembl chr23:63,637,109...63,893,370

GABRB3

gamma-aminobutyric acid type A receptor subunit beta3

involved_in

GO_REF:0000107

NCBI chr26:55,319,667...55,543,116
Ensembl chr26:55,471,907...55,538,855

GABRG2

gamma-aminobutyric acid type A receptor subunit gamma2

involved_in

GO_REF:0000107

NCBI chr23:64,422,519...64,512,124
Ensembl chr23:64,422,391...64,513,652

HRH2

histamine receptor H2

NCBI chr23:77,808,108...77,858,936
Ensembl chr23:77,807,998...77,841,467

cellular response to indole-3-methanol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BRCA1 DNA repair associated

involved_in

(PMID:10868478)

PMID:10868478

NCBI chr16:63,162,827...63,243,928

CTNNA1

catenin alpha 1

involved_in

GO_REF:0000107

NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190

CTNNB1

catenin beta 1

involved_in

GO_REF:0000107

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

JUP

junction plakoglobin

involved_in

GO_REF:0000107

NCBI chr16:64,470,974...64,503,085
Ensembl chr16:64,470,959...64,503,322

LOC103233229

cadherin-1

involved_in

GO_REF:0000107

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

cellular response to ionomycin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDK4

cyclin dependent kinase 4

acts_upstream_of_or_within

(PMID:8543804)

PMID:8543804

NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861

forkhead box P1

NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502

NFATC4

nuclear factor of activated T cells 4

NCBI chr24:1,352,173...1,362,150
Ensembl chr24:1,352,291...1,362,680

PLCB1

phospholipase C beta 1

NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793

PPARG coactivator 1 alpha

NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582

ZC3H12A

zinc finger CCCH-type containing 12A

involved_in

GO_REF:0000107

NCBI chr20:95,388,469...95,398,305
Ensembl chr20:95,388,477...95,397,960

ZNF683

zinc finger protein 683

involved_in

(PMID:26179882)

PMID:26179882

NCBI chr20:106,336,441...106,411,217

cellular response to isoquinoline alkaloid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

early growth response 1

berberine

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

methyl-CpG binding protein 2

bicuculline

NCBI chr X:128,445,028...128,519,892
Ensembl chr X:128,453,577...128,455,785

cellular response to kainic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EPOR

erythropoietin receptor

NCBI chr 6:10,313,382...10,320,196
Ensembl chr 6:10,313,775...10,320,066

cellular response to L-ascorbic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

elastin

NCBI chr28:8,999,164...9,048,703

leptin

NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220

cellular response to L-dopa

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAPGEF3

Rap guanine nucleotide exchange factor 3

NCBI chr11:43,954,517...43,979,068
Ensembl chr11:43,957,425...43,978,047

cellular response to leptomycin B

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ID3

inhibitor of DNA binding 3, HLH protein

acts_upstream_of_or_within

(PMID:23523789)

PMID:23523789

NCBI chr20:109,120,403...109,122,269
Ensembl chr20:109,120,691...109,123,210

OAZ1

ornithine decarboxylase antizyme 1

NCBI chr 6:2,061,774...2,065,595
Ensembl chr 6:2,061,811...2,065,265

RANBP1

RAN binding protein 1

NCBI chr19:5,611,968...5,622,414
Ensembl chr19:5,612,268...5,622,191

cellular response to mineralocorticoid stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

endothelin 1

aldosterone

NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198

E1A binding protein p300

11-deoxycorticosterone

PMID:22465009

RGD:7327218

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

G protein-coupled estrogen receptor 1

involved_in

PMID:23283935

NCBI chr28:20,491,874...20,497,966
Ensembl chr28:20,492,188...20,493,315

RAN

RAN, member RAS oncogene family

aldosterone

NCBI chr11:126,257,849...126,263,481

cellular response to morphine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY8

adenylate cyclase 8

involved_in

GO_REF:0000107

NCBI chr 8:125,269,396...125,535,806
Ensembl chr 8:125,269,736...125,533,015

AIF1

allograft inflammatory factor 1

morphine

autophagy related 7

NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070

C-C motif chemokine ligand 5

NCBI chr16:29,351,214...29,361,317

KCNJ6

potassium inwardly rectifying channel subfamily J member 6

NCBI chr 2:81,569,659...81,878,047

OPRM1

opioid receptor mu 1

involved_in

GO_REF:0000108

NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088

protein phosphatase 1 regulatory subunit 9B

involved_in

GO_REF:0000107

NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680

PTK2

protein tyrosine kinase 2

NCBI chr 8:134,897,511...135,246,300

cellular response to mycophenolic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

early growth response 1

involved_in

PMID:18723570

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

PDGFB

platelet derived growth factor subunit B

involved_in

PMID:18723570

NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395

cellular response to norepinephrine stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APLP1

amyloid beta precursor like protein 1

involved_in

(PMID:16531006)

PMID:16531006

NCBI chr 6:30,780,112...30,791,582
Ensembl chr 6:30,780,085...30,791,636

APP

amyloid beta precursor protein

NCBI chr 2:66,037,224...66,320,860
Ensembl chr 2:66,037,261...66,321,306

brain derived neurotrophic factor

NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336

CCN1

cellular communication network factor 1

NCBI chr20:47,783,270...47,786,216
Ensembl chr20:47,783,935...47,785,997

IL1RN

interleukin 1 receptor antagonist

NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326

cellular response to organic cyclic compound

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGER

advanced glycosylation end-product specific receptor

antioxidant Trolox

NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127

AKT1

AKT serine/threonine kinase 1

NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698

AKT2

AKT serine/threonine kinase 2

Okadaic acid

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

5'-aminolevulinate synthase 1

heme

NCBI chr22:13,558,011...13,573,740
Ensembl chr22:13,559,180...13,575,869

alkaline phosphatase, biomineralization associated

involved_in
acts_upstream_of_or_within

(PMID:15728361)

PMID:15728361

GO_REF:0000107

NCBI chr20:111,055,583...111,124,143
Ensembl chr20:111,055,558...111,081,850

ANKRD1

ankyrin repeat domain 1

doxorubicin

NCBI chr 9:84,248,133...84,257,276
Ensembl chr 9:84,247,241...84,257,170

ARHGDIA

Rho GDP dissociation inhibitor alpha

haloperidol, risperidone, or clozapine

PMID:22960606

RGD:9684960

NCBI chr16:73,741,402...73,745,079
Ensembl chr16:73,740,944...73,745,062

ARL6IP5

ADP ribosylation factor like GTPase 6 interacting protein 5

acts_upstream_of_or_within
involved_in

(PMID:12562531)

PMID:12562531

GO_REF:0000107

NCBI chr22:30,110,881...30,132,186
Ensembl chr22:30,111,017...30,135,240

AXIN2

axin 2

polychlorinated biphenyl

PMID:19464575

RGD:4107035

NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281

BRCA1 associated RING domain 1

Loperamide

NCBI chr10:100,539,827...100,627,718
Ensembl chr10:100,539,527...100,627,675

BCL2 apoptosis regulator

liquiritigenin

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

BMP2

bone morphogenetic protein 2

involved_in
acts_upstream_of_or_within

(PMID:19103752)

GO_REF:0000107

NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901

BTRC

beta-transducin repeat containing E3 ubiquitin protein ligase

acts_upstream_of_or_within

(PMID:19103752)

NCBI chr 9:94,333,046...94,581,327
Ensembl chr 9:94,376,055...94,574,678

bystin like

forskolin

NCBI chr17:30,230,001...30,241,684
Ensembl chr17:30,230,337...30,241,417

CASP3

caspase 3

n-butylidenephthalide

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

CASP8

caspase 8

n-butylidenephthalide

NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829

CASP9

caspase 9

n-butylidenephthalide

NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930

cyclin A2

NCBI chr 7:69,092,410...69,100,191
Ensembl chr 7:69,093,543...69,099,497

CCNB1

cyclin B1

antitumorigenic flavonoid chalcone isoliquiritigenin

PMID:19298190

RGD:2316316

NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085

CDK1

cyclin dependent kinase 1

roscovitine

NCBI chr 9:70,475,736...70,492,947

CDKN1B

cyclin dependent kinase inhibitor 1B

acts_upstream_of_or_within

(PMID:19056892)

PMID:19056892

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

CEBPA

CCAAT enhancer binding protein alpha

acts_upstream_of_or_within

(PMID:12055200)

NCBI chr 6:28,342,506...28,345,759
Ensembl chr 6:28,343,907...28,344,977

CEBPB

CCAAT enhancer binding protein beta

epigallocatechin

NCBI chr 2:13,780,538...13,782,639
Ensembl chr 2:13,781,160...13,782,194

cytochrome P450 family 1 subfamily A member 1

acts_upstream_of_or_within
involved_in

(PMID:23275542)

PMID:23275542

GO_REF:0000107

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

cytochrome P450 family 1 subfamily B member 1

acts_upstream_of_or_within
involved_in

(PMID:23275542)

PMID:23275542

GO_REF:0000107

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

CYP2C19

cytochrome P450 family 2 subfamily C member 19

NCBI chr 9:87,981,300...88,025,007

DAG1

dystroglycan 1

involved_in
acts_upstream_of_or_within

(PMID:24753587)

PMID:24753587

GO_REF:0000107

NCBI chr22:10,864,058...10,934,179
Ensembl chr22:10,865,724...10,934,200

elastin

NCBI chr28:8,999,164...9,048,703

E1A binding protein p300

curcumin

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

ERCC4

ERCC excision repair 4, endonuclease catalytic subunit

1-Methyl-4-phenyl-pyridinium

PMID:20101267

RGD:10401089

NCBI chr 5:13,378,282...13,410,307
Ensembl chr 5:13,378,401...13,406,541

estrogen receptor 2

naringin

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

ferredoxin 1

forskolin

NCBI chr 1:101,777,499...101,813,753
Ensembl chr 1:101,777,678...101,816,379

FGA

fibrinogen alpha chain

12-O-tetradecanoylphorbol-13-acetate

PMID:2440878

RGD:9685037

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

FOXF1

forkhead box F1

involved_in
acts_upstream_of_or_within

(PMID:18421012)

PMID:18421012

GO_REF:0000107

NCBI chr 5:71,898,473...71,902,624
Ensembl chr 5:71,898,786...71,903,661

GLI2

GLI family zinc finger 2

acts_upstream_of_or_within

(PMID:19103752)

NCBI chr10:9,302,890...9,561,287
Ensembl chr10:9,304,645...9,369,115

glutamate ionotropic receptor AMPA type subunit 1

sigma-1 receptor agonist SA4503

PMID:20025928

RGD:4107360

NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849

glutamate ionotropic receptor NMDA type subunit 2B

hydroxysafflor yellow A

PMID:20526740

RGD:2325861

NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202

G protein-coupled receptor kinase 2

chelerythrine

NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259

GSK3A

glycogen synthase kinase 3 alpha

acts_upstream_of_or_within

(PMID:12055200)

NCBI chr 6:36,434,966...36,447,676
Ensembl chr 6:36,435,578...36,447,633

HAND2

heart and neural crest derivatives expressed 2

doxorubicin

NCBI chr 7:119,635,697...119,639,415
Ensembl chr 7:119,634,741...119,638,546

host cell factor C1

NCBI chr X:128,371,518...128,395,920
Ensembl chr X:128,371,517...128,394,861

hypoxia inducible factor 1 subunit alpha

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

3-hydroxy-3-methylglutaryl-CoA synthase 1

cafestol

NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409

3-hydroxy-3-methylglutaryl-CoA synthase 2

5-azacytidine

NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016

HSD17B4

hydroxysteroid 17-beta dehydrogenase 4

mono-(2-ethylhexyl) phthalate

PMID:12706301

RGD:10411897

NCBI chr23:22,674,059...22,761,270
Ensembl chr23:22,674,072...22,762,056

heat shock transcription factor 1

Z-ligustilide

NCBI chr 8:138,503,836...138,529,562
Ensembl chr 8:138,503,831...138,529,165

HSP90AB1

heat shock protein 90 alpha family class B member 1

guanylate cyclase inhibitor LY83583

PMID:10617604

RGD:1304537

NCBI chr17:27,914,261...27,921,666
Ensembl chr17:27,911,013...27,921,251

IGFBP5

insulin like growth factor binding protein 5

involved_in

(PMID:7559606)

PMID:7559606

NCBI chr10:102,510,939...102,531,710
Ensembl chr10:102,510,897...102,531,724

inhibin subunit beta B

beta-phorbol 12-myristate 13-acetate

PMID:1634019

RGD:9743923

NCBI chr10:9,943,015...9,948,721

integrin subunit alpha 2

mifeprisone

NCBI chr 4:49,280,289...49,382,101
Ensembl chr 4:49,317,648...49,380,051

ITGA6

integrin subunit alpha 6

phorbolmyristate acetate

PMID:13130099

RGD:1302259

NCBI chr10:57,933,434...58,013,152
Ensembl chr10:57,933,535...58,014,170

KEAP1

kelch like ECH associated protein 1

tert-Butylhydroquinone

PMID:11439354

RGD:727319

NCBI chr 6:9,515,789...9,526,699
Ensembl chr 6:9,515,416...9,522,797

KLF2

KLF transcription factor 2

U0126, LY294002

NCBI chr 6:14,832,013...14,834,744
Ensembl chr 6:14,832,029...14,837,462

KLF4

KLF transcription factor 4

U0126, LY294002

NCBI chr12:32,045,690...32,050,531
Ensembl chr12:32,045,609...32,050,703

KLF5

KLF transcription factor 5

U0126

NCBI chr 3:52,188,139...52,210,882

KLF6

KLF transcription factor 6

U0126

NCBI chr 9:3,872,376...3,881,238
Ensembl chr 9:3,875,356...3,881,229

LGALS1

galectin 1

3,3',4,4',5-pentachlorobiphenyl

PMID:17316808

RGD:2316540

NCBI chr19:20,379,144...20,383,303
Ensembl chr19:20,379,003...20,383,464

LMNB1

lamin B1

2,3,7,8-tetrachlorodibenzodioxine

PMID:16548065

RGD:10045607

NCBI chr23:29,759,133...29,814,332
Ensembl chr23:29,759,514...29,814,314

LOC103233451

cytochrome b-245 light chain

NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750

leucine rich repeat kinase 2

NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216

MBD2

methyl-CpG binding domain protein 2

serotonin

NCBI chr18:26,714,610...26,785,028

MDM2

MDM2 proto-oncogene

delta-9-tetrahydrocannabinol; p72Mdm2

PMID:19819240

RGD:2317362

NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890

MEF2C

myocyte enhancer factor 2C

doxorubicin

NCBI chr 4:82,702,378...82,887,491
Ensembl chr 4:82,706,738...82,788,152

MGMT

O-6-methylguanine-DNA methyltransferase

antiproliferative emodin

PMID:19549930

RGD:2315566

NCBI chr 9:122,089,768...122,376,320

mutL homolog 1

deoxycholic acid

NCBI chr15:2,364,537...2,418,379
Ensembl chr15:2,364,738...2,418,393

MMP1

matrix metallopeptidase 1

Cxcr3 antagonist AMG487

PMID:21811993

RGD:7207285

NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767

MSR1

macrophage scavenger receptor 1

NCBI chr 8:14,221,389...14,305,059
Ensembl chr 8:14,220,529...14,304,946

MYC proto-oncogene, bHLH transcription factor

estrogen receptor antagonist ICI 182780

PMID:21980073

RGD:7241005

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

NAGLU

N-acetyl-alpha-glucosaminidase

involved_in
acts_upstream_of_or_within

(PMID:21037080)

PMID:21037080

GO_REF:0000107

NCBI chr16:63,735,411...63,744,365

NFKB1

nuclear factor kappa B subunit 1

acts_upstream_of_or_within

PMID:19414010

NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498

NFKBIA

NFKB inhibitor alpha

acts_upstream_of_or_within

PMID:19414010

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

NOD2

nucleotide binding oligomerization domain containing 2

baicalin

NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499

nitric oxide synthase 2

acts_upstream_of_or_within

PMID:19414010

NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257

nitric oxide synthase 3

chenodeoxycholic acid

PMID:18006476

RGD:7777115

NCBI chr21:119,174,829...119,196,840

OAZ1

ornithine decarboxylase antizyme 1

Lactacystin

NCBI chr 6:2,061,774...2,065,595
Ensembl chr 6:2,061,811...2,065,265

purinergic receptor P2X 7

acts_upstream_of_or_within

(PMID:23479225)

NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059

P2RY1

purinergic receptor P2Y1

acts_upstream_of_or_within

(PMID:23479225)

NCBI chr15:37,822,474...37,827,245

P2RY12

purinergic receptor P2Y12

acts_upstream_of_or_within

(PMID:23479225)

NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637

P2RY13

purinergic receptor P2Y13

involved_in
acts_upstream_of_or_within

(PMID:23479225)

GO_REF:0000107

NCBI chr15:39,368,984...39,372,731
Ensembl chr15:39,369,458...39,373,014

P2RY6

pyrimidinergic receptor P2Y6

involved_in
acts_upstream_of_or_within

(PMID:23479225)

GO_REF:0000107

NCBI chr 1:64,508,959...64,543,302
Ensembl chr 1:64,541,221...64,542,207

PAK1

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

(PMID:23509247)

NCBI chr 1:68,530,037...68,679,413
Ensembl chr 1:68,529,571...68,617,092

PAK2

p21 (RAC1) activated kinase 2

involved_in
acts_upstream_of_or_within

(PMID:23509247)

GO_REF:0000107

NCBI chr15:90,474,367...90,488,814
Ensembl chr15:90,398,660...90,449,346
Ensembl chr15:90,398,660...90,449,346

PAK3

p21 (RAC1) activated kinase 3

acts_upstream_of_or_within

(PMID:23509247)

NCBI chr X:98,743,525...99,031,056
Ensembl chr X:98,911,447...99,027,769

PAK4

p21 (RAC1) activated kinase 4

involved_in
acts_upstream_of_or_within

(PMID:23509247)

GO_REF:0000107

NCBI chr 6:33,715,695...33,769,272
Ensembl chr 6:33,759,462...33,770,497

PECAM1

platelet and endothelial cell adhesion molecule 1

chlorogenic acid

NCBI chr16:56,863,763...56,947,479
Ensembl chr16:56,880,934...56,950,999

PLA2G4F

phospholipase A2 group IVF

involved_in
acts_upstream_of_or_within

(PMID:17293613)

PMID:17293613

GO_REF:0000107

NCBI chr26:40,835,777...40,852,021
Ensembl chr26:40,836,266...40,852,054

peroxisome proliferator activated receptor gamma

acts_upstream_of_or_within

(PMID:12055200)

NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418

protein phosphatase 1 regulatory subunit 15A

thapsigargin

protein phosphatase 1 regulatory subunit 9B

Faslodex

NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680

pleiotrophin

D-galactosamine

NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215

RAE1

ribonucleic acid export 1

acts_upstream_of_or_within

(PMID:11567106)

PMID:11567106

NCBI chr 2:6,744,984...6,772,870
Ensembl chr 2:6,744,982...6,772,736

RAP1A

RAP1A, member of RAS oncogene family

forskolin

NCBI chr20:21,895,829...21,989,008
Ensembl chr20:21,899,669...21,917,350

RAP1B

RAP1B, member of RAS oncogene family

forskolin

NCBI chr11:64,240,501...64,290,515
Ensembl chr11:64,240,651...64,286,727

RAPGEF3

Rap guanine nucleotide exchange factor 3

cAMP analog 8CPT-2Me-cAMP

PMID:18276108

RGD:9835371

NCBI chr11:43,954,517...43,979,068
Ensembl chr11:43,957,425...43,978,047

ribosomal protein S6 kinase B1

involved_in
acts_upstream_of_or_within

(PMID:24990923)

PMID:24990923

GO_REF:0000107

NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453

serpin family E member 1

UTP
ionomycin

PMID:15961275 PMID:20471392

RGD:8547726 RGD:8547860

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

sirtuin 1

1-methyl-4-phenylpyridinium

PMID:18538940

RGD:9586004

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

SLC16A1

solute carrier family 16 member 1

anion exchange inhibitor 4,4'-diisothiocyano-2,2'-stilbenedisulfonic acid (DIDS)

PMID:19473976

RGD:7242735

NCBI chr20:20,694,222...20,741,542
Ensembl chr20:20,727,199...20,739,979

solute carrier family 1 member 1

acts_upstream_of_or_within

(PMID:12562531)

PMID:12562531

NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369

SLC2A2

solute carrier family 2 member 2

NCBI chr15:18,434,370...18,466,331
Ensembl chr15:18,434,916...18,467,352

SLC9A1

solute carrier family 9 member A1

compound C

NCBI chr20:105,613,289...105,670,868
Ensembl chr20:105,613,338...105,674,208

SMAD1

SMAD family member 1

involved_in
acts_upstream_of_or_within

(PMID:19103752)

GO_REF:0000107

NCBI chr 7:92,047,273...92,123,451
Ensembl chr 7:92,079,914...92,123,429

SMAD5

SMAD family member 5

acts_upstream_of_or_within

(PMID:19103752)

NCBI chr23:38,877,294...38,926,208
Ensembl chr23:38,877,315...38,921,202

SMAD9

SMAD family member 9

acts_upstream_of_or_within

(PMID:19103752)

NCBI chr 3:15,369,119...15,444,599
Ensembl chr 3:15,372,933...15,405,836

SOCS1

suppressor of cytokine signaling 1

acts_upstream_of_or_within

PMID:19414010

NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991

SP5

Sp5 transcription factor

involved_in
acts_upstream_of_or_within

(PMID:25535395)

PMID:25535395

GO_REF:0000107

NCBI chr10:56,244,579...56,247,770
Ensembl chr10:56,245,295...56,247,186

steroid 5 alpha-reductase 1

ketanserin, in serotonin-treated C6 glioma cells

PMID:15936112

RGD:4891926

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

steroidogenic acute regulatory protein

adenosine

NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583

signal transducer and activator of transcription 1

acts_upstream_of_or_within

PMID:19414010

NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393

STAT3

signal transducer and activator of transcription 3

acts_upstream_of_or_within

PMID:19414010

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

STAT4

signal transducer and activator of transcription 4

acts_upstream_of_or_within

PMID:19414010

NCBI chr10:76,553,626...76,708,540
Ensembl chr10:76,553,606...76,674,928

STAT5A

signal transducer and activator of transcription 5A

acts_upstream_of_or_within

PMID:19414010

NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026

STING1

stimulator of interferon response cGAMP interactor 1

involved_in

GO_REF:0000107

NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907

TIPARP

TCDD inducible poly(ADP-ribose) polymerase

acts_upstream_of_or_within
involved_in

(PMID:23275542)

PMID:23275542

GO_REF:0000107

NCBI chr15:34,041,208...34,073,428
Ensembl chr15:34,039,657...34,073,319

TMF1

TATA element modulatory factor 1

involved_in
acts_upstream_of_or_within

(PMID:22531781)

PMID:22531781

GO_REF:0000107

NCBI chr22:30,048,269...30,078,600
Ensembl chr22:30,045,685...30,078,414

WNT10B

Wnt family member 10B

acts_upstream_of_or_within

(PMID:19723499)

PMID:19723499

NCBI chr11:45,205,728...45,229,050
Ensembl chr11:45,205,566...45,210,893

cellular response to progesterone stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACOD1

aconitate decarboxylase 1

involved_in

(MGI:5488888|PMID:14500577)

PMID:14500577

MGI:5488888

NCBI chr 3:56,037,628...56,048,509
Ensembl chr 3:56,042,149...56,047,680

cytochrome P450 family 1 subfamily B member 1

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

insulin like growth factor 1

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

insulin like growth factor 1 receptor

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

SOX10

SRY-box transcription factor 10

NCBI chr19:20,673,053...20,685,506

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

PMID:21440892

NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776

TRERF1

transcriptional regulating factor 1

involved_in

(PMID:17015480)

PMID:17015480

NCBI chr17:29,700,505...29,927,247
Ensembl chr17:29,883,231...29,927,388

VPS54

VPS54 subunit of GARP complex

involved_in

(PMID:22486171)

PMID:22486171

NCBI chr14:43,000,960...43,127,129
Ensembl chr14:43,008,915...43,125,850

cellular response to purine-containing compound

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

P2RY1

purinergic receptor P2Y1

involved_in

(PMID:9442040)

PMID:9442040

NCBI chr15:37,822,474...37,827,245

P2RY2

purinergic receptor P2Y2

NCBI chr 1:64,461,929...64,481,429
Ensembl chr 1:64,479,642...64,480,775

P2RY6

pyrimidinergic receptor P2Y6

involved_in

GO_REF:0000107

NCBI chr 1:64,508,959...64,543,302
Ensembl chr 1:64,541,221...64,542,207

TRPM2

transient receptor potential cation channel subfamily M member 2

involved_in

(MGI:5298324|PMID:21753080)

PMID:21753080

MGI:5298324

NCBI chr 2:88,082,391...88,170,340
Ensembl chr 2:88,087,448...88,170,344

cellular response to puromycin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

XRN1

5'-3' exoribonuclease 1

NCBI chr15:48,174,262...48,310,527
Ensembl chr15:48,174,316...48,305,641

cellular response to pyrimidine ribonucleotide

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTR3

actin related protein 3

NCBI chr10:16,296,350...16,369,561
Ensembl chr10:16,297,502...16,369,220

P2RY6

pyrimidinergic receptor P2Y6

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:64,508,959...64,543,302
Ensembl chr 1:64,541,221...64,542,207

cellular response to rapamycin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARPC2

actin related protein 2/3 complex subunit 2

NCBI chr10:104,098,275...104,144,043
Ensembl chr10:104,098,402...104,135,791

GOLPH3

golgi phosphoprotein 3

involved_in

GO_REF:0000107

NCBI chr 4:31,408,297...31,461,539
Ensembl chr 4:31,409,386...31,461,547

G protein-coupled receptor kinase 2

NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259

HNF1 homeobox A

NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751

HNRNPK

heterogeneous nuclear ribonucleoprotein K

NCBI chr12:94,768,403...94,789,957
Ensembl chr12:94,768,480...94,789,743

LARP1

La ribonucleoprotein 1, translational regulator

involved_in

GO_REF:0000107

NCBI chr23:57,126,878...57,265,243
Ensembl chr23:57,238,336...57,261,710

Nanog homeobox

NCBI chr11:7,813,309...7,820,009

cellular response to resveratrol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aldehyde dehydrogenase 2 family member

protein:altered expression, altered activity:liver (rat)

PMID:28688179

RGD:14981582

NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374

PPARG coactivator 1 alpha

NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582

serpin family E member 1

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

sirtuin 1

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

cellular response to rotenone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nitric oxide synthase 3

NCBI chr21:119,174,829...119,196,840

sirtuin 1

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

cellular response to serotonin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HTR2B

5-hydroxytryptamine receptor 2B

NCBI chr10:117,132,919...117,152,132
Ensembl chr10:117,133,195...117,149,681

neuregulin 1

NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487

TGM2

transglutaminase 2

involved_in

(PMID:30867594)

PMID:30867594

NCBI chr 2:25,585,827...25,623,961
Ensembl chr 2:25,585,865...25,624,280

cellular response to staurosporine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CASP3

caspase 3

involved_in

GO_REF:0000107

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

CASP6

caspase 6

involved_in

GO_REF:0000107

NCBI chr 7:57,592,632...57,616,094
Ensembl chr 7:57,593,342...57,607,489

CASP7

caspase 7

involved_in

GO_REF:0000107

NCBI chr 9:106,558,291...106,607,662
Ensembl chr 9:106,559,445...106,607,663

carboxypeptidase E

NCBI chr 7:111,747,265...111,867,548
Ensembl chr 7:111,747,172...111,868,754

MTRNR2L5

MT-RNR2 like 5

involved_in

(PMID:19477263)

PMID:19477263

NCBI chr 9:75,664,365...75,666,481

PLAU

plasminogen activator, urokinase

NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286

SLC34A1

solute carrier family 34 member 1

NCBI chr23:79,395,923...79,410,835
Ensembl chr23:79,396,250...79,411,695

cellular response to steroid hormone stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADTRP

androgen dependent TFPI regulating protein

involved_in

(PMID:21868574)

PMID:21868574

NCBI chr17:60,371,412...60,436,988
Ensembl chr17:60,368,546...60,438,864

androgen receptor

involved_in

PMID:2341409 PMID:12902338

methyltrienolone
(PMID:12902338)

RGD
CAFA

RGD:1298681

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

ATP1A1

ATPase Na+/K+ transporting subunit alpha 1

involved_in

GO_REF:0000107

NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054

ATP1A2

ATPase Na+/K+ transporting subunit alpha 2

involved_in

(MGI:3608241|PMID:16243970)
PMID:17442282
(PMID:14742675)

PMID:14742675 PMID:16243970 PMID:17442282

MGI:3608241 RGD:6903343

NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692

early growth response 1

pregnenolone

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

mediator complex subunit 1

involved_in

GO_REF:0000107

NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896

MGARP

mitochondria localized glutamic acid rich protein

involved_in

(MGI:5426348|PMID:20107910)

PMID:20107910

MGI:5426348

NCBI chr 7:86,233,666...86,246,218
Ensembl chr 7:86,233,448...86,245,975

NKX3-1

NK3 homeobox 1

involved_in

(PMID:19886863)

PMID:19886863

NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319

NPC1

NPC intracellular cholesterol transporter 1

acts_upstream_of_or_within

(PMID:10787428)

PMID:10787428

NCBI chr18:56,956,557...57,007,951
Ensembl chr18:56,956,174...57,007,474

nuclear receptor subfamily 3 group C member 1

involved_in

GO_REF:0000107

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

PPP2CA

protein phosphatase 2 catalytic subunit alpha

dehydroepiandrosterone

PMID:18079279

RGD:8693668

NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280

TFPI

tissue factor pathway inhibitor

involved_in

(PMID:21868574)

PMID:21868574

NCBI chr10:73,004,762...73,105,772
Ensembl chr10:73,002,522...73,105,858

UBE2L3

ubiquitin conjugating enzyme E2 L3

involved_in

(PMID:15367689)

PMID:15367689

NCBI chr19:4,485,960...4,538,838

URI1

URI1 prefoldin like chaperone

involved_in

GO_REF:0000107

NCBI chr 6:25,005,512...25,078,054
Ensembl chr 6:25,005,316...25,078,541

cellular response to sterol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

INSIG1

insulin induced gene 1

involved_in

GO_REF:0000107

NCBI chr21:123,448,614...123,460,778
Ensembl chr21:123,449,106...123,460,807

RORA

RAR related orphan receptor A

involved_in

(PMID:18658046)
(PMID:19965867)

PMID:18658046 PMID:19965867

NCBI chr26:22,263,889...23,002,224
Ensembl chr26:22,812,445...22,993,021

RORC

RAR related orphan receptor C

involved_in

(PMID:19965867)

PMID:19965867

NCBI chr20:11,854,911...11,880,221
Ensembl chr20:11,855,005...11,879,717

cellular response to testosterone stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

acetoacetyl-CoA synthetase

NCBI chr11:120,422,138...120,502,200
Ensembl chr11:120,422,232...120,502,271

androgen receptor

involved_in

PMID:10428808 PMID:18761815

(MGI:5882884|PMID:18761815)
(PMID:10428808)

CAFA
ARUK-UCL

MGI:5882884

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

BRCA1 associated RING domain 1

NCBI chr10:100,539,827...100,627,718
Ensembl chr10:100,539,527...100,627,675

cyclin D2

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

insulin like growth factor 1 receptor

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

LOC103231899

ETS transcription factor ELK1

NCBI chr X:44,812,681...44,827,657

mitofusin 2

NCBI chr20:119,787,700...119,818,455
Ensembl chr20:119,787,370...119,816,693

MSN

moesin

involved_in

(PMID:24065547)

PMID:24065547

NCBI chr X:55,660,262...55,734,605
Ensembl chr X:55,660,234...55,735,191

MYC proto-oncogene, bHLH transcription factor

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

NCF1

neutrophil cytosolic factor 1

NCBI chr28:8,334,172...8,349,828
Ensembl chr28:8,332,772...8,349,804

nucleophosmin 1

NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925

RNF4

ring finger protein 4

NCBI chr27:46,245,786...46,290,671

ROCK2

Rho associated coiled-coil containing protein kinase 2

involved_in

GO_REF:0000107

NCBI chr14:96,275,889...96,443,048
Ensembl chr14:96,276,023...96,432,790

RWDD1

RWD domain containing 1

involved_in

(MGI:5882884|PMID:18761815)

PMID:18761815

MGI:5882884

NCBI chr13:57,215,415...57,238,455
Ensembl chr13:57,215,152...57,238,570

secreted phosphoprotein 1

involved_in

(PMID:26482249)

PMID:26482249

NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407

steroid 5 alpha-reductase 1

5alpha-dihydrotestosterone

PMID:15004407

RGD:4891941

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

cellular response to tetrahydrofolate

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SHMT1

serine hydroxymethyltransferase 1

involved_in

(PMID:24698160)

PMID:24698160

NCBI chr16:17,371,704...17,408,499

SHMT1

serine hydroxymethyltransferase 1

involved_in

GO_REF:0000107

Ensembl chr16:17,373,039...17,408,663

cellular response to thyroxine stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GCLC

glutamate-cysteine ligase catalytic subunit

NCBI chr17:19,012,994...19,060,617
Ensembl chr17:19,013,026...19,060,659

GCLM

glutamate-cysteine ligase modifier subunit

NCBI chr20:39,339,948...39,359,980
Ensembl chr20:39,339,908...39,359,430

L1CAM

L1 cell adhesion molecule

NCBI chr X:128,285,128...128,309,173
Ensembl chr X:128,285,130...128,299,570

cellular response to trichostatin A

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTR2

actin related protein 2

NCBI chr14:41,740,432...41,780,045
Ensembl chr14:41,739,968...41,779,964

ACTR3

actin related protein 3

NCBI chr10:16,296,350...16,369,561
Ensembl chr10:16,297,502...16,369,220

E1A binding protein p300

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

EZH2

enhancer of zeste 2 polycomb repressive complex 2 subunit

involved_in
acts_upstream_of_or_within

(PMID:24137001)

PMID:24137001

GO_REF:0000107

NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573

histone deacetylase 2

acts_upstream_of_or_within

(PMID:24137001)

PMID:24137001

NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742

HDAC8

histone deacetylase 8

NCBI chr X:62,154,374...62,393,149
Ensembl chr X:62,154,365...62,393,196

MEF2C

myocyte enhancer factor 2C

involved_in

(MGI:4440396|PMID:20181743)

PMID:20181743

MGI:4440396

NCBI chr 4:82,702,378...82,887,491
Ensembl chr 4:82,706,738...82,788,152

cellular response to vitamin B1

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MDM2 proto-oncogene

NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890

cellular response to vitamin D

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADAMTS1

ADAM metallopeptidase with thrombospondin type 1 motif 1

NCBI chr 2:65,376,288...65,385,398
Ensembl chr 2:65,376,310...65,385,918

ATP2B1

ATPase plasma membrane Ca2+ transporting 1

NCBI chr11:84,985,957...85,053,923
Ensembl chr11:84,989,169...85,103,957

bone gamma-carboxyglutamate protein

PMID:3257212 PMID:6607920

RGD:2316174 RGD:6483560

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

CASR

calcium sensing receptor

1,25-dihydroxycholecalciferol (calcitriol)

PMID:21940515

RGD:7205697

NCBI chr22:58,579,640...58,612,142
Ensembl chr22:58,578,396...58,604,756

CYP24A1

cytochrome P450 family 24 subfamily A member 1

NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884

FES

FES proto-oncogene, tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr29:8,967,542...8,979,475
Ensembl chr29:8,965,997...8,979,361

FGF23

fibroblast growth factor 23

NCBI chr11:4,398,318...4,408,415
Ensembl chr11:4,398,675...4,407,209

FZD1

frizzled class receptor 1

NCBI chr21:57,695,000...57,702,666
Ensembl chr21:57,699,468...57,701,417

FZD2

frizzled class receptor 2

NCBI chr16:61,837,202...61,839,126
Ensembl chr16:61,837,304...61,839,013

GDAP1

ganglioside induced differentiation associated protein 1

NCBI chr 8:69,948,800...69,965,168
Ensembl chr 8:69,949,052...69,966,421

interleukin 15

NCBI chr 7:88,548,773...88,644,977
Ensembl chr 7:88,548,671...88,645,488

ITGB1

integrin subunit beta 1

calcitriol

NCBI chr 9:32,201,030...32,258,247
Ensembl chr 9:32,202,204...32,258,154

KDM6A

lysine demethylase 6A

NCBI chr X:42,053,272...42,291,013
Ensembl chr X:42,053,336...42,290,526

LTBP1

latent transforming growth factor beta binding protein 1

NCBI chr14:74,063,258...74,441,042
Ensembl chr14:74,064,087...74,548,825

MMP1

matrix metallopeptidase 1

NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767

nitric oxide synthase 2

NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257

PDIA3

protein disulfide isomerase family A member 3

NCBI chr26:39,273,982...39,300,170
Ensembl chr26:39,272,997...39,349,966

proenkephalin

NCBI chr 8:52,458,113...52,463,933
Ensembl chr 8:52,457,904...52,463,859

PHEX

phosphate regulating endopeptidase X-linked

NCBI chr X:20,507,619...20,733,367
Ensembl chr X:20,522,498...20,734,599

pleiotrophin

NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215

secreted frizzled related protein 1

involved_in

GO_REF:0000107

NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984

SULT2A1

sulfotransferase family 2A member 1

NCBI chr 6:41,160,707...41,175,382
Ensembl chr 6:41,159,978...41,175,300

tenascin C

NCBI chr12:24,457,616...24,556,194
Ensembl chr12:24,457,738...24,556,451

TREM1

triggering receptor expressed on myeloid cells 1

NCBI chr17:30,873,647...30,885,292
Ensembl chr17:30,873,666...30,886,967

vitamin D receptor

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

cellular response to vitamin E

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

collagen type I alpha 1 chain

NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930

COL2A1

collagen type II alpha 1 chain

NCBI chr11:44,196,213...44,227,718
Ensembl chr11:44,196,094...44,227,468

PAWR

pro-apoptotic WT1 regulator

NCBI chr11:75,132,547...75,219,633
Ensembl chr11:75,133,186...75,219,072

peroxisome proliferator activated receptor gamma

NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418

cellular response to wortmannin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDC5L

cell division cycle 5 like

NCBI chr17:27,727,185...27,785,233
Ensembl chr17:27,722,819...27,785,268

creatine kinase B

NCBI chr24:81,462,164...81,463,873

estrogen receptor 1

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

hypoxia inducible factor 1 subunit alpha

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

progesterone receptor

NCBI chr 1:92,420,970...92,519,128
Ensembl chr 1:92,430,453...92,517,296

SP1

Sp1 transcription factor

NCBI chr11:49,484,459...49,516,941
Ensembl chr11:49,484,518...49,512,541

vascular endothelial growth factor A

NCBI chr17:28,377,959...28,394,508

dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY6

adenylate cyclase 6

involved_in

GO_REF:0000107

NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501

ARPP19

cAMP regulated phosphoprotein 19

NCBI chr26:30,825,846...30,844,005
Ensembl chr26:30,826,359...30,843,251

CALY

calcyon neuron specific vesicular protein

involved_in

GO_REF:0000002

NCBI chr26:53,170,933...53,182,147
Ensembl chr26:53,170,193...53,182,136

dopamine receptor D1

involved_in
acts_upstream_of_or_within

PMID:11089973 PMID:12097513 PMID:16908842

(PMID:11089973)
(PMID:16908842)
(PMID:12097513)

Ensembl
TreeGrafter
MGI

GO_REF:0000107 GO_REF:0000118

NCBI chr23:77,587,340...77,591,434

dopamine receptor D2

acts_upstream_of
involved_in

(PMID:12097513)

PMID:12097513 PMID:12121979

GO_REF:0000107 RGD:1581445

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

acts_upstream_of

(PMID:15016423)
(PMID:12097513)

PMID:12097513 PMID:15016423

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

dopamine receptor D4

involved_in

PMID:12711714

GO_REF:0000107 RGD:1358607

NCBI chr 1:454,018...459,582

dopamine receptor D5

involved_in

PMID:1831904

GO_REF:0000118 RGD:728422

NCBI chr27:40,267,681...40,270,061
Ensembl chr27:40,268,235...40,269,671

GNAI1

G protein subunit alpha i1

involved_in

GO_REF:0000107

NCBI chr21:68,687,809...68,770,415
Ensembl chr21:68,687,307...68,770,360

GNAI3

G protein subunit alpha i3

involved_in

GO_REF:0000107

NCBI chr20:23,950,819...24,000,069
Ensembl chr20:23,954,384...23,999,072

GNAO1

G protein subunit alpha o1

involved_in
acts_upstream_of_or_within

(PMID:11248120)

PMID:11248120

GO_REF:0000118

NCBI chr 5:42,105,295...42,272,573
Ensembl chr 5:42,105,334...42,273,059

GNB5

G protein subunit beta 5

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr26:31,209,843...31,265,440
Ensembl chr26:31,209,896...31,266,873

HTR1A

5-hydroxytryptamine receptor 1A

involved_in

GO_REF:0000118

NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212

HTR1B

5-hydroxytryptamine receptor 1B

involved_in

GO_REF:0000118

NCBI chr13:2,143,646...2,145,943
Ensembl chr13:2,144,313...2,145,485

HTR1D

5-hydroxytryptamine receptor 1D

involved_in

GO_REF:0000118

NCBI chr20:109,482,357...109,485,176
Ensembl chr20:109,482,863...109,483,996

HTT

huntingtin

acts_upstream_of_or_within

(PMID:17715336)

PMID:17715336

NCBI chr27:45,493,467...45,657,690
Ensembl chr27:45,497,352...45,657,621

KLF16

KLF transcription factor 16

involved_in
acts_upstream_of_or_within

(PMID:11390978)

PMID:11390978

GO_REF:0000107

NCBI chr 6:1,657,265...1,668,431
Ensembl chr 6:1,659,316...1,668,327

NCSTN

nicastrin

involved_in
acts_upstream_of_or_within

(PMID:27008863)

PMID:27008863

GO_REF:0000107

NCBI chr20:3,590,044...3,606,205
Ensembl chr20:3,590,725...3,606,066

NSG1

neuronal vesicle trafficking associated 1

involved_in

GO_REF:0000002

NCBI chr27:40,544,037...40,576,479
Ensembl chr27:40,544,701...40,579,108

NSG2

neuronal vesicle trafficking associated 2

involved_in

GO_REF:0000002

NCBI chr23:76,192,395...76,254,725
Ensembl chr23:76,192,456...76,255,057

RGS9

regulator of G protein signaling 9

NCBI chr16:56,199,051...56,291,002
Ensembl chr16:56,199,343...56,288,290

solute carrier family 1 member 1

involved_in

(PMID:28507136), (PMID:29229708)

PMID:28507136 PMID:29229708

NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369

glucocorticoid mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nuclear receptor subfamily 3 group C member 1

involved_in

GO_REF:0000002

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

histamine secretion mediated by IgE immunoglobulin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB44

RAB44, member RAS oncogene family

acts_upstream_of_or_within

(PMID:32238914)

PMID:32238914

NCBI chr17:35,399,866...35,435,599

immune response involved in response to exogenous dsRNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HCFC2

host cell factor C2

acts_upstream_of_or_within

(PMID:28970238)

PMID:28970238

NCBI chr11:99,264,638...99,303,923
Ensembl chr11:99,264,674...99,303,732

intracellular corticosteroid receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nuclear receptor subfamily 3 group C member 1

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

NR3C2

nuclear receptor subfamily 3 group C member 2

NCBI chr 7:94,574,010...94,935,348

intracellular estrogen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

androgen receptor

involved_in
acts_upstream_of

PMID:10428808 PMID:14676301

(PMID:10428808)
(PMID:14676301)

ARUK-UCL
MGI

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

ARID1A

AT-rich interaction domain 1A

involved_in

GO_REF:0000107

NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672

coactivator associated arginine methyltransferase 1

acts_upstream_of_or_within

(PMID:12756295)

PMID:12756295

NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682

CYP7B1

cytochrome P450 family 7 subfamily B member 1

involved_in
acts_upstream_of

(PMID:12370428)

GO_REF:0000107

NCBI chr 8:60,496,607...60,691,457
Ensembl chr 8:60,496,733...60,524,238

DDX17

DEAD-box helicase 17

involved_in

GO_REF:0000107

NCBI chr19:21,145,576...21,167,091
Ensembl chr19:21,145,417...21,167,543

DDX5

DEAD-box helicase 5

involved_in

GO_REF:0000107

NCBI chr16:56,766,669...56,773,767
Ensembl chr16:56,767,186...56,773,464

DEFA1

defensin alpha 1

involved_in

(PMID:21861873)

PMID:21861873

NCBI chr 8:6,773,316...6,778,688

estrogen receptor 1

involved_in

GO_REF:0000118

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

estrogen receptor 2

involved_in
acts_upstream_of_or_within

(PMID:12370428)

InterPro
MGI
TreeGrafter

GO_REF:0000002 GO_REF:0000118

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

G protein-coupled estrogen receptor 1

NCBI chr28:20,491,874...20,497,966
Ensembl chr28:20,492,188...20,493,315

LOC103232243

prohibitin-2-like

involved_in

GO_REF:0000107

NCBI chr X:67,716,566...67,718,426

PADI2

peptidyl arginine deiminase 2

involved_in

GO_REF:0000107

NCBI chr20:115,465,098...115,520,772
Ensembl chr20:115,465,338...115,520,828

PHB2

prohibitin 2

acts_upstream_of

(PMID:17065319)

PMID:17065319

NCBI chr11:6,998,517...7,004,437

POU4F2

POU class 4 homeobox 2

involved_in

GO_REF:0000107

NCBI chr 7:93,150,105...93,160,977
Ensembl chr 7:93,150,186...93,151,857

PPARGC1B

PPARG coactivator 1 beta

involved_in

GO_REF:0000107

NCBI chr23:52,337,802...52,462,553
Ensembl chr23:52,428,052...52,455,089

RBFOX2

RNA binding fox-1 homolog 2

involved_in

(PMID:11875103)

PMID:11875103

NCBI chr19:18,507,184...18,801,535

SAFB

scaffold attachment factor B

involved_in
acts_upstream_of_or_within

(PMID:15798188)

PMID:15798188

GO_REF:0000118

NCBI chr 6:5,281,171...5,326,049
Ensembl chr 6:5,281,232...5,328,511

TAF7

TATA-box binding protein associated factor 7

involved_in
acts_upstream_of_or_within

(PMID:10438527)

PMID:10438527

GO_REF:0000107

NCBI chr23:43,938,202...43,940,486
Ensembl chr23:43,938,714...43,939,763

TRIP4

thyroid hormone receptor interactor 4

involved_in

GO_REF:0000107

NCBI chr26:19,065,934...19,133,489
Ensembl chr26:19,065,887...19,133,448

intracellular glucocorticoid receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ARID1A

AT-rich interaction domain 1A

involved_in

GO_REF:0000107

NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672

NEDD4

NEDD4 E3 ubiquitin protein ligase

involved_in

GO_REF:0000107

NCBI chr26:27,487,652...27,655,742
Ensembl chr26:27,487,796...27,655,992

nuclear receptor subfamily 3 group C member 1

involved_in
acts_upstream_of_or_within

PMID:7628695 PMID:10224232 PMID:15199138

(PMID:10224232)
(PMID:7628695)
(PMID:15199138)

InterPro
MGI
Ensembl

GO_REF:0000002 GO_REF:0000107

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

PTGES3

prostaglandin E synthase 3

acts_upstream_of_or_within

(PMID:17438133)

PMID:17438133

NCBI chr11:52,609,460...52,634,490

YWHAH

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta

involved_in

GO_REF:0000107

NCBI chr19:14,825,963...14,839,668
Ensembl chr19:14,826,135...14,840,325

intracellular mineralocorticoid receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Janus kinase 2

NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710

intracellular steroid hormone receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

androgen receptor

involved_in

GO_REF:0000118

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

CALCOCO1

calcium binding and coiled-coil domain 1

involved_in

GO_REF:0000107

NCBI chr11:49,816,546...49,833,655
Ensembl chr11:49,814,007...49,833,632

coactivator associated arginine methyltransferase 1

involved_in

(MGI:3530629|PMID:14690606)

HGNC-UCL

PMID:14690606

MGI:3530629

NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682

estrogen receptor 1

involved_in

PMID:15705806 PMID:17928626

PMID:15705806

RGD
UniProt

RGD:5128669 RGD:8553914

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

estrogen receptor 2

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

ESRRA

estrogen related receptor alpha

involved_in

GO_REF:0000118

NCBI chr 1:9,918,741...9,929,481
Ensembl chr 1:9,917,436...9,929,450

ESRRB

estrogen related receptor beta

involved_in

GO_REF:0000118

NCBI chr24:53,630,998...53,762,098

ESRRG

estrogen related receptor gamma

involved_in

GO_REF:0000118

NCBI chr25:12,495,234...13,090,739
Ensembl chr25:12,866,321...13,090,733

G protein-coupled estrogen receptor 1

involved_in

RGD
TreeGrafter
Ensembl

PMID:20445128

GO_REF:0000107 GO_REF:0000118 RGD:4892084

NCBI chr28:20,491,874...20,497,966
Ensembl chr28:20,492,188...20,493,315

mediator complex subunit 1

involved_in

GO_REF:0000107

NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896

nuclear receptor subfamily 3 group C member 1

involved_in

GO_REF:0000118

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

progesterone receptor

involved_in

GO_REF:0000118

NCBI chr 1:92,420,970...92,519,128
Ensembl chr 1:92,430,453...92,517,296

mRNA export from nucleus in response to heat stress

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TPR

translocated promoter region, nuclear basket protein

involved_in

GO_REF:0000107

NCBI chr25:43,056,605...43,120,570
Ensembl chr25:43,056,886...43,123,474

negative regulation of androgen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DAB2

DAB adaptor protein 2

involved_in

GO_REF:0000107

NCBI chr 4:38,171,320...38,224,275
Ensembl chr 4:38,173,026...38,224,231

estrogen receptor 2

acts_upstream_of_or_within

(PMID:12370428)

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

FOXH1

forkhead box H1

involved_in

GO_REF:0000107

NCBI chr 8:138,685,137...138,688,451
Ensembl chr 8:138,685,626...138,687,144

FOXP1

forkhead box P1

involved_in

GO_REF:0000107

NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502

HDAC1

histone deacetylase 1

involved_in

(PMID:15919722)

PMID:15919722

NCBI chr20:100,529,782...100,575,953
Ensembl chr20:100,530,369...100,558,556

HEYL

hes related family bHLH transcription factor with YRPW motif like

involved_in

GO_REF:0000107

NCBI chr20:93,230,189...93,246,549

insulin like growth factor 1

acts_upstream_of_or_within

(PMID:18827067)

PMID:18827067

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

NCOR1

nuclear receptor corepressor 1

involved_in

GO_REF:0000107

NCBI chr16:15,442,315...15,629,411
Ensembl chr16:15,462,640...15,628,512

NCOR2

nuclear receptor corepressor 2

involved_in

GO_REF:0000107

NCBI chr11:119,675,363...119,917,059
Ensembl chr11:119,676,345...119,917,000

NODAL

nodal growth differentiation factor

involved_in

(PMID:21656830)

PMID:21656830

NCBI chr 9:60,852,567...60,863,225
Ensembl chr 9:60,853,763...60,862,839

PHB1

prohibitin 1

involved_in

(PMID:16964284)
(PMID:18487222)

PMID:16964284 PMID:18487222

NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754

protein inhibitor of activated STAT 2

involved_in

(PMID:11477070)

PMID:11477070

NCBI chr18:33,967,894...34,075,824
Ensembl chr18:33,967,999...34,067,910

secreted frizzled related protein 1

involved_in

GO_REF:0000107

NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984

sirtuin 1

involved_in

GO_REF:0000107

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

involved_in

(PMID:18487222)

PMID:18487222

NCBI chr 6:9,943,162...10,044,476

TCF21

transcription factor 21

involved_in

GO_REF:0000107

NCBI chr13:39,607,179...39,610,336
Ensembl chr13:39,607,182...39,610,388

ZBTB7A

zinc finger and BTB domain containing 7A

involved_in

GO_REF:0000107

NCBI chr 6:3,802,171...3,824,552
Ensembl chr 6:3,801,046...3,812,884

negative regulation of cellular response to testosterone stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sirtuin 1

involved_in

GO_REF:0000107

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

negative regulation of dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

dopamine receptor D2

involved_in
acts_upstream_of_or_within

(PMID:12097513)

PMID:12097513

GO_REF:0000107

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

acts_upstream_of_or_within

(PMID:12097513)

PMID:12097513

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

PALM

paralemmin

involved_in

GO_REF:0000107

NCBI chr 6:461,030...503,688
Ensembl chr 6:474,474...504,230

RGS4

regulator of G protein signaling 4

NCBI chr25:65,729,344...65,735,278
Ensembl chr25:65,726,394...65,735,381

negative regulation of glucocorticoid mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CREBRF

CREB3 regulatory factor

involved_in
acts_upstream_of_or_within

(MGI:5466657|PMID:23071095)
(PMID:23071095)

CACAO
MGI

PMID:23071095

MGI:5466657

NCBI chr23:75,219,847...75,302,641
Ensembl chr23:75,219,873...75,297,114

negative regulation of glucocorticoid receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMAL1

basic helix-loop-helix ARNT like 1

involved_in

(MGI:5567887|PMID:24378737)

PMID:24378737

MGI:5567887

NCBI chr 1:51,430,670...51,540,344
Ensembl chr 1:51,431,180...51,462,674

CLOCK

clock circadian regulator

involved_in

GO_REF:0000107

NCBI chr 7:13,015,198...13,134,741
Ensembl chr 7:13,051,454...13,127,240

CRY1

cryptochrome circadian regulator 1

involved_in

GO_REF:0000107

NCBI chr11:102,200,822...102,306,165
Ensembl chr11:102,204,224...102,306,182

CRY2

cryptochrome circadian regulator 2

involved_in

GO_REF:0000107

NCBI chr 1:19,459,734...19,498,807
Ensembl chr 1:19,472,231...19,498,790

PER1

period circadian regulator 1

involved_in

GO_REF:0000107

NCBI chr16:7,520,122...7,536,176
Ensembl chr16:7,520,006...7,531,940

PHB1

prohibitin 1

involved_in

(PMID:16964284)

PMID:16964284

NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754

negative regulation of intracellular estrogen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BRCA1 DNA repair associated

involved_in

(PMID:17505062)

CACAO

PMID:17505062

NCBI chr16:63,162,827...63,243,928

CNOT1

CCR4-NOT transcription complex subunit 1

involved_in

(PMID:16778766)

PMID:16778766

NCBI chr 5:44,460,025...44,567,843
Ensembl chr 5:44,455,311...44,567,815

CNOT2

CCR4-NOT transcription complex subunit 2

involved_in

GO_REF:0000107

NCBI chr11:65,823,294...65,932,588
Ensembl chr11:65,861,353...65,934,042

CNOT9

CCR4-NOT transcription complex subunit 9

involved_in

GO_REF:0000107

NCBI chr10:104,473,215...104,502,321
Ensembl chr10:104,473,216...104,503,007

CYP7B1

cytochrome P450 family 7 subfamily B member 1

involved_in
acts_upstream_of_or_within

(PMID:12370428)

GO_REF:0000107

NCBI chr 8:60,496,607...60,691,457
Ensembl chr 8:60,496,733...60,524,238

FOXH1

forkhead box H1

involved_in

GO_REF:0000107

NCBI chr 8:138,685,137...138,688,451
Ensembl chr 8:138,685,626...138,687,144

ISL1

ISL LIM homeobox 1

involved_in

PMID:11043578

NCBI chr 4:47,665,861...47,678,631
Ensembl chr 4:47,666,536...47,677,552

KANK2

KN motif and ankyrin repeat domains 2

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 6:10,095,319...10,131,985
Ensembl chr 6:10,095,246...10,131,946

LBH

LBH regulator of WNT signaling pathway

involved_in

(MGI:5634223|PMID:25655704)

PMID:25655704

MGI:5634223

NCBI chr14:77,278,080...77,306,721
Ensembl chr14:77,280,510...77,306,518

LOC103232243

prohibitin-2-like

involved_in

GO_REF:0000107

NCBI chr X:67,716,566...67,718,426

PHB2

prohibitin 2

acts_upstream_of_or_within

(PMID:17785450)
(PMID:17065319)

PMID:17065319 PMID:17785450

NCBI chr11:6,998,517...7,004,437

TP63

tumor protein p63

involved_in

(MGI:5634223|PMID:25655704)

PMID:25655704

MGI:5634223

NCBI chr15:83,861,489...84,126,675

TP63

tumor protein p63

involved_in

GO_REF:0000107

Ensembl chr15:84,093,957...84,123,905

VPS11

VPS11 core subunit of CORVET and HOPS complexes

involved_in

(PMID:31015428)

FlyBase

PMID:31015428

NCBI chr 1:110,440,681...110,455,092
Ensembl chr 1:110,439,933...110,455,844

VPS18

VPS18 core subunit of CORVET and HOPS complexes

involved_in

(PMID:31015428)

FlyBase

PMID:31015428

NCBI chr26:42,091,348...42,100,264
Ensembl chr26:42,088,938...42,100,243

ZNF366

zinc finger protein 366

involved_in

GO_REF:0000107

NCBI chr 4:66,779,113...66,844,839
Ensembl chr 4:66,776,547...66,843,905

negative regulation of intracellular steroid hormone receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CALR

calreticulin

involved_in

(PMID:8107809)

PMID:8107809

NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792

HMGA2

high mobility group AT-hook 2

NCBI chr11:61,509,114...61,655,633

NR0B1

nuclear receptor subfamily 0 group B member 1

involved_in

(PMID:11875111)

PMID:11875111

NCBI chr X:28,707,698...28,713,158
Ensembl chr X:28,707,699...28,712,708

RHOA

ras homolog family member A

involved_in
acts_upstream_of_or_within

(PMID:16254014)

PMID:16254014

GO_REF:0000107

NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704

negative regulation of vitamin D receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KANK2

KN motif and ankyrin repeat domains 2

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 6:10,095,319...10,131,985
Ensembl chr 6:10,095,246...10,131,946

SNAI2

snail family transcriptional repressor 2

involved_in

(PMID:19502595)

PMID:19502595

NCBI chr 8:45,043,381...45,047,054
Ensembl chr 8:45,043,393...45,046,978

phospholipase C-activating dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

dopamine receptor D1

involved_in
acts_upstream_of_or_within

(PMID:15016423)
(PMID:17194762)

PMID:15016423 PMID:17194762

GO_REF:0000107

NCBI chr23:77,587,340...77,591,434

dopamine receptor D2

acts_upstream_of_or_within
involved_in

PMID:15016423 PMID:17194762

(PMID:17194762)
(PMID:15016423)

MGI
TreeGrafter
Ensembl

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

involved_in

GO_REF:0000118

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

dopamine receptor D4

involved_in

GO_REF:0000118

NCBI chr 1:454,018...459,582

GNA11

G protein subunit alpha 11

involved_in
acts_upstream_of_or_within

(PMID:17194762)

PMID:17194762

GO_REF:0000118

NCBI chr 6:2,858,880...2,887,694
Ensembl chr 6:2,858,937...2,887,704

GNA14

G protein subunit alpha 14

involved_in

GO_REF:0000118

NCBI chr12:88,386,597...88,606,787
Ensembl chr12:88,385,377...88,605,845

GNA15

G protein subunit alpha 15

involved_in

GO_REF:0000118

NCBI chr 6:2,901,502...2,930,567
Ensembl chr 6:2,901,762...2,932,138

GNAQ

G protein subunit alpha q

involved_in
acts_upstream_of_or_within

(PMID:17194762)

PMID:17194762

GO_REF:0000118

NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154

NHERF1

NHERF family PDZ scaffold protein 1

involved_in
acts_upstream_of_or_within

(PMID:20200151)

PMID:20200151

GO_REF:0000107

NCBI chr16:46,889,454...46,910,776
Ensembl chr16:46,888,942...46,910,842

positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PRMT5

protein arginine methyltransferase 5

involved_in

GO_REF:0000107

NCBI chr29:23,288,458...23,297,746
Ensembl chr29:23,288,835...23,297,518

positive regulation of dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAV2

caveolin 2

involved_in

(PMID:15569306)

PMID:15569306

NCBI chr21:85,197,452...85,206,521
Ensembl chr21:85,197,537...85,206,588

dopamine receptor D3

acts_upstream_of_or_within

(PMID:15016423)

PMID:15016423

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

leucine rich repeat kinase 2

involved_in

(PMID:20659558)

PMID:20659558

NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216

VPS35

VPS35 retromer complex component

involved_in

GO_REF:0000107

NCBI chr 5:32,509,037...32,539,371
Ensembl chr 5:32,508,580...32,539,343

positive regulation of glucocorticoid receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

brain derived neurotrophic factor

acts_upstream_of_or_within

PMID:23878391

NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336

LMO3

LIM domain only 3

involved_in

(PMID:23823477)

PMID:23823477

NCBI chr11:16,454,240...16,516,403

NCOA2

nuclear receptor coactivator 2

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

nuclear receptor subfamily 3 group C member 1

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

NTRK2

neurotrophic receptor tyrosine kinase 2

acts_upstream_of_or_within

PMID:23878391

NCBI chr12:95,477,612...95,836,734
Ensembl chr12:95,479,447...95,620,364

PPP5C

protein phosphatase 5 catalytic subunit

NCBI chr 6:39,726,627...39,767,467
Ensembl chr 6:39,726,623...39,767,464

positive regulation of intracellular estrogen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

androgen receptor

acts_upstream_of_or_within

(PMID:14676301)

PMID:14676301

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

FOXA1

forkhead box A1

involved_in

GO_REF:0000107

NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094

FSHR

follicle stimulating hormone receptor

involved_in
acts_upstream_of_or_within

(PMID:11089565)

PMID:11089565

GO_REF:0000107

NCBI chr14:58,013,405...58,211,528
Ensembl chr14:58,013,742...58,212,755

KMT2D

lysine methyltransferase 2D

involved_in

GO_REF:0000107

NCBI chr11:45,260,873...45,303,898
Ensembl chr11:45,263,408...45,302,423

LOC103245755

WW domain-binding protein 2-like

involved_in

GO_REF:0000107

NCBI chr26:40,120,432...40,122,225

mediator complex subunit 1

involved_in
acts_upstream_of_or_within

(PMID:20351249)

PMID:20351249

GO_REF:0000107

NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896

NCOA3

nuclear receptor coactivator 3

NCBI chr 2:16,270,218...16,423,381
Ensembl chr 2:16,273,717...16,423,318

PAGR1

PAXIP1 associated glutamate rich protein 1

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 5:26,833,333...26,837,655
Ensembl chr 5:26,833,675...26,837,640

PAK1

p21 (RAC1) activated kinase 1

involved_in

GO_REF:0000107

NCBI chr 1:68,530,037...68,679,413
Ensembl chr 1:68,529,571...68,617,092

PARP1

poly(ADP-ribose) polymerase 1

NCBI chr25:3,350,798...3,405,040

SKP2

S-phase kinase associated protein 2

involved_in
acts_upstream_of_or_within

(PMID:17785450)

PMID:17785450

GO_REF:0000107

NCBI chr 4:35,009,114...35,040,518
Ensembl chr 4:35,009,076...35,042,632

SRARP

steroid receptor associated and regulated protein

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr20:116,293,054...116,296,291
Ensembl chr20:116,293,000...116,295,874

WBP2

WW domain binding protein 2

involved_in

GO_REF:0000107

NCBI chr16:45,821,875...45,836,558
Ensembl chr16:45,821,967...45,835,530

positive regulation of intracellular steroid hormone receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NCOA3

nuclear receptor coactivator 3

glucocorticoid receptor signaling in astrocytes

PMID:16179382

RGD:1642052

NCBI chr 2:16,270,218...16,423,381
Ensembl chr 2:16,273,717...16,423,318

UBE2I

ubiquitin conjugating enzyme E2 I

glucocorticoid receptor, independent of sumoylation activity or presence of a GME

PMID:11812797

RGD:2301354

NCBI chr 5:1,203,513...1,216,662
Ensembl chr 5:1,200,018...1,216,741

positive regulation of vitamin D receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYP27B1

cytochrome P450 family 27 subfamily B member 1

involved_in

GO_REF:0000107

NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443

MN1

MN1 proto-oncogene, transcriptional regulator

involved_in

(PMID:15890672)

PMID:15890672

NCBI chr19:10,652,940...10,706,989
Ensembl chr19:10,652,939...10,706,762

retinoid X receptor alpha

involved_in

(PMID:20171278)

ComplexPortal

PMID:20171278

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

SNW1

SNW domain containing 1

involved_in

(PMID:11514567), (PMID:9632709)

PMID:9632709 PMID:11514567

NCBI chr24:54,976,597...55,020,051
Ensembl chr24:54,977,083...55,019,988

VDR

vitamin D receptor

involved_in

GO_REF:0000107

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

progesterone receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ERBB receptor feedback inhibitor 1

acts_upstream_of_or_within

(PMID:25976672)

PMID:25976672

NCBI chr20:123,738,971...123,753,575
Ensembl chr20:123,738,973...123,755,809

KLF9

KLF transcription factor 9

acts_upstream_of_or_within

(PMID:15117941)

PMID:15117941

NCBI chr12:81,451,210...81,481,384
Ensembl chr12:81,454,394...81,480,094

LOC103245755

WW domain-binding protein 2-like

involved_in

GO_REF:0000107

NCBI chr26:40,120,432...40,122,225

mitogen-activated protein kinase 1

involved_in

GO_REF:0000107

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

NEDD4

NEDD4 E3 ubiquitin protein ligase

involved_in

GO_REF:0000107

NCBI chr26:27,487,652...27,655,742
Ensembl chr26:27,487,796...27,655,992

progesterone receptor

acts_upstream_of_or_within

(PMID:16176985)

PMID:16176985

NCBI chr 1:92,420,970...92,519,128
Ensembl chr 1:92,430,453...92,517,296

PHB1

prohibitin 1

involved_in

(PMID:16964284)

PMID:16964284

NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in

GO_REF:0000118

NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776

TRERF1

transcriptional regulating factor 1

involved_in

(PMID:17015480)

PMID:17015480

NCBI chr17:29,700,505...29,927,247
Ensembl chr17:29,883,231...29,927,388

ubiquitin protein ligase E3A

involved_in

(PMID:16772533)

PMID:16772533

NCBI chr26:56,638,936...56,738,555
Ensembl chr26:56,666,162...56,736,737

UBR5

ubiquitin protein ligase E3 component n-recognin 5

involved_in

GO_REF:0000107

NCBI chr 8:97,104,325...97,257,317
Ensembl chr 8:97,103,220...97,257,440

WBP2

WW domain binding protein 2

involved_in

GO_REF:0000107

NCBI chr16:45,821,875...45,836,558
Ensembl chr16:45,821,967...45,835,530

ZDHHC7

zinc finger DHHC-type palmitoyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 5:70,379,228...70,419,885
Ensembl chr 5:70,379,179...70,401,139

regulation of androgen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DDX5

DEAD-box helicase 5

involved_in

GO_REF:0000107

NCBI chr16:56,766,669...56,773,767
Ensembl chr16:56,767,186...56,773,464

E1A binding protein p300

involved_in

GO_REF:0000107

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

PARK7

Parkinsonism associated deglycase

involved_in

GO_REF:0000107

NCBI chr20:123,776,084...123,808,031
Ensembl chr20:123,776,297...123,798,434

protein inhibitor of activated STAT 2

acts_upstream_of_or_within

PMID:9920921

NCBI chr18:33,967,894...34,075,824
Ensembl chr18:33,967,999...34,067,910

PRMT2

protein arginine methyltransferase 2

involved_in

(PMID:17587566)

PMID:17587566

NCBI chr 2:90,225,051...90,256,541
Ensembl chr 2:90,225,346...90,256,558

RNF14

ring finger protein 14

involved_in

GO_REF:0000107

NCBI chr23:44,602,152...44,623,711
Ensembl chr23:44,602,783...44,623,912

RNF6

ring finger protein 6

involved_in

(PMID:19345326)

PMID:19345326

NCBI chr 3:5,461,053...5,471,268
Ensembl chr 3:5,462,126...5,468,555

SAFB2

scaffold attachment factor B2

involved_in
acts_upstream_of_or_within

(PMID:26092125)

PMID:26092125

GO_REF:0000118

NCBI chr 6:5,244,072...5,281,053
Ensembl chr 6:5,244,000...5,280,932

TRIM68

tripartite motif containing 68

involved_in

(PMID:18451177)

PMID:18451177

NCBI chr 1:62,270,614...62,280,241

USP26

ubiquitin specific peptidase 26

involved_in

GO_REF:0000107

NCBI chr X:108,187,526...108,275,829
Ensembl chr X:108,187,858...108,190,605

regulation of cellular response to testosterone stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC39A9

solute carrier family 39 member 9

involved_in

(MGI:6791231|PMID:26208885)

PMID:26208885

MGI:6791231

NCBI chr24:46,642,307...46,708,349
Ensembl chr24:46,643,304...46,704,569

regulation of dopamine receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ALK

ALK receptor tyrosine kinase

acts_upstream_of_or_within

(PMID:17487225)

PMID:17487225

NCBI chr14:77,632,809...78,408,307

ALK

ALK receptor tyrosine kinase

involved_in

GO_REF:0000107

Ensembl chr14:78,200,889...78,406,094

DTNBP1

dystrobrevin binding protein 1

involved_in

PMID:17989303

NCBI chr17:56,500,523...56,650,925
Ensembl chr17:56,500,574...56,651,491

leucine rich repeat kinase 2

involved_in

(MGI:5553024|PMID:24464040)

ParkinsonsUK-UCL

PMID:24464040

MGI:5553024

NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216

RGS8

regulator of G protein signaling 8

involved_in

PMID:9394004

NCBI chr25:46,683,978...46,724,205
Ensembl chr25:46,683,783...46,726,543

regulation of eIF2 alpha phosphorylation by dsRNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NPM1

nucleophosmin 1

involved_in

GO_REF:0000107

NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925

regulation of glucocorticoid mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AKAP13

A-kinase anchoring protein 13

acts_upstream_of_or_within

(PMID:16469733)

PMID:16469733

NCBI chr29:4,009,921...4,364,226
Ensembl chr29:4,106,732...4,359,516

regulation of intracellular estrogen receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

coactivator associated arginine methyltransferase 1

involved_in

(MGI:4887320|PMID:19843527)

PMID:19843527

MGI:4887320

NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682

DDRGK1

DDRGK domain containing 1

involved_in

GO_REF:0000107

NCBI chr 2:33,846,591...33,879,770
Ensembl chr 2:33,860,439...33,880,101

DNAAF4

dynein axonemal assembly factor 4

involved_in

(PMID:19423554)

PMID:19423554

NCBI chr26:27,946,092...28,024,495

DNAAF4

dynein axonemal assembly factor 4

involved_in

GO_REF:0000107

Ensembl chr26:27,960,224...28,013,105

FSHR

follicle stimulating hormone receptor

involved_in
acts_upstream_of_or_within

(PMID:18063689), (PMID:18676690)

PMID:18063689 PMID:18676690

GO_REF:0000107

NCBI chr14:58,013,405...58,211,528
Ensembl chr14:58,013,742...58,212,755

LATS1

large tumor suppressor kinase 1

involved_in

GO_REF:0000107

NCBI chr13:21,901,153...21,966,227
Ensembl chr13:21,919,280...21,967,117

SRC proto-oncogene, non-receptor tyrosine kinase

involved_in
acts_upstream_of_or_within

(PMID:16007215)

PMID:16007215

GO_REF:0000107

NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776

UBA5

ubiquitin like modifier activating enzyme 5

involved_in

GO_REF:0000107

NCBI chr15:57,596,490...57,613,103
Ensembl chr15:57,592,728...57,612,928

UFL1

UFM1 specific ligase 1

involved_in

(PMID:25219498)

PMID:25219498

NCBI chr13:77,357,239...77,387,385
Ensembl chr13:77,357,141...77,387,367

UFM1

ubiquitin fold modifier 1

involved_in

(PMID:25219498)

PMID:25219498

NCBI chr 3:16,812,925...16,826,011
Ensembl chr 3:16,813,148...16,823,910

UFSP2

UFM1 specific peptidase 2

involved_in

(PMID:25219498)

PMID:25219498

NCBI chr 7:131,352,140...131,375,558
Ensembl chr 7:131,350,251...131,375,549

regulation of intracellular steroid hormone receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GHRHR

growth hormone releasing hormone receptor

acts_upstream_of_or_within

(PMID:10459853)

PMID:10459853

NCBI chr21:27,402,765...27,417,536
Ensembl chr21:27,404,886...27,417,521

regulation of vitamin D receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

mediator complex subunit 1

involved_in
acts_upstream_of_or_within

(PMID:16324150)

PMID:16324150

GO_REF:0000107

NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896

SNW1

SNW domain containing 1

involved_in

(PMID:14985122)

PMID:14985122

NCBI chr24:54,976,597...55,020,051
Ensembl chr24:54,977,083...55,019,988

TRIM24

tripartite motif containing 24

acts_upstream_of_or_within

(PMID:18287084)

PMID:18287084

NCBI chr21:107,166,180...107,291,897
Ensembl chr21:107,166,395...107,295,736

response to 11-deoxycorticosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HDAC8

histone deacetylase 8

NCBI chr X:62,154,374...62,393,149
Ensembl chr X:62,154,365...62,393,196

response to 2,3,7,8-tetrachlorodibenzodioxine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily G member 2 (JR blood group)

NCBI chr 7:36,458,110...36,599,753

cytochrome P450 family 1 subfamily A member 1

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

coagulation factor VII

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

secreted phosphoprotein 1

NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407

TIPARP

TCDD inducible poly(ADP-ribose) polymerase

NCBI chr15:34,041,208...34,073,428
Ensembl chr15:34,039,657...34,073,319

response to 3,3',5-triiodo-L-thyronine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP5F1B

ATP synthase F1 subunit beta

NCBI chr11:52,587,608...52,600,057
Ensembl chr11:52,587,143...52,600,756

ATP5MC1

ATP synthase membrane subunit c locus 1

NCBI chr16:69,307,094...69,312,257
Ensembl chr16:69,307,175...69,312,254

ATP5MC2

ATP synthase membrane subunit c locus 2

NCBI chr11:49,768,977...49,780,664
Ensembl chr11:49,768,783...49,780,081

TIMM44

translocase of inner mitochondrial membrane 44

NCBI chr 6:7,378,091...7,394,927
Ensembl chr 6:7,377,669...7,396,652

TNF

tumor necrosis factor

translocase of outer mitochondrial membrane 20

NCBI chr25:72,286,666...72,304,129

response to 3-methylcholanthrene

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

choline kinase alpha

NCBI chr 1:6,411,606...6,482,508

cytochrome P450 family 1 subfamily A member 1

PMID:10772642 PMID:19889059

RGD:2306641 RGD:401794453

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

cytochrome P450 family 1 subfamily B member 1

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

CYP2E1

cytochrome P450 family 2 subfamily E member 1

NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211

epoxide hydrolase 2

NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345

heme oxygenase 1

NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971

NPPA

natriuretic peptide A

NCBI chr20:119,942,412...119,946,211
Ensembl chr20:119,944,532...119,945,917

NPPB

natriuretic peptide B

NCBI chr20:119,930,931...119,933,391
Ensembl chr20:119,932,021...119,933,197

response to 4-nitroquinoline N-oxide

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

JunB proto-oncogene, AP-1 transcription factor subunit

NCBI chr 6:11,479,108...11,480,942
Ensembl chr 6:11,479,407...11,480,450

response to aldosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACVR1C

activin A receptor type 1C

NCBI chr10:42,935,085...43,030,581
Ensembl chr10:42,942,284...42,994,488

ASNS

asparagine synthetase (glutamine-hydrolyzing)

NCBI chr21:51,244,514...51,264,694
Ensembl chr21:51,247,742...51,265,241

BRCA1 associated RING domain 1

NCBI chr10:100,539,827...100,627,718
Ensembl chr10:100,539,527...100,627,675

CARD9

caspase recruitment domain family member 9

NCBI chr12:1,829,913...1,841,489
Ensembl chr12:1,832,989...1,837,914

cyclin dependent kinase inhibitor 1A

NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342

corticotropin releasing hormone

NCBI chr 8:62,052,155...62,056,424
Ensembl chr 8:62,052,592...62,053,182

CYBB

cytochrome b-245 heavy chain

Fc fragment of IgG receptor Ia

inhibin subunit beta A

NCBI chr21:16,936,054...16,951,430
Ensembl chr21:16,936,175...16,946,880

KCNH8

potassium voltage-gated channel subfamily H member 8

NCBI chr15:63,954,331...64,334,300

LCK

LCK proto-oncogene, Src family tyrosine kinase

NCBI chr20:100,582,718...100,618,041

LOC103233451

cytochrome b-245 light chain

NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750

PARP1

poly(ADP-ribose) polymerase 1

NCBI chr25:3,350,798...3,405,040

PHLDA1

pleckstrin homology like domain family A member 1

NCBI chr11:71,621,536...71,630,051

PTPRC

protein tyrosine phosphatase receptor type C

NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303

RPL27

ribosomal protein L27

NCBI chr16:63,287,493...63,292,054
Ensembl chr16:63,287,208...63,292,473

SH3RF1

SH3 domain containing ring finger 1

NCBI chr 7:115,330,171...115,504,443
Ensembl chr 7:115,332,460...115,504,411

SLC12A3

solute carrier family 12 member 3

involved_in

(PMID:19690383)

PMID:19690383

NCBI chr 5:42,808,773...42,877,714
Ensembl chr 5:42,811,597...42,862,002

STK39

serine/threonine kinase 39

involved_in

GO_REF:0000107

NCBI chr10:53,451,035...53,747,847
Ensembl chr10:53,450,891...53,682,993

TBX5

T-box transcription factor 5

NCBI chr11:109,638,694...109,696,619
Ensembl chr11:109,638,715...109,689,177

vitamin D receptor

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

response to amitrole

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

catalase

NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592

response to ATP

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCC9

ATP binding cassette subfamily C member 9

involved_in
acts_upstream_of_or_within

(PMID:30089727)

PMID:30089727

GO_REF:0000107

NCBI chr11:21,658,804...21,797,851
Ensembl chr11:21,658,794...21,797,263

AMPD1

adenosine monophosphate deaminase 1

NCBI chr20:18,973,547...18,996,082
Ensembl chr20:18,974,204...18,996,293

ASPH

aspartate beta-hydroxylase

involved_in

(PMID:21062895)

PMID:21062895

NCBI chr 8:57,378,019...57,599,812
Ensembl chr 8:57,375,894...57,565,259

CASP1

caspase 1

acts_upstream_of_or_within

(PMID:18490713)

PMID:18490713

NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849

DGKQ

diacylglycerol kinase theta

involved_in

GO_REF:0000107

NCBI chr27:47,804,904...47,819,291
Ensembl chr27:47,805,017...47,817,583

DNTT

DNA nucleotidylexotransferase

NCBI chr 9:89,459,347...89,494,985
Ensembl chr 9:89,458,820...89,497,013

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

(PMID:25644539)

NCBI chr13:41,670,416...41,755,549

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

NCBI chr 9:88,921,826...89,034,418
Ensembl chr 9:88,922,007...89,032,880

heat shock protein family D (Hsp60) member 1

NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363

IL1B

interleukin 1 beta

acts_upstream_of_or_within

(PMID:18490713)
(PMID:15905573), (PMID:16301672), (PMID:18490713)

PMID:15905573 PMID:16301672 PMID:18490713

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

potassium inwardly rectifying channel subfamily J member 11

involved_in

GO_REF:0000107

NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801

KCNJ8

potassium inwardly rectifying channel subfamily J member 8

involved_in
acts_upstream_of_or_within

(PMID:21984445), (PMID:26142302)

PMID:21984445 PMID:26142302

GO_REF:0000107

NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042

LOC119623289

diacylglycerol kinase theta

involved_in

GO_REF:0000107

NT5E

5'-nucleotidase ecto

involved_in

(PMID:25644539)

NCBI chr13:10,115,591...10,162,178
Ensembl chr13:10,116,161...10,160,414

P2RX1

purinergic receptor P2X 1

involved_in
acts_upstream_of_or_within

PMID:14679185 PMID:14722245

(PMID:14679185), (PMID:14722245)

InterPro
MGI

GO_REF:0000002

NCBI chr16:3,377,526...3,399,374
Ensembl chr16:3,377,483...3,398,360

P2RX2

purinergic receptor P2X 2

involved_in
acts_upstream_of_or_within

PMID:15572362 PMID:15961431

(PMID:15572362), (PMID:15961431)
(PMID:15961431)

InterPro
MGI

GO_REF:0000002

NCBI chr11:127,961,004...127,964,529
Ensembl chr11:127,961,079...127,964,113

purinergic receptor P2X 3

acts_upstream_of_or_within

(PMID:11069182)
(PMID:11069181), (PMID:11466438), (PMID:12813150), (PMID:17074061)
(PMID:15961431)

PMID:11069181 PMID:11069182 PMID:11466438 PMID:12813150 PMID:15961431 More...

NCBI chr 1:15,872,124...15,906,452

purinergic receptor P2X 3

involved_in

Ensembl
InterPro

GO_REF:0000002 GO_REF:0000107

Ensembl chr 1:15,893,197...15,906,116

P2RX4

purinergic receptor P2X 4

involved_in

GO_REF:0000002

NCBI chr11:116,585,276...116,609,401
Ensembl chr11:116,585,586...116,609,511

P2RX5

purinergic receptor P2X 5

involved_in

RGD
InterPro

PMID:12237343

GO_REF:0000002 RGD:727431

NCBI chr16:3,173,215...3,198,262
Ensembl chr16:3,180,595...3,196,341

P2RX6

purinergic receptor P2X 6

involved_in

GO_REF:0000002

NCBI chr19:4,958,713...4,969,443
Ensembl chr19:4,958,671...4,969,724

purinergic receptor P2X 7

involved_in
acts_upstream_of_or_within

(PMID:15240711), (PMID:15713258)
(PMID:11544318), (PMID:18490713)
(PMID:11016935), (PMID:12055263), (PMID:14761980), (PMID:15937334), (PMID:15978588), (PMID:16116196), (PMID:16198349), (PMID:17135244), (PMID:17286969), (PMID:18082965), (PMID:18097031), (PMID:18519738)
(PMID:16325464), (PMID:17448897)

InterPro
MGI
Ensembl

PMID:11016935 PMID:11544318 PMID:12055263 PMID:14761980 PMID:15240711 More...

GO_REF:0000002 GO_REF:0000107

NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059

PANX1

pannexin 1

involved_in
acts_upstream_of_or_within

(PMID:18490713)

PMID:18490713

GO_REF:0000107

NCBI chr 1:85,356,507...85,413,146
Ensembl chr 1:85,356,610...85,409,275

pyruvate kinase L/R

NCBI chr20:8,540,228...8,547,184
Ensembl chr20:8,540,763...8,545,884

PLCG2

phospholipase C gamma 2

NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990

PTEN

phosphatase and tensin homolog

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

SELL

selectin L

acts_upstream_of_or_within

(PMID:15914561)

PMID:15914561

NCBI chr25:59,345,080...59,365,684
Ensembl chr25:59,345,069...59,366,946

SLC8A1

solute carrier family 8 member A1

NCBI chr14:66,813,523...67,210,261

sphingosine kinase 1

NCBI chr16:45,290,147...45,295,175
Ensembl chr16:45,290,421...45,293,128

TRPC3

transient receptor potential cation channel subfamily C member 3

involved_in

GO_REF:0000107

NCBI chr 7:69,160,569...69,233,322
Ensembl chr 7:69,158,867...69,231,858

response to benzene

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ALAS2

5'-aminolevulinate synthase 2

NCBI chr X:51,086,062...51,108,564
Ensembl chr X:51,086,066...51,103,505

BCL2 associated agonist of cell death

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

BAG cochaperone 1

NCBI chr12:47,006,177...47,016,177

PDIA3

protein disulfide isomerase family A member 3

NCBI chr26:39,273,982...39,300,170
Ensembl chr26:39,272,997...39,349,966

PSMB9

proteasome 20S subunit beta 9

1,3-dinitrobenzene

NCBI chr17:39,246,356...39,251,852
Ensembl chr17:39,245,854...39,251,842

RAPGEF4

Rap guanine nucleotide exchange factor 4

NCBI chr10:58,233,503...58,549,337
Ensembl chr10:58,233,654...58,549,331

response to benzoic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DDX4

DEAD-box helicase 4

mono-(2-ethylhexyl) phthalate

NCBI chr 4:51,984,753...52,058,425
Ensembl chr 4:51,986,338...52,057,813

NR0B1

nuclear receptor subfamily 0 group B member 1

mono-(2-ethylhexyl) phthalate

NCBI chr X:28,707,698...28,713,158
Ensembl chr X:28,707,699...28,712,708

POU5F1

POU class 5 homeobox 1

mono-(2-ethylhexyl) phthalate

NCBI chr17:41,306,523...41,313,065

RBP1

retinol binding protein 1

mono-(2-ethylhexyl) phthalate

NCBI chr15:51,011,664...51,033,963

steroidogenic acute regulatory protein

mono-(2-ethylhexyl) phthalate

NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583

WNT4

Wnt family member 4

mono-(2-ethylhexyl) phthalate

NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203

response to bile acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

5'-aminolevulinate synthase 1

involved_in

(PMID:17975826)

PMID:17975826

NCBI chr22:13,558,011...13,573,740
Ensembl chr22:13,559,180...13,575,869

FGFR4

fibroblast growth factor receptor 4

NOT|involved_in

(PMID:19085950)

PMID:19085950

NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456

VDR

vitamin D receptor

involved_in

GO_REF:0000107

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

response to biotin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HLCS

holocarboxylase synthetase

involved_in

PMID:16359899

GO_REF:0000107 RGD:2313678

NCBI chr 2:80,729,064...80,973,188
Ensembl chr 2:80,732,210...80,954,071

OTC

ornithine transcarbamylase

NCBI chr X:35,494,334...35,570,923
Ensembl chr X:35,494,287...35,570,845

response to biphenyl

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

albumin

NCBI chr 7:21,872,036...21,890,095
Ensembl chr 7:21,876,132...21,891,407

calreticulin

NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792

DMBT1

deleted in malignant brain tumors 1

NCBI chr 9:115,344,861...115,346,308

HNF1 homeobox B

PCB Arochlor 1254

NCBI chr16:30,033,486...30,097,106
Ensembl chr16:30,036,766...30,097,088

squalene epoxidase

NCBI chr 8:119,586,639...119,610,980
Ensembl chr 8:119,586,659...119,611,142

steroid 5 alpha-reductase 2

NCBI chr14:75,915,495...75,971,280
Ensembl chr14:75,917,260...75,970,365

response to bisphenol A

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DNA methyltransferase 1

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

estrogen receptor 2

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

FTO

FTO alpha-ketoglutarate dependent dioxygenase

NCBI chr 5:39,487,304...39,900,238
Ensembl chr 5:39,487,418...39,725,747

MC4R

melanocortin 4 receptor

NCBI chr18:19,380,054...19,386,412
Ensembl chr18:19,380,849...19,381,847

response to brassinosteroid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

hexokinase 1

NCBI chr 9:61,917,501...62,029,737
Ensembl chr 9:61,917,440...62,001,843

response to caffeine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA2A

adenosine A2a receptor

NCBI chr19:7,691,678...7,706,781
Ensembl chr19:7,691,536...7,706,926

BCL2 apoptosis regulator

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914

DHODH

dihydroorotate dehydrogenase (quinone)

NCBI chr 5:55,161,788...55,177,383
Ensembl chr 5:55,161,916...55,180,896

DNA methyltransferase 1

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

DNA methyltransferase 3 beta

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

NCBI chr 9:88,921,826...89,034,418
Ensembl chr 9:88,922,007...89,032,880

FKBP1A

FKBP prolyl isomerase 1A

acts_upstream_of_or_within

(PMID:15289441)

PMID:15289441

NCBI chr 2:55,170,816...55,195,380

GNAL

G protein subunit alpha L

acts_upstream_of_or_within

(PMID:11404425)

PMID:11404425

NCBI chr18:69,508,254...69,699,628
Ensembl chr18:69,510,512...69,635,000

HDAC1

histone deacetylase 1

NCBI chr20:100,529,782...100,575,953
Ensembl chr20:100,530,369...100,558,556

histone deacetylase 2

NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742

insulin like growth factor 1

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

IL6

interleukin 6

Cell shortening response decreased

PMID:15845578

RGD:2306941

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

IRS1

insulin receptor substrate 1

PMID:21940847 PMID:22995397

RGD:6483017 RGD:8661261

NCBI chr10:112,748,283...112,812,368

peroxisome proliferator activated receptor gamma

NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418

PRKAA1

protein kinase AMP-activated catalytic subunit alpha 1

NCBI chr 4:39,516,307...39,553,627

PRKAA2

protein kinase AMP-activated catalytic subunit alpha 2

NCBI chr20:76,258,063...76,319,512
Ensembl chr20:76,259,763...76,319,430

RYR1

ryanodine receptor 1

involved_in

PMID:19116207

NCBI chr 6:33,080,443...33,234,478
Ensembl chr 6:33,080,758...33,213,788

RYR2

ryanodine receptor 2

involved_in
acts_upstream_of_or_within

(PMID:14593104)

PMID:14593104

GO_REF:0000107

NCBI chr25:74,169,024...74,951,371
Ensembl chr25:74,389,122...74,953,451

syndecan 2

NCBI chr 8:91,451,808...91,570,778
Ensembl chr 8:91,552,647...91,568,828

tumor protein p53

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

response to cAMP

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aralkylamine N-acetyltransferase

NCBI chr16:45,206,233...45,215,761
Ensembl chr16:45,206,377...45,207,591

AGXT

alanine--glyoxylate and serine--pyruvate aminotransferase

NCBI chr10:126,933,711...126,943,980
Ensembl chr10:126,933,835...126,944,354

5'-aminolevulinate synthase 1

NCBI chr22:13,558,011...13,573,740
Ensembl chr22:13,559,180...13,575,869

ALDH3A1

aldehyde dehydrogenase 3 family member A1

NCBI chr16:18,302,145...18,312,768
Ensembl chr16:18,302,142...18,312,756

ALDOB

aldolase, fructose-bisphosphate B

NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258

amphiregulin

NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162

ATP7B

ATPase copper transporting beta

NCBI chr 3:29,817,712...29,899,302
Ensembl chr 3:29,816,860...29,899,077

BCKDHA

branched chain keto acid dehydrogenase E1 subunit alpha

NCBI chr 6:35,717,679...35,747,245
Ensembl chr 6:35,717,694...35,751,098

BCKDHB

branched chain keto acid dehydrogenase E1 subunit beta

NCBI chr13:4,845,481...5,087,558
Ensembl chr13:4,845,457...5,087,745

BCL2 apoptosis regulator

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

BIRC2

baculoviral IAP repeat containing 2

NCBI chr 1:93,721,449...93,746,638

BRAF

B-Raf proto-oncogene, serine/threonine kinase

NCBI chr21:109,495,525...109,690,261

BSG

basigin (Ok blood group)

NCBI chr 6:309,579...320,209
Ensembl chr 6:309,506...321,785

complement C1s

NCBI chr11:7,106,769...7,115,055
Ensembl chr11:7,139,115...7,148,056
Ensembl chr11:7,139,115...7,148,056

coactivator associated arginine methyltransferase 1

NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682

cyclin D2

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

CDK2

cyclin dependent kinase 2

NCBI chr11:51,905,085...51,910,209
Ensembl chr11:51,905,115...51,909,907

CDO1

cysteine dioxygenase type 1

NCBI chr23:19,049,612...19,061,783
Ensembl chr23:19,049,262...19,061,740

CITED1

Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1

involved_in

(MGI:4410428|PMID:18187554)

PMID:18187554

MGI:4410428

NCBI chr X:62,126,383...62,131,919
Ensembl chr X:62,126,320...62,130,220

CNGA3

cyclic nucleotide gated channel subunit alpha 3

NCBI chr14:2,039,281...2,124,527
Ensembl chr14:2,096,232...2,123,231

collagen type I alpha 1 chain

NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930

carbamoyl-phosphate synthase 1

PMID:6092398 PMID:17397987

RGD:2303516 RGD:2303523

NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206

CREM

cAMP responsive element modulator

involved_in

(MGI:5494765|PMID:23443664)

PMID:23443664

MGI:5494765

NCBI chr 9:34,418,956...34,503,774
Ensembl chr 9:34,418,947...34,506,930

cytochrome P450 family 11 subfamily A member 1

NCBI chr26:9,122,008...9,151,844

CYP17A1

cytochrome P450 family 17 subfamily A member 1

NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180

CYP27B1

cytochrome P450 family 27 subfamily B member 1

NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443

CYP7B1

cytochrome P450 family 7 subfamily B member 1

NCBI chr 8:60,496,607...60,691,457
Ensembl chr 8:60,496,733...60,524,238

DGKQ

diacylglycerol kinase theta

involved_in

GO_REF:0000107

NCBI chr27:47,804,904...47,819,291
Ensembl chr27:47,805,017...47,817,583

DUOX1

dual oxidase 1

involved_in

GO_REF:0000107

NCBI chr26:38,038,093...38,073,993
Ensembl chr26:38,038,771...38,072,023

DUOX2

dual oxidase 2

involved_in

(PMID:15062544)

PMID:15062544

NCBI chr26:38,090,053...38,110,781
Ensembl chr26:38,090,648...38,109,636

dual specificity phosphatase 1

NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532

Fos proto-oncogene, AP-1 transcription factor subunit

NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514

FosB proto-oncogene, AP-1 transcription factor subunit

NCBI chr 6:38,916,039...38,924,129

FOS like 1, AP-1 transcription factor subunit

NCBI chr 1:8,356,263...8,365,606
Ensembl chr 1:8,356,836...8,364,918

FOS like 2, AP-1 transcription factor subunit

NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373

forkhead box M1

NCBI chr11:2,920,903...2,941,011
Ensembl chr11:2,920,663...2,940,823

GATA6

GATA binding protein 6

NCBI chr18:58,312,328...58,345,472
Ensembl chr18:58,311,482...58,343,746

GUCD1

guanylyl cyclase domain containing 1

NCBI chr19:7,578,125...7,589,196
Ensembl chr19:7,583,642...7,591,253

HMGA1

high mobility group AT-hook 1

acts_upstream_of_or_within

(PMID:19460132)

PMID:19460132

NCBI chr17:37,848,110...37,857,835
Ensembl chr17:37,849,412...37,853,880

3-hydroxy-3-methylglutaryl-CoA synthase 2

NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016

HNF4A

hepatocyte nuclear factor 4 alpha

NCBI chr 2:19,390,870...19,466,300
Ensembl chr 2:19,388,891...19,421,664

IL6R

interleukin 6 receptor

NCBI chr20:9,345,723...9,418,963
Ensembl chr20:9,361,152...9,396,610

JUN

Jun proto-oncogene, AP-1 transcription factor subunit

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

JunB proto-oncogene, AP-1 transcription factor subunit

NCBI chr 6:11,479,108...11,480,942
Ensembl chr 6:11,479,407...11,480,450

LDHA

lactate dehydrogenase A

NCBI chr 1:46,525,090...46,542,587

LOC103242912

nucleoside diphosphate kinase A

NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616

LOC119623289

diacylglycerol kinase theta

involved_in

GO_REF:0000107

MAT2A

methionine adenosyltransferase 2A

NCBI chr14:21,609,533...21,615,822
Ensembl chr14:21,611,040...21,615,615

MMP19

matrix metallopeptidase 19

NCBI chr11:51,786,076...51,794,325

NDUFS4

NADH:ubiquinone oxidoreductase subunit S4

involved_in

GO_REF:0000107

NCBI chr 4:49,851,012...49,967,533
Ensembl chr 4:49,851,014...49,967,590

oxytocin/neurophysin I prepropeptide

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

paired box 4

NCBI chr21:96,425,496...96,435,846
Ensembl chr21:96,425,656...96,429,874

PEBP1

phosphatidylethanolamine binding protein 1

NCBI chr11:113,469,845...113,479,177

PER1

period circadian regulator 1

involved_in

GO_REF:0000107

NCBI chr16:7,520,122...7,536,176
Ensembl chr16:7,520,006...7,531,940

PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

NCBI chr X:51,015,810...51,077,444
Ensembl chr X:51,016,318...51,071,977

phosphoinositide-3-kinase regulatory subunit 1

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

pyruvate kinase L/R

NCBI chr20:8,540,228...8,547,184
Ensembl chr20:8,540,763...8,545,884

PLA2G5

phospholipase A2 group V

NCBI chr20:112,465,341...112,487,082
Ensembl chr20:112,464,033...112,487,089

PLAT

plasminogen activator, tissue type

NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555

PNPT1

polyribonucleotide nucleotidyltransferase 1

NCBI chr14:51,211,385...51,267,706
Ensembl chr14:51,211,118...51,267,098

PPARGC1B

PPARG coactivator 1 beta

NCBI chr23:52,337,802...52,462,553
Ensembl chr23:52,428,052...52,455,089

PTK2B

protein tyrosine kinase 2 beta

NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782

PTPRN

protein tyrosine phosphatase receptor type N

NCBI chr10:105,196,508...105,216,665
Ensembl chr10:105,196,505...105,216,525

PYGM

glycogen phosphorylase, muscle associated

NCBI chr 1:9,474,539...9,490,612
Ensembl chr 1:9,475,622...9,491,500

RELA proto-oncogene, NF-kB subunit

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

renin

NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420

syndecan 1

NCBI chr14:87,499,732...87,523,122
Ensembl chr14:87,499,574...87,525,026

surfactant protein B

NCBI chr14:21,487,424...21,497,491
Ensembl chr14:21,488,387...21,499,850

surfactant protein C

NCBI chr 8:20,229,756...20,233,568
Ensembl chr 8:20,230,870...20,234,020

SLC6A3

solute carrier family 6 member 3

NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866

SPARC

secreted protein acidic and cysteine rich

NCBI chr23:54,224,003...54,248,869
Ensembl chr23:54,222,838...54,238,006

SREBF1

sterol regulatory element binding transcription factor 1

NCBI chr16:16,847,603...16,874,239
Ensembl chr16:16,845,491...16,859,554

signal transducer and activator of transcription 1

NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393

thrombomodulin

NCBI chr 2:52,041,950...52,045,946
Ensembl chr 2:52,043,746...52,045,626

DNA topoisomerase I

NCBI chr 2:22,655,085...22,751,082
Ensembl chr 2:22,651,995...22,751,102

tyrosinase

NCBI chr 1:80,330,051...80,444,646

VGF

VGF nerve growth factor inducible

involved_in

GO_REF:0000107

NCBI chr28:12,016,216...12,021,151
Ensembl chr28:12,018,800...12,020,647

response to capsazepine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TRPV1

transient receptor potential cation channel subfamily V member 1

involved_in

GO_REF:0000107

NCBI chr16:3,071,158...3,091,068
Ensembl chr16:3,071,526...3,090,330

response to catecholamine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADRB2

adrenoceptor beta 2

involved_in

NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401

RNLS

renalase, FAD dependent amine oxidase

NCBI chr 9:81,725,115...82,029,361

response to cGMP

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACP2

acid phosphatase 2, lysosomal

NCBI chr 1:18,061,094...18,070,929
Ensembl chr 1:18,060,994...18,072,208

renin

NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420

TLR7

toll like receptor 7

involved_in

(PMID:35477763)

PMID:35477763

NCBI chr X:11,348,520...11,372,132

response to cholesterol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCA2

ATP binding cassette subfamily A member 2

involved_in

(PMID:11178988)

PMID:11178988

NCBI chr12:1,161,340...1,183,807
Ensembl chr12:1,162,865...1,183,113

ACP5

acid phosphatase 5, tartrate resistant

NCBI chr 6:10,488,572...10,493,508
Ensembl chr 6:10,488,460...10,491,519

ACSL5

acyl-CoA synthetase long chain family member 5

NCBI chr 9:105,259,546...105,311,500
Ensembl chr 9:105,257,429...105,311,690

C-C motif chemokine ligand 5

NCBI chr16:29,351,214...29,361,317

CCR5

C-C motif chemokine receptor 5

involved_in

GO_REF:0000107

NCBI chr22:7,803,794...7,818,112

CYP8B1

cytochrome P450 family 8 subfamily B member 1

NCBI chr22:4,323,840...4,326,459
Ensembl chr22:4,324,396...4,325,901

coagulation factor VII

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

FDPS

farnesyl diphosphate synthase

NCBI chr20:8,514,311...8,526,363

HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

NCBI chr 4:69,664,784...69,690,343
Ensembl chr 4:69,665,417...69,688,686

3-hydroxy-3-methylglutaryl-CoA synthase 1

PMID:2903839 PMID:3670308

RGD:2326164 RGD:728568

NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409

LOC103242767

C-C motif chemokine 3

involved_in

(PMID:19523456)

PMID:19523456

NCBI chr16:29,887,799...29,897,664
Ensembl chr16:29,887,883...29,897,544

NR1H3

nuclear receptor subfamily 1 group H member 3

NCBI chr 1:18,041,495...18,061,196
Ensembl chr 1:18,041,830...18,051,501

nuclear receptor subfamily 1 group H member 4

NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293

PMVK

phosphomevalonate kinase

involved_in

(PMID:10191291)

PMID:10191291

NCBI chr20:8,893,297...8,906,882
Ensembl chr20:8,894,786...8,906,873

SMAD2

SMAD family member 2

involved_in

(PMID:17878231)

PMID:17878231

NCBI chr18:33,017,138...33,105,320
Ensembl chr18:33,017,492...33,104,606

transforming growth factor beta 1

involved_in

GO_REF:0000107

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

TGFBR1

transforming growth factor beta receptor 1

involved_in

(PMID:17878231)
(MGI:3766844|PMID:17878231)

PMID:17878231

MGI:3766844

NCBI chr12:40,272,507...40,321,740
Ensembl chr12:40,276,916...40,297,372

TGFBR2

transforming growth factor beta receptor 2

involved_in

GO_REF:0000107

NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711

response to cobalamin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD40 molecule

NCBI chr 2:17,753,713...17,765,134
Ensembl chr 2:17,753,394...17,764,566

CD40 ligand

NCBI chr X:111,655,301...111,667,602
Ensembl chr X:111,655,397...111,666,639

epidermal growth factor receptor

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

RELA proto-oncogene, NF-kB subunit

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

serine dehydratase

NCBI chr11:108,643,198...108,654,927
Ensembl chr11:108,642,694...108,654,620

response to cocaine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABAT

4-aminobutyrate aminotransferase

NCBI chr 5:8,274,310...8,380,973
Ensembl chr 5:8,315,952...8,379,549

ADGRL3

adhesion G protein-coupled receptor L3

involved_in

(MGI:5430447|PMID:22575564)

PMID:22575564

MGI:5430447

NCBI chr 7:6,726,400...7,261,059

ADRA1A

adrenoceptor alpha 1A

RGD:11556240 (All species) (All species)

PMID:8746923

NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125

AGO2

argonaute RISC catalytic component 2

NCBI chr 8:134,761,651...134,855,971
Ensembl chr 8:134,767,182...134,823,070

ARC

activity regulated cytoskeleton associated protein

NCBI chr 8:136,857,402...136,860,933
Ensembl chr 8:136,859,438...136,860,628

BAX

BCL2 associated X, apoptosis regulator

NCBI chr 6:42,186,028...42,193,105

CACNG4

calcium voltage-gated channel auxiliary subunit gamma 4

NCBI chr16:54,413,981...54,482,707
Ensembl chr16:54,413,965...54,482,561

CDK5

cyclin dependent kinase 5

acts_upstream_of_or_within

(PMID:14769920)

PMID:14769920

NCBI chr21:119,235,687...119,240,163

CHRNB2

cholinergic receptor nicotinic beta 2 subunit

acts_upstream_of_or_within

(PMID:11282258)

PMID:11282258

NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795

CNR1

cannabinoid receptor 1

NCBI chr13:12,626,259...12,653,253
Ensembl chr13:12,630,270...12,631,688

cAMP responsive element binding protein 1

NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832

corticotropin releasing hormone

NCBI chr 8:62,052,155...62,056,424
Ensembl chr 8:62,052,592...62,053,182

dynamin 2

NCBI chr 6:9,718,014...9,830,061
Ensembl chr 6:9,718,244...9,831,206

DNMT3A

DNA methyltransferase 3 alpha

NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819

DNA methyltransferase 3 beta

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

DPYSL2

dihydropyrimidinase like 2

NCBI chr 8:24,625,961...24,772,047
Ensembl chr 8:24,690,856...24,772,087

dopamine receptor D1

involved_in
acts_upstream_of_or_within

(PMID:9387887)
(PMID:10661513), (PMID:12354293), (PMID:16908842), (PMID:18045908)
(PMID:10222120)

PMID:9387887 PMID:10222120 PMID:10661513 PMID:12354293 PMID:16908842 More...

GO_REF:0000107

NCBI chr23:77,587,340...77,591,434

dopamine receptor D2

involved_in
acts_upstream_of_or_within

(PMID:12185400)
(PMID:11923462)
(PMID:18671743)

PMID:11923462 PMID:12185400 PMID:18671743

GO_REF:0000107

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

involved_in
acts_upstream_of_or_within

(PMID:10415668)
(PMID:10943692)

PMID:10415668 PMID:10943692

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

dopamine receptor D5

involved_in
acts_upstream_of_or_within

(PMID:12768268)

PMID:12768268

GO_REF:0000107

NCBI chr27:40,267,681...40,270,061
Ensembl chr27:40,268,235...40,269,671

EFTUD2

elongation factor Tu GTP binding domain containing 2

NCBI chr16:61,505,796...61,549,720
Ensembl chr16:61,505,825...61,551,890

early growth response 1

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

ELAVL4

ELAV like RNA binding protein 4

NCBI chr20:82,712,987...82,869,013
Ensembl chr20:82,712,944...82,806,387

FADD

Fas associated via death domain

NCBI chr 1:4,358,314...4,361,863

FKBP5

FKBP prolyl isomerase 5

NCBI chr17:36,432,595...36,551,233
Ensembl chr17:36,481,024...36,552,456

FMR1

Fragile X messenger ribonucleoprotein 1

NCBI chr X:122,635,383...122,674,298
Ensembl chr X:122,635,439...122,674,355

FosB proto-oncogene, AP-1 transcription factor subunit

PMID:17572394 PMID:22403532 PMID:23665060 PMID:27664298

RGD:401851078 RGD:401851084 RGD:401900166 RGD:401900302

NCBI chr 6:38,916,039...38,924,129

GAD1

glutamate decarboxylase 1

NCBI chr10:56,351,495...56,396,476
Ensembl chr10:56,353,253...56,396,524

GAD2

glutamate decarboxylase 2

NCBI chr 9:25,906,047...25,993,715
Ensembl chr 9:25,906,103...25,995,489

glutamate ionotropic receptor AMPA type subunit 1

PMID:15548228 PMID:20600170 PMID:21613507

RGD:405096667 RGD:405100712 RGD:4107066

NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849

GRIN2A

glutamate ionotropic receptor NMDA type subunit 2A

NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828

glutamate ionotropic receptor NMDA type subunit 2B

NCBI chr11:13,444,155...13,873,034
Ensembl chr11:13,456,968...13,873,202

GRK5

G protein-coupled receptor kinase 5

NCBI chr 9:111,996,780...112,249,247
Ensembl chr 9:111,996,599...112,244,570

GRM2

glutamate metabotropic receptor 2

NCBI chr22:13,044,974...13,056,469
Ensembl chr22:13,046,641...13,056,453

histone deacetylase 2

NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742

HDAC5

histone deacetylase 5

acts_upstream_of_or_within

PMID:17988634 PMID:21954104

(PMID:17988634)

RGD
MGI

RGD:9681462

NCBI chr16:62,267,837...62,314,914
Ensembl chr16:62,274,041...62,315,094

HNMT

histamine N-methyltransferase

NCBI chr10:22,188,151...22,238,665
Ensembl chr10:22,188,110...22,238,671

HOMER1

homer scaffold protein 1

NCBI chr 4:73,591,105...73,729,680
Ensembl chr 4:73,589,495...73,728,353

HSP90AA1

heat shock protein 90 alpha family class A member 1

NCBI chr24:80,016,352...80,019,130
Ensembl chr24:80,016,232...80,019,120

HSP90AB1

heat shock protein 90 alpha family class B member 1

NCBI chr17:27,914,261...27,921,666
Ensembl chr17:27,911,013...27,921,251

HSPA5

heat shock protein family A (Hsp70) member 5

NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431

heat shock protein family D (Hsp60) member 1

NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363

HTR1B

5-hydroxytryptamine receptor 1B

NCBI chr13:2,143,646...2,145,943
Ensembl chr13:2,144,313...2,145,485

HTR2A

5-hydroxytryptamine receptor 2A

NCBI chr 3:24,820,029...24,884,472
Ensembl chr 3:24,820,035...24,883,432

HTR3A

5-hydroxytryptamine receptor 3A

NCBI chr 1:105,359,139...105,375,217
Ensembl chr 1:105,359,730...105,374,664

LOC103216935

uncharacterized LOC103216935

NCBI chr10:11,470,295...11,558,688
Ensembl chr10:11,475,221...11,479,475

mitogen-activated protein kinase 1

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

MBD1

methyl-CpG binding domain protein 1

NCBI chr18:30,675,419...30,690,111
Ensembl chr18:30,675,653...30,685,946

MDM2 proto-oncogene

NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890

methyl-CpG binding protein 2

PMID:20711185 PMID:23688924

RGD:12789445 RGD:9589062

NCBI chr X:128,445,028...128,519,892
Ensembl chr X:128,453,577...128,455,785

MTOR

mechanistic target of rapamycin kinase

NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020

MYRF

myelin regulatory factor

NCBI chr 1:12,066,277...12,103,091

NCAM1

neural cell adhesion molecule 1

NCBI chr 1:104,332,622...104,647,258

NEFH

neurofilament heavy chain

NCBI chr19:12,357,982...12,375,449

neurotensin

NCBI chr11:81,270,147...81,278,327
Ensembl chr11:81,270,593...81,277,713

OPRK1

opioid receptor kappa 1

PMID:9645969 PMID:10554970

RGD:9831419 RGD:9831421

NCBI chr 8:49,337,308...49,364,724
Ensembl chr 8:49,341,427...49,362,947

opioid receptor mu 1

NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088

oxytocin/neurophysin I prepropeptide

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

oxytocin receptor

NCBI chr22:44,746,108...44,764,501
Ensembl chr22:44,742,419...44,763,243

progesterone receptor

NCBI chr 1:92,420,970...92,519,128
Ensembl chr 1:92,430,453...92,517,296

PITX3

paired like homeodomain 3

NCBI chr 9:95,266,257...95,278,333
Ensembl chr 9:95,266,582...95,268,139

protein phosphatase 1 regulatory subunit 15A

protein phosphatase 1 regulatory inhibitor subunit 1B

NCBI chr16:66,530,640...66,541,025
Ensembl chr16:66,530,488...66,541,242

prolactin

NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631

PTK2B

protein tyrosine kinase 2 beta

NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782

RGS4

regulator of G protein signaling 4

NCBI chr25:65,729,344...65,735,278
Ensembl chr25:65,726,394...65,735,381

sirtuin 1

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

sirtuin 2

NCBI chr 6:33,493,106...33,518,793
Ensembl chr 6:33,493,079...33,518,647

SLC18A2

solute carrier family 18 member A2

NCBI chr 9:110,039,783...110,078,822
Ensembl chr 9:110,040,391...110,076,647

solute carrier family 6 member 1

NCBI chr22:47,033,436...47,076,785
Ensembl chr22:47,033,467...47,078,844

SLC6A3

solute carrier family 6 member 3

acts_upstream_of_or_within

(PMID:18671743)

PMID:18671743

NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866

SMPD1

sphingomyelin phosphodiesterase 1

NCBI chr 1:58,431,677...58,436,233
Ensembl chr 1:58,432,068...58,436,236

synuclein alpha

NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479

synuclein gamma

NCBI chr 9:44,907,840...44,914,750
Ensembl chr 9:44,907,728...44,912,510

ST8SIA2

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

NCBI chr29:10,966,738...11,039,014
Ensembl chr29:11,000,989...11,041,634

TACR3

tachykinin receptor 3

NCBI chr 7:51,662,248...51,764,058
Ensembl chr 7:51,665,147...51,762,390

TIAM1

TIAM Rac1 associated GEF 1

NCBI chr 2:60,573,187...61,015,599
Ensembl chr 2:60,865,819...61,017,191

TUB

TUB bipartite transcription factor

NCBI chr 1:56,699,044...56,764,162
Ensembl chr 1:56,699,408...56,783,126

ubiquitin protein ligase E3A

NCBI chr26:56,638,936...56,738,555
Ensembl chr26:56,666,162...56,736,737

response to codeine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

response to corticosteroid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SOX30

SRY-box transcription factor 30

involved_in

(PMID:18436822)

PMID:18436822

NCBI chr23:60,013,384...60,038,682
Ensembl chr23:60,014,046...60,037,997

response to corticosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aralkylamine N-acetyltransferase

NCBI chr16:45,206,233...45,215,761
Ensembl chr16:45,206,377...45,207,591

AGTR1

angiotensin II receptor type 1

NCBI chr15:41,957,826...42,002,776

AVPR1A

arginine vasopressin receptor 1A

NCBI chr11:59,074,699...59,079,710
Ensembl chr11:59,071,202...59,079,596

BAX

BCL2 associated X, apoptosis regulator

NCBI chr 6:42,186,028...42,193,105

BCL2 apoptosis regulator

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

BDH1

3-hydroxybutyrate dehydrogenase 1

NCBI chr15:89,678,844...89,741,848
Ensembl chr15:89,707,046...89,742,434

calmodulin 2

NCBI chr14:60,027,884...60,042,041
Ensembl chr14:60,027,801...60,044,951
Ensembl chr 6:60,027,801...60,044,951
Ensembl chr24:60,027,801...60,044,951

cyclin D1

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

cyclin E1

NCBI chr 6:24,879,923...24,888,985

cyclin dependent kinase inhibitor 1A

NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342

catechol-O-methyltransferase

acts_upstream_of_or_within

(PMID:19770404), (PMID:22192380)

PMID:19770404 PMID:22192380

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

corticotropin releasing hormone

NCBI chr 8:62,052,155...62,056,424
Ensembl chr 8:62,052,592...62,053,182

cytochrome P450 family 11 subfamily A member 1

NCBI chr26:9,122,008...9,151,844

Fos proto-oncogene, AP-1 transcription factor subunit

NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514

FosB proto-oncogene, AP-1 transcription factor subunit

NCBI chr 6:38,916,039...38,924,129

FOS like 1, AP-1 transcription factor subunit

NCBI chr 1:8,356,263...8,365,606
Ensembl chr 1:8,356,836...8,364,918

GPX3

glutathione peroxidase 3

NCBI chr23:53,576,950...53,585,321

HDAC6

histone deacetylase 6

NCBI chr X:45,927,625...45,951,636
Ensembl chr X:45,928,092...45,952,929

hydroxysteroid 17-beta dehydrogenase 3

NCBI chr12:106,831,807...106,885,543
Ensembl chr12:106,832,034...106,886,385

HTR7

5-hydroxytryptamine receptor 7

NCBI chr 9:84,081,713...84,191,112
Ensembl chr 9:84,083,396...84,190,876

JunB proto-oncogene, AP-1 transcription factor subunit

NCBI chr 6:11,479,108...11,480,942
Ensembl chr 6:11,479,407...11,480,450

monoamine oxidase B

NCBI chr X:40,936,789...41,054,547
Ensembl chr X:40,936,711...41,054,641

mitofusin 1

NCBI chr15:10,050,616...10,093,118
Ensembl chr15:10,047,599...10,093,126

NEFL

neurofilament light chain

NCBI chr 8:23,077,085...23,083,213
Ensembl chr 8:23,077,086...23,083,222

nitric oxide synthase 3

NCBI chr21:119,174,829...119,196,840

nuclear receptor subfamily 3 group C member 1

PMID:10399770 PMID:16673181

RGD:401976290 RGD:4892105

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

NR3C2

nuclear receptor subfamily 3 group C member 2

NCBI chr 7:94,574,010...94,935,348

NTRK3

neurotrophic receptor tyrosine kinase 3

NCBI chr29:6,441,824...6,831,029
Ensembl chr29:6,447,256...6,830,526

neurotensin

NCBI chr11:81,270,147...81,278,327
Ensembl chr11:81,270,593...81,277,713

PEBP1

phosphatidylethanolamine binding protein 1

NCBI chr11:113,469,845...113,479,177

PRKCA

protein kinase C alpha

NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256

PRKN

parkin RBR E3 ubiquitin protein ligase

NCBI chr13:88,856,056...90,329,379

PTGS1

prostaglandin-endoperoxide synthase 1

NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315

reelin

NCBI chr21:72,440,988...72,951,173
Ensembl chr21:72,440,160...72,950,747

SERPINA7

serpin family A member 7

NCBI chr X:93,895,103...93,899,718
Ensembl chr X:93,894,788...93,898,738

SLC18A2

solute carrier family 18 member A2

NCBI chr 9:110,039,783...110,078,822
Ensembl chr 9:110,040,391...110,076,647

steroidogenic acute regulatory protein

NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583

tyrosine hydroxylase

NCBI chr 1:1,969,194...1,977,263
Ensembl chr 1:1,966,460...1,977,218

TRH

thyrotropin releasing hormone

NCBI chr22:51,075,814...51,079,852
Ensembl chr22:51,076,157...51,078,236

urocortin 3

NCBI chr 9:5,491,134...5,500,663
Ensembl chr 9:5,498,945...5,499,430

response to cortisol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914

IGFBP7

insulin like growth factor binding protein 7

NCBI chr 7:11,617,096...11,694,530

SLIT2

slit guidance ligand 2

involved_in

GO_REF:0000107

NCBI chr27:29,650,589...30,020,105
Ensembl chr27:29,650,337...29,803,612

SLIT3

slit guidance ligand 3

involved_in

GO_REF:0000107

NCBI chr23:70,890,096...71,524,002
Ensembl chr23:70,885,737...71,106,703

thymidine kinase 1

NCBI chr16:70,186,103...70,200,689
Ensembl chr16:70,186,767...70,200,610

response to cortisone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

galactosidase beta 1

NCBI chr15:77,480,895...77,592,130
Ensembl chr15:77,480,598...77,592,120

response to curcumin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP5F1B

ATP synthase F1 subunit beta

NCBI chr11:52,587,608...52,600,057
Ensembl chr11:52,587,143...52,600,756

ITGAM

integrin subunit alpha M

NCBI chr 5:27,957,162...28,042,697
Ensembl chr 5:27,957,324...28,042,691

OPA1

OPA1 mitochondrial dynamin like GTPase

NCBI chr15:87,679,656...87,778,767
Ensembl chr15:87,679,077...87,779,102

PLCG1

phospholipase C gamma 1

NCBI chr 2:22,599,547...22,638,394

PRKN

parkin RBR E3 ubiquitin protein ligase

NCBI chr13:88,856,056...90,329,379

response to cycloheximide

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BCL2L1

BCL2 like 1

acts_upstream_of_or_within

(PMID:9176392)

PMID:9176392

NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470

BORCS7

BLOC-1 related complex subunit 7

acts_upstream_of_or_within

(PMID:30067980)

PMID:30067980

NCBI chr 9:95,895,775...95,906,861
Ensembl chr 9:95,895,551...95,905,320

cytidine deaminase

NCBI chr20:111,931,365...111,960,172
Ensembl chr20:111,931,364...111,960,036

FGA

fibrinogen alpha chain

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

GHR

growth hormone receptor

NOT|involved_in

(PMID:9360546)

PMID:9360546

NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666

response to DDT

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cyclin B1

NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085

response to dehydroepiandrosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cAMP responsive element binding protein 1

NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832

PPARG coactivator 1 alpha

NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582

response to desipramine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synuclein alpha

NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479

synuclein gamma

NCBI chr 9:44,907,840...44,914,750
Ensembl chr 9:44,907,728...44,912,510

response to dexamethasone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

adrenoceptor beta 2

NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401

alpha fetoprotein

NCBI chr 7:21,904,225...21,924,105
Ensembl chr 7:21,905,154...21,924,092

ARNT

aryl hydrocarbon receptor nuclear translocator

CCAAT enhancer binding protein alpha

NCBI chr 6:28,342,506...28,345,759
Ensembl chr 6:28,343,907...28,344,977

claudin 1

NCBI chr15:84,518,464...84,533,587
Ensembl chr15:84,516,478...84,532,969

carbamoyl-phosphate synthase 1

NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206

cathepsin B

NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854

cytochrome P450 family 1 subfamily B member 1

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

CYP3A5

cytochrome P450 family 3 subfamily A member 5

NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507

endothelin 1

NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198

E1A binding protein p300

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

erythropoietin

NCBI chr28:12,487,222...12,491,986
Ensembl chr28:12,489,766...12,491,908

ERBB2

erb-b2 receptor tyrosine kinase 2

NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952

ERBB4

erb-b2 receptor tyrosine kinase 4

PMID:27133902 PMID:34189720

RGD:405650400 RGD:405650687

NCBI chr10:97,099,090...98,281,697

estrogen receptor 2

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

FIBIN

fin bud initiation factor homolog

involved_in

GO_REF:0000107

NCBI chr 1:38,103,138...38,105,267
Ensembl chr 1:38,104,089...38,104,724

forkhead box O3

NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725

GAD2

glutamate decarboxylase 2

NCBI chr 9:25,906,047...25,993,715
Ensembl chr 9:25,906,103...25,995,489

GBA1

glucosylceramidase beta 1

NCBI chr20:8,598,110...8,631,517
Ensembl chr20:8,598,628...8,630,990

GGCX

gamma-glutamyl carboxylase

NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885

GHRH

growth hormone releasing hormone

NCBI chr 2:26,482,734...26,493,761
Ensembl chr 2:26,487,973...26,493,499

GHSR

growth hormone secretagogue receptor

NCBI chr15:17,008,185...17,013,504
Ensembl chr15:17,009,369...17,012,618

HDAC3

histone deacetylase 3

NCBI chr23:44,246,296...44,263,127

HDAC6

histone deacetylase 6

NCBI chr X:45,927,625...45,951,636
Ensembl chr X:45,928,092...45,952,929

HNF4A

hepatocyte nuclear factor 4 alpha

NCBI chr 2:19,390,870...19,466,300
Ensembl chr 2:19,388,891...19,421,664

interleukin 1 beta

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

leptin receptor

NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229

LOC103246654

NADPH--cytochrome P450 reductase

NCBI chr28:10,145,070...10,230,836
Ensembl chr28:10,197,503...10,230,468

nitric oxide synthase 2

NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257

nuclear receptor subfamily 3 group C member 1

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

neuregulin 1

NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487

pappalysin 1

NCBI chr12:23,182,856...23,427,092
Ensembl chr12:23,184,704...23,427,165

PCK2

phosphoenolpyruvate carboxykinase 2, mitochondrial

NCBI chr24:1,077,206...1,087,306
Ensembl chr24:1,077,447...1,087,607

PCNA

proliferating cell nuclear antigen

NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316

phosphoinositide-3-kinase regulatory subunit 1

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

PTAFR

platelet activating factor receptor

NCBI chr20:104,627,591...104,658,840
Ensembl chr20:104,657,179...104,658,207

surfactant protein B

NCBI chr14:21,487,424...21,497,491
Ensembl chr14:21,488,387...21,499,850

TAT

tyrosine aminotransferase

NCBI chr 5:54,695,342...54,749,291
Ensembl chr 5:54,693,458...54,705,082

thioredoxin

NCBI chr12:29,296,166...29,308,979

uncoupling protein 2

NCBI chr 1:65,238,311...65,246,841
Ensembl chr 1:65,235,775...65,246,450

vascular endothelial growth factor A

NCBI chr17:28,377,959...28,394,508

response to differentiation-inducing factor 1

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EEF2K

eukaryotic elongation factor 2 kinase

involved_in

GO_REF:0000118

NCBI chr 5:19,871,669...19,957,471
Ensembl chr 5:19,871,310...19,957,395

response to diphenyl ether

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cytochrome P450 family 1 subfamily A member 1

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

response to dopamine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

catechol-O-methyltransferase

acts_upstream_of_or_within

(PMID:22169008)

PMID:22169008

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

fucose kinase

NCBI chr 5:53,606,693...53,634,749
Ensembl chr 5:53,615,958...53,637,550

response to dsDNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

interleukin 21

NCBI chr 7:69,859,793...69,872,237
Ensembl chr 7:69,863,535...69,872,025

response to dsRNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PELI1

pellino E3 ubiquitin protein ligase 1

involved_in
acts_upstream_of_or_within

(PMID:19734906)

PMID:19734906

GO_REF:0000107

NCBI chr14:42,864,857...42,930,315
Ensembl chr14:42,864,897...42,930,394

PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

involved_in

GO_REF:0000107

NCBI chr18:19,861,182...19,865,628
Ensembl chr18:19,862,743...19,865,250

TLR3

toll like receptor 3

poly(I:C) - a synthetic analog of double-stranded RNA, a molecular pattern associated with viral infection

PMID:16973131

RGD:1643119

NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232

response to estradiol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

ATP binding cassette subfamily C member 2

NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265

ABCC3

ATP binding cassette subfamily C member 3

NCBI chr16:42,646,316...42,703,124
Ensembl chr16:42,646,812...42,702,852

ACTR3

actin related protein 3

NCBI chr10:16,296,350...16,369,561
Ensembl chr10:16,297,502...16,369,220

ADCYAP1R1

ADCYAP receptor type I

NCBI chr21:27,274,039...27,333,316
Ensembl chr21:27,278,788...27,333,220

angiotensinogen

NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324

aryl hydrocarbon receptor

NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478

adenylate kinase 1

NCBI chr12:10,251,793...10,261,635
Ensembl chr12:10,256,054...10,261,465

ALDH1A1

aldehyde dehydrogenase 1 family member A1

NCBI chr12:83,949,529...84,092,452
Ensembl chr12:83,949,399...84,009,003

ALDH1A2

aldehyde dehydrogenase 1 family member A2

NCBI chr26:25,439,159...25,557,199
Ensembl chr26:25,439,360...25,557,202

aldehyde dehydrogenase 2 family member

NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374

ANXA1

annexin A1

involved_in

PMID:17283243

GO_REF:0000118 RGD:2306897

NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562

apolipoprotein B

NCBI chr14:86,624,209...86,669,175
Ensembl chr14:86,624,332...86,668,704

androgen receptor

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

AREG

amphiregulin

involved_in
acts_upstream_of_or_within

(PMID:17369357)

PMID:17369357

GO_REF:0000107

NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162

ARNT2

aryl hydrocarbon receptor nuclear translocator 2

NCBI chr26:2,790,059...2,990,760
Ensembl chr26:2,794,372...2,990,814

ARPC1B

actin related protein 2/3 complex subunit 1B

NCBI chr28:13,764,637...13,780,317

argininosuccinate synthase 1

NCBI chr12:7,643,484...7,701,334

aurora kinase A

NCBI chr 2:7,730,060...7,753,167
Ensembl chr 2:7,734,128...7,752,395

BCL2 associated agonist of cell death

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

BDH1

3-hydroxybutyrate dehydrogenase 1

NCBI chr15:89,678,844...89,741,848
Ensembl chr15:89,707,046...89,742,434

bone morphogenetic protein 4

PMID:16551644 PMID:23325243

RGD:2289005 RGD:8699509

NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225

BMP7

bone morphogenetic protein 7

NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944

BRCA1 DNA repair associated

NCBI chr16:63,162,827...63,243,928

BRCA2

BRCA2 DNA repair associated

NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213

complement C3

NCBI chr 6:6,250,422...6,289,264

CACNA1D

calcium voltage-gated channel subunit alpha1 D

NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101

calreticulin

NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792

caspase 3

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

caspase 6

NCBI chr 7:57,592,632...57,616,094
Ensembl chr 7:57,593,342...57,607,489

caspase 8

NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829

caspase 9

NCBI chr20:116,772,819...116,798,402
Ensembl chr20:116,772,155...116,798,930

catalase

NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592

CCN2

cellular communication network factor 2

17 beta-estradiol

NCBI chr13:41,613,838...41,617,010
Ensembl chr13:41,613,798...41,617,651

cyclin A2

NCBI chr 7:69,092,410...69,100,191
Ensembl chr 7:69,093,543...69,099,497

cyclin D1

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

cyclin D2

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

cyclin E1

NCBI chr 6:24,879,923...24,888,985

CD36

CD36 molecule (CD36 blood group)

NCBI chr21:68,214,875...68,309,336
Ensembl chr21:68,216,201...68,268,669

CD38 molecule

NCBI chr27:34,375,859...34,449,131
Ensembl chr27:34,376,271...34,449,425

CD4 molecule

NCBI chr11:6,824,797...6,856,440
Ensembl chr11:6,825,245...6,853,852

CDK2

cyclin dependent kinase 2

NCBI chr11:51,905,085...51,910,209
Ensembl chr11:51,905,115...51,909,907

CDKN1B

cyclin dependent kinase inhibitor 1B

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

collagen type I alpha 1 chain

NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930

C-reactive protein

NCBI chr20:4,232,262...4,235,826
Ensembl chr20:4,232,913...4,235,377

crystallin alpha B

NCBI chr 1:103,258,715...103,263,274
Ensembl chr 1:103,257,347...103,261,990

cystatin C

NCBI chr 2:52,834,497...52,838,785
Ensembl chr 2:52,832,181...52,838,865

CTNNB1

catenin beta 1

involved_in

PMID:22252247

GO_REF:0000107 RGD:10045362

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

CXCL1

C-X-C motif chemokine ligand 1

NCBI chr 7:22,327,041...22,329,405
Ensembl chr 7:22,569,355...22,569,900
Ensembl chr 7:22,569,355...22,569,900

CYP19A1

cytochrome P450 family 19 subfamily A member 1

involved_in

PMID:21115103

GO_REF:0000118 RGD:4890040

NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277

CYP1A2

cytochrome P450 family 1 subfamily A member 2

NCBI chr26:8,727,996...8,733,254

cytochrome P450 family 1 subfamily B member 1

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

CYP3A5

cytochrome P450 family 3 subfamily A member 5

NCBI chr28:13,473,649...13,517,905
Ensembl chr28:13,491,483...13,519,507

DBH

dopamine beta-hydroxylase

NCBI chr12:4,474,041...4,498,942
Ensembl chr12:4,474,958...4,498,910

DHH

desert hedgehog signaling molecule

NCBI chr11:45,330,593...45,336,958

DNA methyltransferase 1

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

DNMT3A

DNA methyltransferase 3 alpha

NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819

DNA methyltransferase 3 beta

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

dopamine receptor D1

NCBI chr23:77,587,340...77,591,434

dopamine receptor D2

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dual specificity phosphatase 1

NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532

EEF2

eukaryotic translation elongation factor 2

NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826

epidermal growth factor receptor

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

endonuclease G

NCBI chr12:9,322,828...9,326,833
Ensembl chr12:9,322,892...9,326,549

enolase 2

NCBI chr11:6,945,243...6,954,959
Ensembl chr11:6,945,413...6,957,304

ERBB receptor feedback inhibitor 1

acts_upstream_of_or_within

(PMID:20018910)

PMID:20018910

NCBI chr20:123,738,971...123,753,575
Ensembl chr20:123,738,973...123,755,809

estrogen receptor 1

involved_in

PMID:9528993 PMID:15304487

(PMID:15304487)

RGD
BHF-UCL

RGD:2313676

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

estrogen receptor 2

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

ESRRA

estrogen related receptor alpha

NCBI chr 1:9,918,741...9,929,481
Ensembl chr 1:9,917,436...9,929,450

ETS1

ETS proto-oncogene 1, transcription factor

NCBI chr 1:119,588,476...119,736,623
Ensembl chr 1:119,588,448...119,652,299

EZH2

enhancer of zeste 2 polycomb repressive complex 2 subunit

NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573

coagulation factor III, tissue factor

NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408

coagulation factor VII

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

FCGR1A

Fc fragment of IgG receptor Ia

fibrinogen alpha chain

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

FGF10

fibroblast growth factor 10

NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432

FLT1

fms related receptor tyrosine kinase 1

NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967

FOS like 2, AP-1 transcription factor subunit

NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373

FOXA1

forkhead box A1

involved_in

GO_REF:0000107

NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094

forkhead box J1

NCBI chr16:45,536,973...45,544,331
Ensembl chr16:45,539,510...45,544,299

GC vitamin D binding protein

NCBI chr 7:20,254,604...20,298,384
Ensembl chr 7:20,253,879...20,298,265

GHR

growth hormone receptor

involved_in

(PMID:12552091)

PMID:12552091

NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666

GHSR

growth hormone secretagogue receptor

NCBI chr15:17,008,185...17,013,504
Ensembl chr15:17,009,369...17,012,618

GJA1

gap junction protein alpha 1

NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339

GJB2

gap junction protein beta 2

NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059

GPI

glucose-6-phosphate isomerase

NCBI chr 6:29,404,067...29,451,290
Ensembl chr 6:29,403,500...29,453,162

glutathione peroxidase 1

NCBI chr22:10,754,976...10,756,617

GPX4

glutathione peroxidase 4

NCBI chr 6:873,867...876,225

glutamate ionotropic receptor AMPA type subunit 1

NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849

granulin precursor

NCBI chr16:62,037,344...62,045,765
Ensembl chr16:62,036,412...62,045,614

GSK3B

glycogen synthase kinase 3 beta

NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239

GSTP1

glutathione S-transferase pi 1

NCBI chr 1:6,676,897...6,679,936

hypoxia inducible factor 1 subunit alpha

2-methoxyestradiol

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

HMBS

hydroxymethylbilane synthase

17alpha-ethinyl estradiol

PMID:10416826

RGD:4144786

NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095

HNRNPD

heterogeneous nuclear ribonucleoprotein D

NCBI chr 7:30,729,697...30,749,793
Ensembl chr 7:30,731,175...30,749,876

HPGD

15-hydroxyprostaglandin dehydrogenase

NCBI chr 7:120,589,646...120,620,864
Ensembl chr 7:120,588,462...120,621,016

HSD17B7

hydroxysteroid 17-beta dehydrogenase 7

NCBI chr20:1,271,259...1,289,232
Ensembl chr20:1,273,052...1,288,930

heat shock transcription factor 1

NCBI chr 8:138,503,836...138,529,562
Ensembl chr 8:138,503,831...138,529,165

HSPA8

heat shock protein family A (Hsp70) member 8

NCBI chr 1:114,447,348...114,452,693
Ensembl chr 1:114,446,544...114,451,562

HTR5A

5-hydroxytryptamine receptor 5A

NCBI chr21:123,229,239...123,244,360
Ensembl chr21:123,229,816...123,241,481

HTR6

5-hydroxytryptamine receptor 6

NCBI chr20:112,873,132...112,887,533
Ensembl chr20:112,874,734...112,887,066

IFI27

interferon alpha inducible protein 27

NCBI chr24:71,884,130...71,890,813

insulin like growth factor 1

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

IGF2

insulin like growth factor 2

NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388

insulin like growth factor binding protein 2

NCBI chr10:102,469,611...102,503,229
Ensembl chr10:102,469,669...102,503,276

IHH

Indian hedgehog signaling molecule

NCBI chr10:104,960,296...104,966,596
Ensembl chr10:104,960,120...104,966,585

IL1B

interleukin 1 beta

PMID:17678971 PMID:23194835

RGD:1626644 RGD:7175531

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

INSIG1

insulin induced gene 1

NCBI chr21:123,448,614...123,460,778
Ensembl chr21:123,449,106...123,460,807

insulin receptor

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

ITGAM

integrin subunit alpha M

NCBI chr 5:27,957,162...28,042,697
Ensembl chr 5:27,957,324...28,042,691

potassium inwardly rectifying channel subfamily J member 11

NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801

LDLR

low density lipoprotein receptor

PMID:3559401 PMID:19008317

RGD:2317989 RGD:2324634

NCBI chr 6:10,062,204...10,091,780
Ensembl chr 6:10,062,790...10,091,377

leptin

NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220

LOC103219825

protein patched homolog 1

NCBI chr12:107,580,895...107,656,443
Ensembl chr12:107,590,663...107,652,985

LOC103223058

glutathione hydrolase light chain 2

NCBI chr19:7,353,922...7,406,392

LOC103223672

low affinity immunoglobulin gamma Fc region receptor II-b

NCBI chr20:2,398,425...2,413,328

mucin-4

NCBI chr15:91,313,060...91,345,172

LOC103243413

signal transducer and activator of transcription 5B

involved_in

(PMID:12552091)

PMID:12552091

NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445

MAP1B

microtubule associated protein 1B

NCBI chr 4:66,445,687...66,548,595
Ensembl chr 4:66,445,901...66,549,142

MAP2

microtubule associated protein 2

NCBI chr10:95,319,649...95,431,106
Ensembl chr10:95,349,157...95,431,320

mitogen-activated protein kinase 1

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

MAPK15

mitogen-activated protein kinase 15

NCBI chr 8:137,932,291...137,938,392
Ensembl chr 8:137,932,364...137,938,626

MBD1

methyl-CpG binding domain protein 1

NCBI chr18:30,675,419...30,690,111
Ensembl chr18:30,675,653...30,685,946

MBD2

methyl-CpG binding domain protein 2

NCBI chr18:26,714,610...26,785,028

MBD3

methyl-CpG binding domain protein 3

NCBI chr 6:1,357,388...1,371,835
Ensembl chr 6:1,357,204...1,371,777

MBD4

methyl-CpG binding domain 4, DNA glycosylase

NCBI chr22:51,616,840...51,626,232
Ensembl chr22:51,616,803...51,626,224

methyl-CpG binding protein 2

NCBI chr X:128,445,028...128,519,892
Ensembl chr X:128,453,577...128,455,785

macrophage migration inhibitory factor

NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757

MMP15

matrix metallopeptidase 15

NCBI chr 5:43,961,288...43,982,182
Ensembl chr 5:43,960,891...43,982,261

MMP3

matrix metallopeptidase 3

NCBI chr 1:94,216,156...94,224,437
Ensembl chr 1:94,216,173...94,224,264

MMP9

matrix metallopeptidase 9

NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712

MYC proto-oncogene, bHLH transcription factor

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

NCOA1

nuclear receptor coactivator 1

PMID:9564863 PMID:9808623

RGD:2293532 RGD:2306464

NCBI chr14:82,898,368...83,028,137
Ensembl chr14:82,897,348...83,013,589

NCOA2

nuclear receptor coactivator 2

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

NCOR2

nuclear receptor corepressor 2

NCBI chr11:119,675,363...119,917,059
Ensembl chr11:119,676,345...119,917,000

NK2 homeobox 5

NCBI chr23:75,391,833...75,399,003
Ensembl chr23:75,391,847...75,395,205

nitric oxide synthase 2

NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257

nitric oxide synthase 3

PMID:18004295 PMID:20233295 PMID:21292265

RGD:2292118 RGD:4892005 RGD:7777127

NCBI chr21:119,174,829...119,196,840

NPY1R

neuropeptide Y receptor Y1

NCBI chr 7:109,774,700...109,794,543
Ensembl chr 7:109,774,918...109,776,905

NQO1

NAD(P)H quinone dehydrogenase 1

NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599

NR2F2

nuclear receptor subfamily 2 group F member 2

NCBI chr29:14,889,526...14,901,848
Ensembl chr29:14,891,737...14,903,813

NRF1

nuclear respiratory factor 1

NCBI chr21:98,227,088...98,377,095
Ensembl chr21:98,268,395...98,377,096

neurotrimin

NCBI chr 1:122,405,280...123,378,287
Ensembl chr 1:123,182,630...123,379,429

neurotensin

NCBI chr11:81,270,147...81,278,327
Ensembl chr11:81,270,593...81,277,713

OGG1

8-oxoguanine DNA glycosylase

NCBI chr22:45,757,414...45,763,690

oxytocin/neurophysin I prepropeptide

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

oxytocin receptor

NCBI chr22:44,746,108...44,764,501
Ensembl chr22:44,742,419...44,763,243

PAM

peptidylglycine alpha-amidating monooxygenase

NCBI chr23:6,316,428...6,482,959
Ensembl chr23:6,316,428...6,486,751

PAWR

pro-apoptotic WT1 regulator

NCBI chr11:75,132,547...75,219,633
Ensembl chr11:75,133,186...75,219,072

PCNA

proliferating cell nuclear antigen

NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991

PDGFA

platelet derived growth factor subunit A

NCBI chr28:21,044,549...21,068,411
Ensembl chr28:21,047,219...21,069,827

PDGFB

platelet derived growth factor subunit B

NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395

PDGFRA

platelet derived growth factor receptor alpha

NCBI chr 7:14,243,291...14,307,373
Ensembl chr 7:14,241,070...14,307,422

PDGFRB

platelet derived growth factor receptor beta

NCBI chr23:52,724,061...52,766,264
Ensembl chr23:52,724,005...52,766,234

proenkephalin

NCBI chr 8:52,458,113...52,463,933
Ensembl chr 8:52,457,904...52,463,859

phosphoinositide-3-kinase regulatory subunit 1

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

periostin

NCBI chr 3:16,060,013...16,095,867
Ensembl chr 3:16,059,965...16,095,791

protein phosphatase 1 regulatory subunit 9B

NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680

PR/SET domain 2

NCBI chr20:118,437,171...118,565,554
Ensembl chr20:118,436,717...118,550,461

PRKCA

protein kinase C alpha

NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256

PRL

prolactin

PMID:17122082 PMID:28710248

RGD:1642579 RGD:401960105

NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631

PTEN

phosphatase and tensin homolog

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

PTGER3

prostaglandin E receptor 3

NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959

PTGFR

prostaglandin F receptor

involved_in

GO_REF:0000107

NCBI chr20:54,660,329...54,706,212
Ensembl chr20:54,659,197...54,704,452

PTGIS

prostaglandin I2 synthase

NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264

prostaglandin-endoperoxide synthase 2

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

PTK2

protein tyrosine kinase 2

NCBI chr 8:134,897,511...135,246,300

pleiotrophin

NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215

RAMP2

receptor activity modifying protein 2

NCBI chr16:63,526,915...63,529,697
Ensembl chr16:63,526,305...63,528,767

RARA

retinoic acid receptor alpha

NCBI chr16:65,817,849...65,866,862
Ensembl chr16:65,817,757...65,866,878

RBBP8

RB binding protein 8, endonuclease

NCBI chr18:57,501,070...57,617,301
Ensembl chr18:57,501,271...57,597,670

RGS9

regulator of G protein signaling 9

NCBI chr16:56,199,051...56,291,002
Ensembl chr16:56,199,343...56,288,290

RNF4

ring finger protein 4

NCBI chr27:46,245,786...46,290,671

ryanodine receptor 1

NCBI chr 6:33,080,443...33,234,478
Ensembl chr 6:33,080,758...33,213,788

SCP2

sterol carrier protein 2

NCBI chr20:79,868,825...79,993,906
Ensembl chr20:79,865,332...79,993,835

SERPINA1

serpin family A member 1

NCBI chr24:72,158,521...72,171,139
Ensembl chr24:72,156,784...72,163,500

SFRP4

secreted frizzled related protein 4

NCBI chr21:20,601,281...20,611,273
Ensembl chr21:20,601,396...20,612,138

SHH

sonic hedgehog signaling molecule

NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395

SLC34A1

solute carrier family 34 member 1

NCBI chr23:79,395,923...79,410,835
Ensembl chr23:79,396,250...79,411,695

SLC34A2

solute carrier family 34 member 2

NCBI chr27:24,674,419...24,698,844
Ensembl chr27:24,674,584...24,690,984

solute carrier family 6 member 1

NCBI chr22:47,033,436...47,076,785
Ensembl chr22:47,033,467...47,078,844

SLC6A4

solute carrier family 6 member 4

NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616

SOCS1

suppressor of cytokine signaling 1

NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991

SOCS2

suppressor of cytokine signaling 2

involved_in

GO_REF:0000107

NCBI chr11:88,964,805...88,971,147
Ensembl chr11:88,966,940...88,971,515

suppressor of cytokine signaling 3

NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423

SPRR2G

small proline rich protein 2G

acts_upstream_of_or_within

(PMID:15232223)

PMID:15232223

NCBI chr20:10,602,861...10,617,406
Ensembl chr20:10,616,875...10,617,093

steroid 5 alpha-reductase 1

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

STAT3

signal transducer and activator of transcription 3

involved_in

PMID:17916759

GO_REF:0000107 RGD:2291922

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

STXBP1

syntaxin binding protein 1

NCBI chr12:10,440,061...10,519,798
Ensembl chr12:10,439,801...10,519,777

TACR1

tachykinin receptor 1

NCBI chr14:32,080,319...32,236,556
Ensembl chr14:32,083,615...32,233,596

TACR3

tachykinin receptor 3

PMID:10342838 PMID:12390879

RGD:2305937 RGD:5147482

NCBI chr 7:51,662,248...51,764,058
Ensembl chr 7:51,665,147...51,762,390

TFPI

tissue factor pathway inhibitor

NCBI chr10:73,004,762...73,105,772
Ensembl chr10:73,002,522...73,105,858

transforming growth factor beta 1

involved_in

PMID:15746252

GO_REF:0000107 RGD:2302102

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

TGFB2

transforming growth factor beta 2

NCBI chr25:11,163,651...11,259,868
Ensembl chr25:11,163,100...11,258,470

tyrosine hydroxylase

NCBI chr 1:1,969,194...1,977,263
Ensembl chr 1:1,966,460...1,977,218

TXNIP

thioredoxin interacting protein

NCBI chr20:12,756,145...12,759,853
Ensembl chr20:12,756,053...12,761,177

urocortin

NCBI chr14:80,303,210...80,304,910
Ensembl chr14:80,304,416...80,304,790

UROD

uroporphyrinogen decarboxylase

NCBI chr20:87,772,685...87,776,110
Ensembl chr20:87,772,261...87,775,978

vitamin D receptor

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

vascular endothelial growth factor A

NCBI chr17:28,377,959...28,394,508

vimentin

NCBI chr 9:17,183,466...17,191,771
Ensembl chr 9:17,183,388...17,191,829

WFDC1

WAP four-disulfide core domain 1

NCBI chr 5:69,700,984...69,734,682
Ensembl chr 5:69,701,470...69,731,823

Wnt family member 4

NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203

Wnt family member 5A

NCBI chr22:16,809,454...16,836,815
Ensembl chr22:16,809,451...16,825,048

Wnt family member 7A

NCBI chr22:49,805,415...49,863,115
Ensembl chr22:49,805,463...49,862,830

response to exogenous dsRNA

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CARD9

caspase recruitment domain family member 9

acts_upstream_of_or_within

(PMID:17187069)

PMID:17187069

NCBI chr12:1,829,913...1,841,489
Ensembl chr12:1,832,989...1,837,914

DDX1

DEAD-box helicase 1

acts_upstream_of_or_within

(PMID:21703541)

NCBI chr14:92,007,446...92,045,414
Ensembl chr14:92,007,036...92,045,190

DDX21

DExD-box helicase 21

acts_upstream_of_or_within

(PMID:21703541)

NCBI chr 9:62,339,614...62,370,032

DHX36

DEAH-box helicase 36

acts_upstream_of_or_within

(PMID:21703541)

NCBI chr15:36,387,242...36,438,133
Ensembl chr15:36,387,228...36,437,606

EIF2AK2

eukaryotic translation initiation factor 2 alpha kinase 2

NCBI chr14:70,246,081...70,290,851
Ensembl chr14:70,247,168...70,296,463

IRAK3

interleukin 1 receptor associated kinase 3

involved_in

GO_REF:0000107

NCBI chr11:61,868,817...61,920,896
Ensembl chr11:61,869,173...61,920,406

IRF3

interferon regulatory factor 3

acts_upstream_of_or_within

(PMID:12855817), (PMID:12872135)

PMID:12855817 PMID:12872135

NCBI chr 6:42,835,285...42,841,487
Ensembl chr 6:42,831,203...42,840,796

KCNJ8

potassium inwardly rectifying channel subfamily J member 8

involved_in
acts_upstream_of_or_within

(PMID:18026101)

PMID:18026101

GO_REF:0000107

NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042

mitogen-activated protein kinase 1

involved_in
acts_upstream_of_or_within

(PMID:12872135)

GO_REF:0000107

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

MAPK3

mitogen-activated protein kinase 3

involved_in
acts_upstream_of_or_within

(PMID:12872135)

GO_REF:0000107

NCBI chr 5:26,536,471...26,545,666
Ensembl chr 5:26,536,532...26,546,461

NFKBIA

NFKB inhibitor alpha

involved_in
acts_upstream_of_or_within

(PMID:12872135)

GO_REF:0000107

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

NOD2

nucleotide binding oligomerization domain containing 2

acts_upstream_of_or_within

(PMID:15692051)

PMID:15692051

NCBI chr 5:36,492,158...36,531,766
Ensembl chr 5:36,496,414...36,530,499

RFTN1

raftlin, lipid raft linker 1

acts_upstream_of_or_within

(PMID:21266579)

PMID:21266579

NCBI chr15:61,159,573...61,290,342
Ensembl chr15:61,159,930...61,289,965

RFTN2

raftlin family member 2

involved_in
acts_upstream_of_or_within

(PMID:21266579)

PMID:21266579

GO_REF:0000107

NCBI chr10:83,082,681...83,168,828
Ensembl chr10:83,079,215...83,168,814

RIGI

RNA sensor RIG-I

acts_upstream_of_or_within

(PMID:21703541)

NCBI chr12:47,729,040...47,800,995
Ensembl chr12:47,729,076...47,799,570

RIPK2

receptor interacting serine/threonine kinase 2

involved_in
acts_upstream_of_or_within

(PMID:11894098)

PMID:11894098

GO_REF:0000107

NCBI chr 8:84,843,391...84,881,087
Ensembl chr 8:84,843,471...84,881,303

SLC3A2

solute carrier family 3 member 2

acts_upstream_of_or_within

(PMID:21266579)

PMID:21266579

NCBI chr 1:11,011,351...11,050,494
Ensembl chr 1:11,008,120...11,050,298

signal transducer and activator of transcription 1

acts_upstream_of_or_within

(PMID:12872135)

NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393

TICAM1

toll like receptor adaptor molecule 1

acts_upstream_of_or_within
involved_in

PMID:12855817 PMID:12872135 PMID:21266579 PMID:21703541

(PMID:21266579)
(PMID:21703541)
(PMID:12872135)
(PMID:12855817)

MGI
TreeGrafter
UniProt

GO_REF:0000104 GO_REF:0000118

NCBI chr 6:4,526,719...4,543,251
Ensembl chr 6:4,527,033...4,529,168

TICAM2

toll like receptor adaptor molecule 2

involved_in

GO_REF:0000118

NCBI chr23:18,831,361...18,855,476
Ensembl chr23:18,833,262...18,833,969

TLR3

toll like receptor 3

acts_upstream_of_or_within
involved_in

(PMID:21266579)
(PMID:12855817)

PMID:12855817 PMID:21266579

GO_REF:0000107

NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232

response to fenofibrate

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCB4

ATP binding cassette subfamily B member 4

involved_in

(MGI:79581|PMID:8615769)

PMID:8615769

MGI:79581

NCBI chr21:61,459,344...61,529,017

uncoupling protein 3

NCBI chr 1:65,269,611...65,279,079
Ensembl chr 1:65,269,607...65,278,807

response to folic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily G member 2 (JR blood group)

NCBI chr 7:36,458,110...36,599,753

ASCL1

achaete-scute family bHLH transcription factor 1

NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506

BCHE

butyrylcholinesterase

NCBI chr15:23,708,121...23,778,027
Ensembl chr15:23,708,155...23,778,286

BCL2 apoptosis regulator

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

EEF2

eukaryotic translation elongation factor 2

NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826

glutathione peroxidase 1

NCBI chr22:10,754,976...10,756,617

gelsolin

NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938

HSPA9

heat shock protein family A (Hsp70) member 9

NCBI chr23:41,230,675...41,251,177
Ensembl chr23:41,231,364...41,251,150

LOC103221104

cystathionine beta-synthase

involved_in
acts_upstream_of_or_within

(PMID:10993757)

PMID:10993757

GO_REF:0000107

NCBI chr 2:86,905,104...86,933,780

LRP6

LDL receptor related protein 6

acts_upstream_of_or_within

(PMID:17050573)

PMID:17050573

NCBI chr11:12,016,542...12,170,496
Ensembl chr11:12,021,560...12,170,663

MGMT

O-6-methylguanine-DNA methyltransferase

NCBI chr 9:122,089,768...122,376,320

MOG

myelin oligodendrocyte glycoprotein

NCBI chr17:42,947,174...42,963,046
Ensembl chr17:42,947,279...42,962,159

MTHFR

methylenetetrahydrofolate reductase

NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950

NFKBIZ

NFKB inhibitor zeta

involved_in

GO_REF:0000107

NCBI chr22:79,044,624...79,077,736
Ensembl chr22:79,044,619...79,055,776

NRF1

nuclear respiratory factor 1

NCBI chr21:98,227,088...98,377,095
Ensembl chr21:98,268,395...98,377,096

OGG1

8-oxoguanine DNA glycosylase

NCBI chr22:45,757,414...45,763,690

TIMP3

TIMP metallopeptidase inhibitor 3

NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449

thymidylate synthetase

NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856

vascular endothelial growth factor A

NCBI chr17:28,377,959...28,394,508

ZNF354A

zinc finger protein 354A

NCBI chr23:80,407,134...80,425,920
Ensembl chr23:80,407,085...80,423,055

response to forskolin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HRH3

histamine receptor H3

NCBI chr 2:2,019,878...2,025,218
Ensembl chr 2:2,020,286...2,025,202

response to genistein

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGER

advanced glycosylation end-product specific receptor

NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127

BRCA1 DNA repair associated

NCBI chr16:63,162,827...63,243,928

cytochrome P450 family 11 subfamily A member 1

NCBI chr26:9,122,008...9,151,844

cytochrome P450 family 1 subfamily A member 1

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

estrogen receptor 2

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

coagulation factor VII

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

FGA

fibrinogen alpha chain

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

PDIA3

protein disulfide isomerase family A member 3

NCBI chr26:39,273,982...39,300,170
Ensembl chr26:39,272,997...39,349,966

response to glucocorticoid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCB4

ATP binding cassette subfamily B member 4

NCBI chr21:61,459,344...61,529,017

ACADM

acyl-CoA dehydrogenase medium chain

NCBI chr20:57,428,863...57,468,422
Ensembl chr20:57,428,472...57,468,359

ACADS

acyl-CoA dehydrogenase short chain

NCBI chr11:116,083,156...116,096,554
Ensembl chr11:116,083,276...116,096,607

ACSBG1

acyl-CoA synthetase bubblegum family member 1

involved_in
acts_upstream_of_or_within

(PMID:19167491)

PMID:19167491

GO_REF:0000107

NCBI chr26:5,117,740...5,183,164
Ensembl chr26:5,117,818...5,185,418

ADAM9

ADAM metallopeptidase domain 9

involved_in

(MGI:3828402|PMID:16311053)

PMID:16311053

MGI:3828402

NCBI chr 8:37,017,827...37,131,462
Ensembl chr 8:37,017,545...37,131,615

ADIPOQ

adiponectin, C1Q and collagen domain containing

NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391

adrenomedullin

NCBI chr 1:54,518,359...54,520,683
Ensembl chr 1:54,518,358...54,520,686

AGL

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

NCBI chr20:33,422,807...33,491,335
Ensembl chr20:33,422,790...33,490,016

AGXT

alanine--glyoxylate and serine--pyruvate aminotransferase

NCBI chr10:126,933,711...126,943,980
Ensembl chr10:126,933,835...126,944,354

AIF1

allograft inflammatory factor 1

dexamethasone

aminolevulinate dehydratase

prednisolone; in resistance exercised rats

PMID:12596873

RGD:4144180

NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845

ALDH3A1

aldehyde dehydrogenase 3 family member A1

NCBI chr16:18,302,145...18,312,768
Ensembl chr16:18,302,142...18,312,756

ALDOB

aldolase, fructose-bisphosphate B

NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258

alkaline phosphatase, biomineralization associated

NCBI chr20:111,055,583...111,124,143
Ensembl chr20:111,055,558...111,081,850

annexin A1

NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562

annexin A3

NCBI chr 7:26,999,136...27,060,783
Ensembl chr 7:26,999,012...27,061,692

apolipoprotein A2

NCBI chr20:2,757,939...2,760,356
Ensembl chr20:2,759,237...2,760,686

aquaporin 4

NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156

amphiregulin

NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162

argininosuccinate synthase 1

NCBI chr12:7,643,484...7,701,334

BCL2 associated agonist of cell death

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

BCHE

butyrylcholinesterase

NCBI chr15:23,708,121...23,778,027
Ensembl chr15:23,708,155...23,778,286

BCKDHA

branched chain keto acid dehydrogenase E1 subunit alpha

NCBI chr 6:35,717,679...35,747,245
Ensembl chr 6:35,717,694...35,751,098

BCKDHB

branched chain keto acid dehydrogenase E1 subunit beta

NCBI chr13:4,845,481...5,087,558
Ensembl chr13:4,845,457...5,087,745

BCL2 apoptosis regulator

acts_upstream_of_or_within

(PMID:8372353)
(PMID:8313913)

PMID:8313913 PMID:8372353

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

bone gamma-carboxyglutamate protein

dexamethasone

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

BIRC5

baculoviral IAP repeat containing 5

NCBI chr16:70,226,824...70,237,000

bone morphogenetic protein 4

NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225

BMP6

bone morphogenetic protein 6

NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382

C1QB

complement C1q B chain

NCBI chr20:110,003,036...110,011,317
Ensembl chr20:110,002,864...110,011,316

complement C3

NCBI chr 6:6,250,422...6,289,264

CALCR

calcitonin receptor

involved_in

(PMID:11250927)

PMID:11250927

NCBI chr21:55,433,438...55,585,608
Ensembl chr21:55,523,412...55,583,735

caspase 3

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

caveolin 1

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

CCKAR

cholecystokinin A receptor

NCBI chr27:23,855,766...23,866,104
Ensembl chr27:23,856,705...23,865,367

CCL1

C-C motif chemokine ligand 1

NCBI chr16:27,868,925...27,890,143

C-C motif chemokine ligand 2

NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416

C-C motif chemokine ligand 5

NCBI chr16:29,351,214...29,361,317

cyclin D1

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

cyclin dependent kinase inhibitor 1A

NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342

CDO1

cysteine dioxygenase type 1

NCBI chr23:19,049,612...19,061,783
Ensembl chr23:19,049,262...19,061,740

CPN1

carboxypeptidase N subunit 1

NCBI chr 9:93,077,181...93,121,339
Ensembl chr 9:93,077,127...93,121,059

carbamoyl-phosphate synthase 1

PMID:8985169 PMID:17397987

RGD:2303516 RGD:2303518

NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206

cathepsin L

dexamethasone

NCBI chr12:98,347,770...98,353,426
Ensembl chr12:98,347,800...98,353,467

CXCL1

C-X-C motif chemokine ligand 1

NCBI chr 7:22,327,041...22,329,405
Ensembl chr 7:22,569,355...22,569,900
Ensembl chr 7:22,569,355...22,569,900

DPYD

dihydropyrimidine dehydrogenase

NCBI chr20:35,376,738...36,215,388
Ensembl chr20:35,377,266...36,215,679

dual specificity phosphatase 1

NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532

FABP4

fatty acid binding protein 4

NCBI chr 8:76,895,516...76,900,153
Ensembl chr 8:76,894,512...76,900,212

FKRP

fukutin related protein

involved_in
acts_upstream_of_or_within

(PMID:27109613)

PMID:27109613

GO_REF:0000107

NCBI chr 6:40,100,399...40,128,340
Ensembl chr 6:40,126,321...40,127,808

fibronectin 1

NCBI chr10:101,177,867...101,254,613
Ensembl chr10:101,176,789...101,254,633

FOS like 2, AP-1 transcription factor subunit

involved_in
acts_upstream_of_or_within

(PMID:30233597)

PMID:30233597

GO_REF:0000107

NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373

GHR

growth hormone receptor

NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666

GHRHR

growth hormone releasing hormone receptor

involved_in

(PMID:9482665)

PMID:9482665

NCBI chr21:27,402,765...27,417,536
Ensembl chr21:27,404,886...27,417,521

GOT1

glutamic-oxaloacetic transaminase 1

involved_in

GO_REF:0000107

NCBI chr 9:92,463,017...92,489,227
Ensembl chr 9:92,462,782...92,488,310

GPR83

G protein-coupled receptor 83

involved_in
acts_upstream_of_or_within

(PMID:1663214)

PMID:1663214

GO_REF:0000107

NCBI chr 1:85,577,620...85,597,780
Ensembl chr 1:85,583,039...85,597,423

hypoxia inducible factor 1 subunit alpha

prednisolone

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

HMGB1

high mobility group box 1

acts_upstream_of_or_within

(PMID:10391216)

PMID:10391216

NCBI chr 3:9,353,333...9,357,765

3-hydroxy-3-methylglutaryl-CoA synthase 2

dexamethasone

NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016

HNMT

histamine N-methyltransferase

NCBI chr10:22,188,151...22,238,665
Ensembl chr10:22,188,110...22,238,671

HSD11B2

hydroxysteroid 11-beta dehydrogenase 2

NCBI chr 5:60,017,967...60,040,959
Ensembl chr 5:60,019,434...60,025,353

heat shock protein family D (Hsp60) member 1

NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363

insulin like growth factor 1

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

insulin like growth factor binding protein 2

NCBI chr10:102,469,611...102,503,229
Ensembl chr10:102,469,669...102,503,276

IL10

interleukin 10

involved_in

PMID:16827395

GO_REF:0000107 RGD:1598633

NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836

interleukin 1 beta

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

IL1RN

interleukin 1 receptor antagonist

involved_in

(PMID:10443688)

PMID:10443688

NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326

interleukin 22

NCBI chr11:63,881,743...63,887,695
Ensembl chr11:63,882,093...63,886,761

IL6

interleukin 6

involved_in

GO_REF:0000107

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

IL6R

interleukin 6 receptor

NCBI chr20:9,345,723...9,418,963
Ensembl chr20:9,361,152...9,396,610

insulin receptor

Dexamethasone

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

KCNJ10

potassium inwardly rectifying channel subfamily J member 10

NCBI chr20:3,873,915...3,907,587
Ensembl chr20:3,902,513...3,903,652

KRAS

KRAS proto-oncogene, GTPase

PMID:1420288 PMID:16543373

RGD:1581767 RGD:1581770

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

LCAT

lecithin-cholesterol acyltransferase

NCBI chr 5:59,495,936...59,500,530
Ensembl chr 5:59,497,115...59,500,448

LIPC

lipase C, hepatic type

dexamethasone

NCBI chr26:24,946,843...25,109,338
Ensembl chr26:24,946,673...25,087,921

LOC103214902

sodium/hydrogen exchanger 3

NCBI chr 4:362,417...408,113
Ensembl chr 4:365,135...408,033

LOC103216568

pancreatic lipase-related protein 2

NCBI chr 9:109,428,235...109,453,687

LOC103226816

ATP-binding cassette sub-family A member 3

NCBI chr 5:2,171,487...2,218,851

MAP2K1

mitogen-activated protein kinase kinase 1

NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782

midkine

NCBI chr 1:18,945,355...18,948,394
Ensembl chr 1:18,946,378...18,947,134

matrix Gla protein

NCBI chr11:14,776,668...14,780,796
Ensembl chr11:14,776,209...14,780,947

macrophage migration inhibitory factor

NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757

myostatin

NCBI chr10:75,564,816...75,570,956
Ensembl chr10:75,565,152...75,570,528

nerve growth factor

NCBI chr20:18,361,795...18,413,987
Ensembl chr20:18,413,108...18,413,833

oxytocin/neurophysin I prepropeptide

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

PAM

peptidylglycine alpha-amidating monooxygenase

NCBI chr23:6,316,428...6,482,959
Ensembl chr23:6,316,428...6,486,751

PCSK1

proprotein convertase subtilisin/kexin type 1

dexamethasone

NCBI chr 4:90,246,413...90,289,148
Ensembl chr 4:90,248,598...90,289,089

PDCD7

programmed cell death 7

involved_in

(MGI:1333591|PMID:10037816)

HGNC-UCL

PMID:10037816

MGI:1333591

NCBI chr26:18,457,101...18,470,020
Ensembl chr26:18,457,166...18,469,525

PDX1

pancreatic and duodenal homeobox 1

dexamethasone

NCBI chr 3:7,038,088...7,046,593
Ensembl chr 3:7,041,466...7,045,976

PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

PMID:7593243 PMID:8131849

RGD:2302678 RGD:2302680

NCBI chr X:51,015,810...51,077,444
Ensembl chr X:51,016,318...51,071,977

phosphoinositide-3-kinase regulatory subunit 1

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

PLA2G4A

phospholipase A2 group IVA

NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431

PNLIPRP1

pancreatic lipase related protein 1

NCBI chr 9:109,397,970...109,417,422
Ensembl chr 9:109,399,227...109,417,351

PPARGC1B

PPARG coactivator 1 beta

NCBI chr23:52,337,802...52,462,553
Ensembl chr23:52,428,052...52,455,089

PTGDS

prostaglandin D2 synthase

NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531

prostaglandin-endoperoxide synthase 2

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

PTPRU

protein tyrosine phosphatase receptor type U

NCBI chr20:103,497,681...103,586,494
Ensembl chr20:103,498,839...103,586,348

RHOA

ras homolog family member A

NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704

ribosomal protein S6 kinase B1

NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453

retinoid X receptor alpha

PMID:17483744 PMID:19008781

RGD:1643106 RGD:2317466

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

S100B

S100 calcium binding protein B

NCBI chr 2:90,188,820...90,194,986
Ensembl chr 2:90,188,639...90,195,023

SCGB1A1

secretoglobin family 1A member 1

NCBI chr 1:11,470,091...11,474,915
Ensembl chr 1:11,470,195...11,474,149

syndecan 1

NCBI chr14:87,499,732...87,523,122
Ensembl chr14:87,499,574...87,525,026

SFRP4

secreted frizzled related protein 4

NCBI chr21:20,601,281...20,611,273
Ensembl chr21:20,601,396...20,612,138

surfactant protein B

NCBI chr14:21,487,424...21,497,491
Ensembl chr14:21,488,387...21,499,850

surfactant protein C

NCBI chr 8:20,229,756...20,233,568
Ensembl chr 8:20,230,870...20,234,020

surfactant protein D

NCBI chr 9:51,809,241...51,820,974
Ensembl chr 9:51,811,052...51,820,650

SHC1

SHC adaptor protein 1

NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610

sucrase-isomaltase

NCBI chr15:24,480,060...24,582,468
Ensembl chr15:24,482,865...24,582,394

SLCO1B3

solute carrier organic anion transporter family member 1B3

NCBI chr11:20,637,429...20,760,577
Ensembl chr11:20,648,582...20,761,161

suppressor of cytokine signaling 3

NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423

SPARC

secreted protein acidic and cysteine rich

NCBI chr23:54,224,003...54,248,869
Ensembl chr23:54,222,838...54,238,006

TAT

tyrosine aminotransferase

NCBI chr 5:54,695,342...54,749,291
Ensembl chr 5:54,693,458...54,705,082

toll like receptor 4

NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515

TNF

tumor necrosis factor

involved_in

(PMID:10443688)

tryptophan hydroxylase 2

NCBI chr11:67,568,744...67,664,911

TRIM63

tripartite motif containing 63

NCBI chr20:106,676,299...106,714,394
Ensembl chr20:106,703,949...106,716,656

thymidylate synthetase

NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856

urocortin

NCBI chr14:80,303,210...80,304,910
Ensembl chr14:80,304,416...80,304,790

uncoupling protein 3

NCBI chr 1:65,269,611...65,279,079
Ensembl chr 1:65,269,607...65,278,807

Wnt family member 5A

NCBI chr22:16,809,454...16,836,815
Ensembl chr22:16,809,451...16,825,048

Wnt family member 7B

NCBI chr19:28,387,324...28,444,019
Ensembl chr19:28,385,422...28,441,350

response to histamine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CRACR2A

calcium release activated channel regulator 2A

involved_in

(PMID:31092558)

PMID:31092558

NCBI chr11:3,659,745...3,815,742
Ensembl chr11:3,667,647...3,743,026

dopamine receptor D2

involved_in

GO_REF:0000107

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

involved_in

(PMID:16839358)

PMID:16839358

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

dopamine receptor D4

involved_in

GO_REF:0000107

NCBI chr 1:454,018...459,582

response to hydroxyisoflavone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

bone gamma-carboxyglutamate protein

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

epidermal growth factor receptor

genistein

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

response to indole-3-methanol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cytochrome P450 family 1 subfamily B member 1

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

MMP1

matrix metallopeptidase 1

NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767

response to kainic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DDIT3

DNA damage inducible transcript 3

NCBI chr11:53,424,693...53,429,094
Ensembl chr11:53,424,868...53,425,576

EIF2S1

eukaryotic translation initiation factor 2 subunit alpha

NCBI chr24:44,599,017...44,623,723
Ensembl chr24:44,598,287...44,623,298

GDF10

growth differentiation factor 10

NCBI chr 9:44,066,979...44,080,319
Ensembl chr 9:44,067,469...44,079,522

IREB2

iron responsive element binding protein 2

NCBI chr26:4,842,328...4,905,941
Ensembl chr26:4,842,122...4,905,964

lipocalin 2

NCBI chr12:9,976,278...9,981,087
Ensembl chr12:9,976,614...9,980,870

protein phosphatase 1 regulatory subunit 9B

NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680

pleiotrophin

NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215

sirtuin 1

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

SLC6A12

solute carrier family 6 member 12

NCBI chr11:192,590...223,809
Ensembl chr11:192,398...215,991

response to ketamine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

hexokinase 1

NCBI chr 9:61,917,501...62,029,737
Ensembl chr 9:61,917,440...62,001,843

hippocalcin

NCBI chr20:99,974,952...99,983,194
Ensembl chr20:99,975,742...99,980,728

response to L-ascorbic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACP5

acid phosphatase 5, tartrate resistant

NCBI chr 6:10,488,572...10,493,508
Ensembl chr 6:10,488,460...10,491,519

BCL2 apoptosis regulator

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

catalase

NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592

cytochrome P450 family 11 subfamily A member 1

in PCB-treated rats

NCBI chr26:9,122,008...9,151,844

GSTP1

glutathione S-transferase pi 1

NCBI chr 1:6,676,897...6,679,936

hydroxysteroid 17-beta dehydrogenase 3

in PCB-treated rats

NCBI chr12:106,831,807...106,885,543
Ensembl chr12:106,832,034...106,886,385

interleukin 1 alpha

NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611

interleukin 1 beta

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

integrin subunit alpha 2

NCBI chr 4:49,280,289...49,382,101
Ensembl chr 4:49,317,648...49,380,051

SOD2

superoxide dismutase 2

NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974

SPARC

secreted protein acidic and cysteine rich

NCBI chr23:54,224,003...54,248,869
Ensembl chr23:54,222,838...54,238,006

VWF

von Willebrand factor

NCBI chr11:5,994,499...6,176,949
Ensembl chr11:5,994,039...6,162,260

response to methotrexate

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DHFR

dihydrofolate reductase

involved_in

GO_REF:0000043

NCBI chr 4:74,787,292...74,811,196
Ensembl chr 4:74,787,629...74,810,960

response to mineralocorticoid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CCN2

cellular communication network factor 2

aldosterone

NCBI chr13:41,613,838...41,617,010
Ensembl chr13:41,613,798...41,617,651

HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

aldosterone

NCBI chr21:32,167,126...32,178,031
Ensembl chr21:32,167,337...32,176,980

HTR1B

5-hydroxytryptamine receptor 1B

NCBI chr13:2,143,646...2,145,943
Ensembl chr13:2,144,313...2,145,485

KCNJ10

potassium inwardly rectifying channel subfamily J member 10

NCBI chr20:3,873,915...3,907,587
Ensembl chr20:3,902,513...3,903,652

KRAS

KRAS proto-oncogene, GTPase

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

neurotensin

NCBI chr11:81,270,147...81,278,327
Ensembl chr11:81,270,593...81,277,713

serine protease 8

NCBI chr 5:27,820,898...27,827,873
Ensembl chr 5:27,817,830...27,824,926

SRC proto-oncogene, non-receptor tyrosine kinase

NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776

response to morphine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADRA1B

adrenoceptor alpha 1B

acts_upstream_of_or_within

(PMID:11923452)

PMID:11923452

NCBI chr23:62,281,500...62,338,290

ADRA2A

adrenoceptor alpha 2A

NCBI chr 9:104,015,577...104,019,364
Ensembl chr 9:104,016,580...104,017,932

AGO2

argonaute RISC catalytic component 2

NCBI chr 8:134,761,651...134,855,971
Ensembl chr 8:134,767,182...134,823,070

ARC

activity regulated cytoskeleton associated protein

PMID:21549764 PMID:30550948

RGD:401851922 RGD:401959617

NCBI chr 8:136,857,402...136,860,933
Ensembl chr 8:136,859,438...136,860,628

arrestin beta 1

NCBI chr 1:66,489,358...66,580,167
Ensembl chr 1:66,490,102...66,580,154

arrestin beta 2

NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385

brain derived neurotrophic factor

NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336

dopamine receptor D2

involved_in
acts_upstream_of_or_within

(PMID:9252189)
(PMID:11567069)
(PMID:12182883)
(PMID:11264672)

PMID:9252189 PMID:11264672 PMID:11567069 PMID:12182883

GO_REF:0000107

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

dopamine receptor D3

acts_upstream_of_or_within

(PMID:12574430)

PMID:12574430

NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690

early growth response 1

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

FosB proto-oncogene, AP-1 transcription factor subunit

PMID:20438612 PMID:23185589

RGD:401851068 RGD:401900159

NCBI chr 6:38,916,039...38,924,129

GAD1

glutamate decarboxylase 1

NCBI chr10:56,351,495...56,396,476
Ensembl chr10:56,353,253...56,396,524

glutamate ionotropic receptor AMPA type subunit 1

PMID:22072679 PMID:24201449 PMID:25716866 PMID:32717192

RGD:401976466 RGD:405096668 RGD:405100728 RGD:405101690

NCBI chr23:55,944,128...56,265,748
Ensembl chr23:56,101,294...56,265,849

GRIN1

glutamate ionotropic receptor NMDA type subunit 1

acts_upstream_of_or_within

(PMID:18423864)

PMID:18423864

NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231

NCAM1

neural cell adhesion molecule 1

NCBI chr 1:104,332,622...104,647,258

NPY1R

neuropeptide Y receptor Y1

NCBI chr 7:109,774,700...109,794,543
Ensembl chr 7:109,774,918...109,776,905

PPP1R1B

protein phosphatase 1 regulatory inhibitor subunit 1B

acts_upstream_of_or_within

(PMID:18496528)

PMID:18496528

NCBI chr16:66,530,640...66,541,025
Ensembl chr16:66,530,488...66,541,242

PPP2R2A

protein phosphatase 2 regulatory subunit Balpha

involved_in
acts_upstream_of_or_within

(PMID:16102737)

PMID:16102737

GO_REF:0000107

NCBI chr 8:24,390,751...24,485,657
Ensembl chr 8:24,390,781...24,487,195

PPP5C

protein phosphatase 5 catalytic subunit

acts_upstream_of_or_within

(PMID:16102737)

PMID:16102737

NCBI chr 6:39,726,627...39,767,467
Ensembl chr 6:39,726,623...39,767,464

PRKCE

protein kinase C epsilon

involved_in
acts_upstream_of_or_within

(PMID:16899053)

PMID:16899053

GO_REF:0000107

NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343

PRKCG

protein kinase C gamma

involved_in

(MGI:3760696|PMID:11246146)

PMID:11246146

MGI:3760696

NCBI chr 6:46,574,560...46,600,329
Ensembl chr 6:46,575,439...46,600,364

solute carrier family 1 member 1

involved_in

(PMID:28049029)

PMID:28049029

NCBI chr12:74,949,560...75,041,455
Ensembl chr12:74,949,028...75,041,369

response to norepinephrine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COL1A2

collagen type I alpha 2 chain

NCBI chr21:54,602,780...54,639,832
Ensembl chr21:54,602,398...54,632,780

early growth response 1

NCBI chr23:41,139,636...41,143,598
Ensembl chr23:41,140,065...41,142,374

glycerol kinase

NCBI chr X:29,043,390...29,119,516
Ensembl chr X:29,043,571...29,118,646

nuclear receptor subfamily 1 group H member 4

NCBI chr11:95,792,428...95,877,989
Ensembl chr11:95,792,996...95,878,293

PPARG coactivator 1 alpha

in brown adipose tissue

PMID:23443926

RGD:7241822

NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582

RNLS

renalase, FAD dependent amine oxidase

acts_upstream_of_or_within

(PMID:21178975)

PMID:21178975

NCBI chr 9:81,725,115...82,029,361

response to phenylpropanoid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BCL2 apoptosis regulator

17-methoxyl-7-hydroxy-benzene-furanchalcone

PMID:22700048

RGD:11522761

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

catalase

NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592

CEBPA

CCAAT enhancer binding protein alpha

NCBI chr 6:28,342,506...28,345,759
Ensembl chr 6:28,343,907...28,344,977

response to polycyclic arene

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

NCBI chr 8:114,113,780...114,232,656
Ensembl chr 8:114,113,778...114,195,956

response to progesterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

ABHD2

abhydrolase domain containing 2, acylglycerol lipase

involved_in

GO_REF:0000107

NCBI chr29:7,631,436...7,742,209
Ensembl chr29:7,631,412...7,740,394

adrenoceptor beta 2

NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401

aldehyde dehydrogenase 2 family member

NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374

BCL2 associated agonist of cell death

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

complement C3

NCBI chr 6:6,250,422...6,289,264

CAV1

caveolin 1

acts_upstream_of_or_within
involved_in

(PMID:12388746)

PMID:12388746

GO_REF:0000107

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

C-C motif chemokine ligand 2

NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416

cyclin E1

NCBI chr 6:24,879,923...24,888,985

CD38 molecule

NCBI chr27:34,375,859...34,449,131
Ensembl chr27:34,376,271...34,449,425

claudin 4

NCBI chr28:9,242,054...9,244,972
Ensembl chr28:9,242,909...9,243,538

desmoglein 1

NCBI chr18:49,372,261...49,408,818
Ensembl chr18:49,375,262...49,406,742

desmoglein 2

NCBI chr18:49,174,539...49,227,519
Ensembl chr18:49,174,409...49,227,347

ERBB2

erb-b2 receptor tyrosine kinase 2

NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952

ERBB4

erb-b2 receptor tyrosine kinase 4

NCBI chr10:97,099,090...98,281,697

ERBB receptor feedback inhibitor 1

acts_upstream_of_or_within

(PMID:20018910)
(PMID:25976672)
(PMID:28925396), (PMID:29843645)

PMID:20018910 PMID:25976672 PMID:28925396 PMID:29843645

NCBI chr20:123,738,971...123,753,575
Ensembl chr20:123,738,973...123,755,809

Fos proto-oncogene, AP-1 transcription factor subunit

NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514

FosB proto-oncogene, AP-1 transcription factor subunit

PMID:11750070 PMID:12080023

RGD:2293785 RGD:2293786

NCBI chr 6:38,916,039...38,924,129

FOS like 1, AP-1 transcription factor subunit

NCBI chr 1:8,356,263...8,365,606
Ensembl chr 1:8,356,836...8,364,918

FOS like 2, AP-1 transcription factor subunit

NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373

GABRB1

gamma-aminobutyric acid type A receptor subunit beta1

NCBI chr27:2,829,385...3,254,292
Ensembl chr27:2,832,450...3,217,326

GAD1

glutamate decarboxylase 1

NCBI chr10:56,351,495...56,396,476
Ensembl chr10:56,353,253...56,396,524

GAD2

glutamate decarboxylase 2

NCBI chr 9:25,906,047...25,993,715
Ensembl chr 9:25,906,103...25,995,489

GJB2

gap junction protein beta 2

PMID:8612484 PMID:10342836

RGD:11568660 RGD:7349386

NCBI chr 3:801,786...808,165
Ensembl chr 3:807,379...808,059

GPI

glucose-6-phosphate isomerase

NCBI chr 6:29,404,067...29,451,290
Ensembl chr 6:29,403,500...29,453,162

HSPA8

heat shock protein family A (Hsp70) member 8

NCBI chr 1:114,447,348...114,452,693
Ensembl chr 1:114,446,544...114,451,562

JunB proto-oncogene, AP-1 transcription factor subunit

NCBI chr 6:11,479,108...11,480,942
Ensembl chr 6:11,479,407...11,480,450

mucin-4

NCBI chr15:91,313,060...91,345,172

LOC103245755

WW domain-binding protein 2-like

involved_in

GO_REF:0000107

NCBI chr26:40,120,432...40,122,225

MAP2

microtubule associated protein 2

NCBI chr10:95,319,649...95,431,106
Ensembl chr10:95,349,157...95,431,320

myelin basic protein

NCBI chr18:2,844,154...2,996,640
Ensembl chr18:2,868,795...2,997,046

macrophage migration inhibitory factor

NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757

NCF2

neutrophil cytosolic factor 2

NCBI chr25:45,770,370...45,807,064
Ensembl chr25:45,770,641...45,806,515

NCOA1

nuclear receptor coactivator 1

NCBI chr14:82,898,368...83,028,137
Ensembl chr14:82,897,348...83,013,589

NCOA2

nuclear receptor coactivator 2

involved_in
acts_upstream_of_or_within

(PMID:24571987)

PMID:24571987

GO_REF:0000107

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

NK2 homeobox 2

NCBI chr 2:50,499,802...50,511,309
Ensembl chr 2:50,500,691...50,502,438

NR1H3

nuclear receptor subfamily 1 group H member 3

involved_in

GO_REF:0000107

NCBI chr 1:18,041,495...18,061,196
Ensembl chr 1:18,041,830...18,051,501

neuregulin 1

NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487

oxytocin/neurophysin I prepropeptide

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

oxytocin receptor

NCBI chr22:44,746,108...44,764,501
Ensembl chr22:44,742,419...44,763,243

pyridoxal kinase

NCBI chr 2:87,489,249...87,534,376
Ensembl chr 2:87,489,315...87,531,621

progesterone receptor

NCBI chr 1:92,420,970...92,519,128
Ensembl chr 1:92,430,453...92,517,296

phosphoinositide-3-kinase regulatory subunit 1

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

PTGER2

prostaglandin E receptor 2

involved_in

(MGI:5619494|PMID:10684792)

CACAO

PMID:10684792

MGI:5619494

NCBI chr24:29,395,799...29,410,723
Ensembl chr24:29,396,464...29,409,575

PTGER3

prostaglandin E receptor 3

NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959

PTGER4

prostaglandin E receptor 4

NCBI chr 4:39,440,697...39,453,983
Ensembl chr 4:39,440,276...39,454,004

pleiotrophin

NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215

RAMP2

receptor activity modifying protein 2

NCBI chr16:63,526,915...63,529,697
Ensembl chr16:63,526,305...63,528,767

RELA proto-oncogene, NF-kB subunit

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

reelin

NCBI chr21:72,440,988...72,951,173
Ensembl chr21:72,440,160...72,950,747

SOCS1

suppressor of cytokine signaling 1

NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991

suppressor of cytokine signaling 3

NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423

sphingosine kinase 1

NCBI chr16:45,290,147...45,295,175
Ensembl chr16:45,290,421...45,293,128

SREBF1

sterol regulatory element binding transcription factor 1

NCBI chr16:16,847,603...16,874,239
Ensembl chr16:16,845,491...16,859,554

TACR1

tachykinin receptor 1

NCBI chr14:32,080,319...32,236,556
Ensembl chr14:32,083,615...32,233,596

transforming growth factor beta 1

involved_in

GO_REF:0000107

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

TGFB2

transforming growth factor beta 2

involved_in

GO_REF:0000107

NCBI chr25:11,163,651...11,259,868
Ensembl chr25:11,163,100...11,258,470

TGFB3

transforming growth factor beta 3

involved_in

GO_REF:0000107

NCBI chr24:53,203,593...53,227,483
Ensembl chr24:53,203,301...53,227,325

toll like receptor 2

NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795

toll like receptor 4

NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515

translocator protein

NCBI chr19:25,678,602...25,690,556
Ensembl chr19:25,686,981...25,690,768

TXNIP

thioredoxin interacting protein

NCBI chr20:12,756,145...12,759,853
Ensembl chr20:12,756,053...12,761,177

thymidylate synthetase

medroxyprogesterone acetate

PMID:9635926

RGD:2315839

NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856

ubiquitin protein ligase E3A

involved_in

(PMID:16772533)

PMID:16772533

NCBI chr26:56,638,936...56,738,555
Ensembl chr26:56,666,162...56,736,737

vascular endothelial growth factor A

NCBI chr17:28,377,959...28,394,508

WBP2

WW domain binding protein 2

involved_in

GO_REF:0000107

NCBI chr16:45,821,875...45,836,558
Ensembl chr16:45,821,967...45,835,530

YAP1

Yes1 associated transcriptional regulator

involved_in

(PMID:16772533)

PMID:16772533

NCBI chr 1:93,479,478...93,605,340
Ensembl chr 1:93,479,135...93,606,808

response to proline

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

NCBI chr 9:88,921,826...89,034,418
Ensembl chr 9:88,922,007...89,032,880

response to purine-containing compound

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

acetoacetyl-CoA synthetase

4-aminopyrazolopyrimidine

PMID:6501306

RGD:2301028

NCBI chr11:120,422,138...120,502,200
Ensembl chr11:120,422,232...120,502,271

ADA

adenosine deaminase

involved_in

(PMID:25644539)

NCBI chr 2:19,167,209...19,200,233

ADORA1

adenosine A1 receptor

involved_in

(PMID:25644539)

NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776

ADORA2A

adenosine A2a receptor

involved_in

GO_REF:0000107

NCBI chr19:7,691,678...7,706,781
Ensembl chr19:7,691,536...7,706,926

ADSS2

adenylosuccinate synthase 2

NCBI chr25:81,441,792...81,485,344
Ensembl chr25:81,442,787...81,485,292

ATF1

activating transcription factor 1

involved_in

GO_REF:0000107

NCBI chr11:46,992,068...47,049,142
Ensembl chr11:47,003,621...47,049,381

cyclin E1

NCBI chr 6:24,879,923...24,888,985

cAMP responsive element binding protein 1

involved_in

(PMID:25644539)

NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832

hypoxia inducible factor 1 subunit alpha

adenosine, inosine

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

3-hydroxy-3-methylglutaryl-CoA synthase 1

4-aminopyrazolopyrimidine

PMID:16260

RGD:2302235

NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409

solute carrier family 6 member 1

NCBI chr22:47,033,436...47,076,785
Ensembl chr22:47,033,467...47,078,844

TRPM2

transient receptor potential cation channel subfamily M member 2

involved_in

(PMID:19171771)

PMID:19171771

NCBI chr 2:88,082,391...88,170,340
Ensembl chr 2:88,087,448...88,170,344

response to rapamycin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

forkhead box P3

NCBI chr X:46,349,890...46,365,133

HNRNPD

heterogeneous nuclear ribonucleoprotein D

NCBI chr 7:30,729,697...30,749,793
Ensembl chr 7:30,731,175...30,749,876

LIPA

lipase A, lysosomal acid type

involved_in
acts_upstream_of_or_within

(PMID:25807535)

PMID:25807535

GO_REF:0000107

NCBI chr 9:82,639,220...82,677,479
Ensembl chr 9:82,638,621...82,677,488

response to resveratrol

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP5F1D

ATP synthase F1 subunit delta

NCBI chr 6:1,010,210...1,013,360
Ensembl chr 6:1,010,265...1,013,002

G6PC1

glucose-6-phosphatase catalytic subunit 1

NCBI chr16:63,380,921...63,392,122
Ensembl chr16:63,381,382...63,391,540

heat shock protein family D (Hsp60) member 1

NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363

insulin receptor

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

potassium inwardly rectifying channel subfamily J member 11

involved_in
acts_upstream_of_or_within

(PMID:24498880)

PMID:24498880

GO_REF:0000107

NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801

KCNJ8

potassium inwardly rectifying channel subfamily J member 8

involved_in
acts_upstream_of_or_within

(PMID:24498880)

PMID:24498880

GO_REF:0000107

NCBI chr11:21,624,963...21,634,940
Ensembl chr11:21,624,970...21,634,042

sirtuin 1

PMID:23555824 PMID:23747682

RGD:10047117 RGD:10047126

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

response to rotenone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KIF1B

kinesin family member 1B

NCBI chr20:121,393,478...121,567,704
Ensembl chr20:121,395,836...121,546,803

KIF5A

kinesin family member 5A

NCBI chr11:53,458,795...53,493,801

response to salicylic acid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GPX2

glutathione peroxidase 2

NCBI chr24:42,151,205...42,155,335

SLC26A5

solute carrier family 26 member 5

NCBI chr21:72,347,276...72,418,311
Ensembl chr21:72,347,792...72,393,765

response to steroid hormone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCA2

ATP binding cassette subfamily A member 2

involved_in

(PMID:15238223)

PMID:15238223

NCBI chr12:1,161,340...1,183,807
Ensembl chr12:1,162,865...1,183,113

ATP binding cassette subfamily C member 2

NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265

ACAA1

acetyl-CoA acyltransferase 1

NCBI chr15:1,282,556...1,297,154
Ensembl chr15:1,282,650...1,297,832

acrosin

NCBI chr19:33,231,521...33,236,141

ACSL6

acyl-CoA synthetase long chain family member 6

NCBI chr23:34,787,097...34,846,387
Ensembl chr23:34,787,432...34,829,042

ACTA1

actin alpha 1, skeletal muscle

NCBI chr25:66,700,448...66,703,325
Ensembl chr25:66,700,369...66,714,891

ADRA1B

adrenoceptor alpha 1B

NCBI chr23:62,281,500...62,338,290

arginase 1

prednisolone

NCBI chr13:41,971,955...41,983,372
Ensembl chr13:41,971,802...41,983,049

argininosuccinate lyase

NCBI chr28:1,782,434...1,800,581
Ensembl chr28:1,782,553...1,802,517

argininosuccinate synthase 1

NCBI chr12:7,643,484...7,701,334

axin 2

NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281

BCL2 apoptosis regulator

acts_upstream_of_or_within

(PMID:8170972)

PMID:8170972

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

carbonic anhydrase 2

NCBI chr 8:80,830,963...80,848,245
Ensembl chr 8:80,830,939...80,848,707

carbonic anhydrase 4

NCBI chr16:31,369,238...31,379,366

CCKAR

cholecystokinin A receptor

NCBI chr27:23,855,766...23,866,104
Ensembl chr27:23,856,705...23,865,367

cyclin D1

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

cyclin E1

NCBI chr 6:24,879,923...24,888,985

collagen type I alpha 1 chain

nandrolone decanoate

NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930

carbamoyl-phosphate synthase 1

prednisolone

NCBI chr10:96,267,890...96,392,393
Ensembl chr10:96,267,889...96,392,206

cytochrome P450 family 11 subfamily A member 1

dehydroepiandrosterone

NCBI chr26:9,122,008...9,151,844

CYP17A1

cytochrome P450 family 17 subfamily A member 1

dehydroepiandrosterone

NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180

cytochrome P450 family 1 subfamily B member 1

dehydroepiandrosterone

PMID:12704664

RGD:7829755

NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157

DAB2

DAB adaptor protein 2

NCBI chr 4:38,171,320...38,224,275
Ensembl chr 4:38,173,026...38,224,231

dopamine receptor D1

nandrolone decanoate

NCBI chr23:77,587,340...77,591,434

dopamine receptor D4

nandrolone decanoate

NCBI chr 1:454,018...459,582

ERBB receptor feedback inhibitor 1

acts_upstream_of_or_within

(PMID:19439667)

PMID:19439667

NCBI chr20:123,738,971...123,753,575
Ensembl chr20:123,738,973...123,755,809

Fos proto-oncogene, AP-1 transcription factor subunit

pregnenolone sulfate

NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514

GC vitamin D binding protein

NCBI chr 7:20,254,604...20,298,384
Ensembl chr 7:20,253,879...20,298,265

GNRH1

gonadotropin releasing hormone 1

involved_in
acts_upstream_of_or_within

(PMID:17332066)

PMID:17332066

GO_REF:0000107

NCBI chr 8:23,543,717...23,550,728
Ensembl chr 8:23,542,806...23,547,771

HMGB2

high mobility group box 2

acts_upstream_of_or_within

(PMID:11262228)

PMID:11262228

NCBI chr 7:119,440,089...119,442,806
Ensembl chr 7:119,440,468...119,443,578

HSD11B2

hydroxysteroid 11-beta dehydrogenase 2

NCBI chr 5:60,017,967...60,040,959
Ensembl chr 5:60,019,434...60,025,353

hydroxysteroid 17-beta dehydrogenase 3

dehydroepiandrosterone

NCBI chr12:106,831,807...106,885,543
Ensembl chr12:106,832,034...106,886,385

HSD17B4

hydroxysteroid 17-beta dehydrogenase 4

testosterone-enanthate

PMID:25603467

RGD:10411879

NCBI chr23:22,674,059...22,761,270
Ensembl chr23:22,674,072...22,762,056

IDH1

isocitrate dehydrogenase (NADP(+)) 1

NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975

insulin like growth factor 1

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

insulin like growth factor binding protein 2

NCBI chr10:102,469,611...102,503,229
Ensembl chr10:102,469,669...102,503,276

JUN

Jun proto-oncogene, AP-1 transcription factor subunit

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

LOC103236010

alcohol dehydrogenase 1C

involved_in

GO_REF:0000107

NCBI chr 7:47,480,809...47,526,508

lysyl oxidase

NCBI chr23:25,158,458...25,172,763
Ensembl chr23:25,157,269...25,172,757

monoamine oxidase B

nandrolone decanoate

NCBI chr X:40,936,789...41,054,547
Ensembl chr X:40,936,711...41,054,641

MAPK8

mitogen-activated protein kinase 8

NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425

MDM2 proto-oncogene

pregnenolone

NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890

OGA

O-GlcNAcase

Deoxycorticosterone acetate

PMID:19139380

RGD:2305938

NCBI chr 9:94,812,126...94,847,118

oxytocin/neurophysin I prepropeptide

allopregnanolone

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

oxytocin receptor

allopregnanolone

NCBI chr22:44,746,108...44,764,501
Ensembl chr22:44,742,419...44,763,243

PAQR7

progestin and adipoQ receptor family member 7

involved_in

GO_REF:0000118

NCBI chr20:106,897,141...106,909,225
Ensembl chr20:106,908,063...106,909,118

PAQR8

progestin and adipoQ receptor family member 8

involved_in

GO_REF:0000118

NCBI chr17:20,096,407...20,142,477
Ensembl chr17:20,099,906...20,100,970

protein phosphatase 1 regulatory subunit 9B

estradiol and progesterone

PMID:20399784

RGD:10043792

NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680

RBBP7

RB binding protein 7, chromatin remodeling factor

NCBI chr X:15,268,650...15,294,648
Ensembl chr X:15,269,026...15,294,592

SERPINA7

serpin family A member 7

NCBI chr X:93,895,103...93,899,718
Ensembl chr X:93,894,788...93,898,738

secreted phosphoprotein 1

NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407

steroid 5 alpha-reductase 2

NCBI chr14:75,915,495...75,971,280
Ensembl chr14:75,917,260...75,970,365

somatostatin

NCBI chr15:81,946,287...81,947,775
Ensembl chr15:81,946,206...81,947,790

steroidogenic acute regulatory protein

dehydroepiandrosterone

NCBI chr 8:36,164,891...36,174,424
Ensembl chr 8:36,167,694...36,174,583

TBL1X

transducin beta like 1 X-linked

acts_upstream_of_or_within

(PMID:14980219)

PMID:14980219

NCBI chr X:7,921,674...8,173,139
Ensembl chr X:8,091,125...8,173,679

TGFBR2

transforming growth factor beta receptor 2

NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711

tyrosine hydroxylase

NCBI chr 1:1,969,194...1,977,263
Ensembl chr 1:1,966,460...1,977,218

uncoupling protein 3

NCBI chr 1:65,269,611...65,279,079
Ensembl chr 1:65,269,607...65,278,807

response to stilbenoid

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APOA4

apolipoprotein A4

involved_in

GO_REF:0000107

NCBI chr 1:108,186,627...108,190,508
Ensembl chr 1:108,186,921...108,189,698

CD36

CD36 molecule (CD36 blood group)

involved_in

GO_REF:0000107

NCBI chr21:68,214,875...68,309,336
Ensembl chr21:68,216,201...68,268,669

CIDEA

cell death inducing DFFA like effector a

involved_in

(MGI:4943399|PMID:17086191)

NCBI chr18:70,836,188...70,853,917

FGL1

fibrinogen like 1

involved_in

(MGI:4943399|PMID:17086191)

NCBI chr 8:15,962,625...16,016,118
Ensembl chr 8:15,962,053...15,982,336

IDI1

isopentenyl-diphosphate delta isomerase 1

involved_in

(MGI:4943399|PMID:17086191)

NCBI chr 9:995,608...1,011,226
Ensembl chr 9:996,909...1,003,963

IFIT3

interferon induced protein with tetratricopeptide repeats 3

involved_in

(MGI:4943399|PMID:17086191)

NCBI chr 9:82,738,747...82,750,134
Ensembl chr 9:82,743,001...82,751,309

interleukin 1 beta

resveratrol

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

LY6D

lymphocyte antigen 6 family member D

involved_in

GO_REF:0000107

NCBI chr 8:137,033,609...137,038,589

SLC22A7

solute carrier family 22 member 7

involved_in

(MGI:4943399|PMID:17086191)

NCBI chr17:28,848,115...28,856,298
Ensembl chr17:28,846,791...28,855,355

response to tacrolimus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CXCR4

C-X-C motif chemokine receptor 4

NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309

interferon gamma

NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473

interleukin 2

NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969

response to testosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adrenoceptor beta 2

NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401

adenylate kinase 1

NCBI chr12:10,251,793...10,261,635
Ensembl chr12:10,256,054...10,261,465

aldehyde dehydrogenase 2 family member

NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374

androgen receptor

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

arginine vasopressin

NCBI chr 2:33,761,066...33,764,608
Ensembl chr 2:33,761,140...33,763,172

BCL2 associated agonist of cell death

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

bone gamma-carboxyglutamate protein

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

bone morphogenetic protein 4

NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225

carbonic anhydrase 9

NCBI chr12:44,921,530...44,929,504
Ensembl chr12:44,921,665...44,928,831

CACNA1B

calcium voltage-gated channel subunit alpha1 B

NCBI chr12:75,441...335,980
Ensembl chr12:78,011...335,820

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914

calreticulin

NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792

caspase 6

NCBI chr 7:57,592,632...57,616,094
Ensembl chr 7:57,593,342...57,607,489

Cbl proto-oncogene

NCBI chr 1:110,581,049...110,679,284
Ensembl chr 1:110,581,143...110,674,481

cyclin D2

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

CDK4

cyclin dependent kinase 4

NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861

CFLAR

CASP8 and FADD like apoptosis regulator

NCBI chr10:86,768,252...86,819,963
Ensembl chr10:86,782,240...86,816,652

C-reactive protein

NCBI chr20:4,232,262...4,235,826
Ensembl chr20:4,232,913...4,235,377

CSNK2A1

casein kinase 2 alpha 1

NCBI chr 2:55,982,259...56,047,023

casein kinase 2 beta

NCBI chr17:40,354,520...40,359,136
Ensembl chr17:40,352,367...40,358,401

CYP19A1

cytochrome P450 family 19 subfamily A member 1

NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277

defensin beta 1

NCBI chr 8:6,643,753...6,652,209
Ensembl chr 8:6,643,556...6,651,699

DNA methyltransferase 1

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

dual specificity phosphatase 1

NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532

EDN1

endothelin 1

5alpha-dihydrotestosterone

PMID:20660069

RGD:4144839

NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198

erythropoietin

NCBI chr28:12,487,222...12,491,986
Ensembl chr28:12,489,766...12,491,908

estrogen receptor 2

PMID:16904920 PMID:23500659

RGD:1626504 RGD:7364973

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

FDPS

farnesyl diphosphate synthase

NCBI chr20:8,514,311...8,526,363

forkhead box P1

dihydrotestosterone

NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502

forkhead box P2

NCBI chr21:82,799,147...83,392,568
Ensembl chr21:83,129,308...83,389,483

GBA1

glucosylceramidase beta 1

dihydroxytestosterone

PMID:9101438

RGD:5508438

NCBI chr20:8,598,110...8,631,517
Ensembl chr20:8,598,628...8,630,990

GNRH1

gonadotropin releasing hormone 1

NCBI chr 8:23,543,717...23,550,728
Ensembl chr 8:23,542,806...23,547,771

GPI

glucose-6-phosphate isomerase

NCBI chr 6:29,404,067...29,451,290
Ensembl chr 6:29,403,500...29,453,162

GPT2

glutamic--pyruvic transaminase 2

NCBI chr 5:32,743,850...32,791,299
Ensembl chr 5:32,744,065...32,791,479

HAVCR1

hepatitis A virus cellular receptor 1

NCBI chr23:59,422,769...59,454,183
Ensembl chr23:59,423,334...59,453,531

3-hydroxy-3-methylglutaryl-CoA synthase 2

NCBI chr20:14,018,669...14,040,934
Ensembl chr20:14,019,692...14,041,016

homeobox A10

NCBI chr21:31,189,240...31,198,244

homeobox A11

NCBI chr21:31,180,232...31,187,709
Ensembl chr21:31,183,682...31,186,010

homeobox A13

NCBI chr21:31,168,239...31,175,960
Ensembl chr21:31,168,793...31,173,056

homeobox A9

NCBI chr21:31,199,573...31,206,455
Ensembl chr21:31,203,422...31,206,433

HOXB13

homeobox B13

PMID:17138648 PMID:17218409

RGD:11354895 RGD:2314760

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

homeobox D13

NCBI chr10:61,662,670...61,670,955
Ensembl chr10:61,667,880...61,669,743

heat shock transcription factor 1

NCBI chr 8:138,503,836...138,529,562
Ensembl chr 8:138,503,831...138,529,165

insulin receptor

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

potassium inwardly rectifying channel subfamily J member 11

NCBI chr 1:47,582,519...47,586,466
Ensembl chr 1:47,583,629...47,584,801

LOC103233689

thromboxane A2 receptor

NCBI chr 6:3,354,358...3,365,779
Ensembl chr 6:3,355,314...3,359,761

LOC103236010

alcohol dehydrogenase 1C

involved_in

GO_REF:0000107

NCBI chr 7:47,480,809...47,526,508

LOC103242912

nucleoside diphosphate kinase A

5alpha-dihydrotestosterone

PMID:19639176

RGD:5132866

NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616

mitogen-activated protein kinase 1

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

mitofusin 2

NCBI chr20:119,787,700...119,818,455
Ensembl chr20:119,787,370...119,816,693

myostatin

NCBI chr10:75,564,816...75,570,956
Ensembl chr10:75,565,152...75,570,528

MTAP

methylthioadenosine phosphorylase

NCBI chr15:84,196,548...84,198,357
Ensembl chr12:57,997,427...58,050,241

NASP

nuclear autoantigenic sperm protein

NCBI chr20:87,180,440...87,215,418
Ensembl chr20:87,180,453...87,215,939

NKX3-1

NK3 homeobox 1

involved_in

(MGI:87385|PMID:9142502)

PMID:9142502

MGI:87385

NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319

NQO1

NAD(P)H quinone dehydrogenase 1

Testosterone propionate

PMID:31819135

RGD:25823186

NCBI chr 5:57,676,547...57,695,434
Ensembl chr 5:57,675,981...57,716,599

phosphodiesterase 5A

NCBI chr 7:66,826,316...66,955,220
Ensembl chr 7:66,826,315...66,955,036

protein inhibitor of activated STAT 2

NCBI chr18:33,967,894...34,075,824
Ensembl chr18:33,967,999...34,067,910

phosphoinositide-3-kinase regulatory subunit 1

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

phospholamban

NCBI chr13:55,316,962...55,332,502
Ensembl chr13:55,318,326...55,318,481

PSPH

phosphoserine phosphatase

NCBI chr21:2,728,490...2,761,805
Ensembl chr21:2,753,284...2,757,008

ribosomal protein S6 kinase B1

NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453

steroid 5 alpha-reductase 1

testosterone and dihydrotestosterone

PMID:16595696

RGD:4891918

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

steroid 5 alpha-reductase 2

testosterone and dihydrotestosterone

PMID:16595696

RGD:4891918

NCBI chr14:75,915,495...75,971,280
Ensembl chr14:75,917,260...75,970,365

thrombospondin 1

NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812

TPMT

thiopurine S-methyltransferase

NCBI chr17:53,987,561...54,012,647
Ensembl chr17:53,987,559...54,014,650

translocator protein

NCBI chr19:25,678,602...25,690,556
Ensembl chr19:25,686,981...25,690,768

urotensin 2

NCBI chr20:123,903,137...123,910,180

Wnt family member 5A

NCBI chr22:16,809,454...16,836,815
Ensembl chr22:16,809,451...16,825,048

XRN1

5'-3' exoribonuclease 1

NCBI chr15:48,174,262...48,310,527
Ensembl chr15:48,174,316...48,305,641

response to thyroxine

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

CRLS1

cardiolipin synthase 1

NCBI chr 2:32,094,610...32,127,186
Ensembl chr 2:32,091,519...32,127,170

coagulation factor VII

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

HSPA9

heat shock protein family A (Hsp70) member 9

NCBI chr23:41,230,675...41,251,177
Ensembl chr23:41,231,364...41,251,150

LOC103215401

arylamine N-acetyltransferase 1

NCBI chr 8:16,302,296...16,315,406
Ensembl chr 8:16,314,446...16,315,318

TOMM70

translocase of outer mitochondrial membrane 70

NCBI chr22:80,477,429...80,516,536
Ensembl chr22:80,477,872...80,516,670

thioredoxin

NCBI chr12:29,296,166...29,308,979

response to toluene

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYP2D6

cytochrome P450 family 2 subfamily D member 6

NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513

L1CAM

L1 cell adhesion molecule

NCBI chr X:128,285,128...128,309,173
Ensembl chr X:128,285,130...128,299,570

response to trichostatin A

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HNF4A

hepatocyte nuclear factor 4 alpha

NCBI chr 2:19,390,870...19,466,300
Ensembl chr 2:19,388,891...19,421,664

prolactin

NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631

response to vitamin B1

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ALAD

aminolevulinate dehydratase

NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845

translocator protein

NCBI chr19:25,678,602...25,690,556
Ensembl chr19:25,686,981...25,690,768

response to vitamin B2

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CEBPA

CCAAT enhancer binding protein alpha

NCBI chr 6:28,342,506...28,345,759
Ensembl chr 6:28,343,907...28,344,977

MTHFR

methylenetetrahydrofolate reductase

NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950

response to vitamin B6

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

alkaline phosphatase, biomineralization associated

involved_in

GO_REF:0000107

NCBI chr20:111,055,583...111,124,143
Ensembl chr20:111,055,558...111,081,850

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

(PMID:12082181)

PMID:12082181

NCBI chr13:41,670,416...41,755,549

KYNU

kynureninase

involved_in

(PMID:1939450)

PMID:1939450

NCBI chr10:28,230,129...28,394,103
Ensembl chr10:28,230,508...28,394,076

response to vitamin D

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

alkaline phosphatase, biomineralization associated

involved_in

GO_REF:0000107

NCBI chr20:111,055,583...111,124,143
Ensembl chr20:111,055,558...111,081,850

bone gamma-carboxyglutamate protein

involved_in

GO_REF:0000107

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

BMP7

bone morphogenetic protein 7

NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944

CD4 molecule

NCBI chr11:6,824,797...6,856,440
Ensembl chr11:6,825,245...6,853,852

CDKN2D

cyclin dependent kinase inhibitor 2D

involved_in

(PMID:16322758)

PMID:16322758

NCBI chr 6:9,579,648...9,582,249
Ensembl chr 6:9,579,470...9,582,101

crystallin mu

NCBI chr 5:19,388,842...19,409,230
Ensembl chr 5:19,388,841...19,409,199

CXCL10

C-X-C motif chemokine ligand 10

NCBI chr 7:24,526,657...24,529,193
Ensembl chr 7:24,526,680...24,529,130

CYP24A1

cytochrome P450 family 24 subfamily A member 1

involved_in

GO_REF:0000107

NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884

CYP27B1

cytochrome P450 family 27 subfamily B member 1

involved_in

PMID:3000565

GO_REF:0000107 RGD:2307325

NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443

ERBB2

erb-b2 receptor tyrosine kinase 2

NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952

ERBB4

erb-b2 receptor tyrosine kinase 4

NCBI chr10:97,099,090...98,281,697

GGCX

gamma-glutamyl carboxylase

NCBI chr14:21,593,202...21,605,800
Ensembl chr14:21,593,088...21,604,885

interleukin 1 beta

NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729

INSR

insulin receptor

1,25-dihydroxyvitamin D3, in diabetic rats

PMID:18638371

RGD:2307025

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

klotho

NCBI chr 3:11,755,015...11,799,537
Ensembl chr 3:11,755,016...11,797,596

LRP2

LDL receptor related protein 2

NCBI chr10:54,672,876...54,889,374
Ensembl chr10:54,711,517...54,889,208

neuregulin 1

NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487

PHEX

phosphate regulating endopeptidase X-linked

NCBI chr X:20,507,619...20,733,367
Ensembl chr X:20,522,498...20,734,599

PLA2G4A

phospholipase A2 group IVA

NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431

PRKCB

protein kinase C beta

NCBI chr 5:21,558,608...21,940,536
Ensembl chr 5:21,558,441...21,943,864

prostaglandin-endoperoxide synthase 2

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

parathyroid hormone

NCBI chr 1:51,327,555...51,330,810

retinoid X receptor alpha

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

SERPINH1

serpin family H member 1

NCBI chr 1:66,787,978...66,798,930
Ensembl chr 1:66,788,240...66,799,072

SLC8A2

solute carrier family 8 member A2

NCBI chr 6:40,758,106...40,803,277
Ensembl chr 6:40,757,440...40,797,126

secreted phosphoprotein 1

involved_in

(PMID:16720713)

PMID:16720713

NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407

stanniocalcin 1

NCBI chr 8:21,975,286...21,988,182
Ensembl chr 8:21,975,283...21,988,198

stanniocalcin 2

NCBI chr23:75,475,020...75,489,727
Ensembl chr23:75,475,022...75,488,678

transforming growth factor beta 1

PMID:11956143 PMID:24613393

RGD:11073674 RGD:2302111

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

TGFB2

transforming growth factor beta 2

NCBI chr25:11,163,651...11,259,868
Ensembl chr25:11,163,100...11,258,470

TPCN2

two pore segment channel 2

NCBI chr 1:5,491,476...5,529,015
Ensembl chr 1:5,490,910...5,528,718

TRIM25

tripartite motif containing 25

NCBI chr16:36,496,829...36,522,427
Ensembl chr16:36,496,772...36,524,148

tyrosinase

NCBI chr 1:80,330,051...80,444,646

vimentin

NCBI chr 9:17,183,466...17,191,771
Ensembl chr 9:17,183,388...17,191,829

response to vitamin E

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

adenosine deaminase

NCBI chr 2:19,167,209...19,200,233

ALAD

aminolevulinate dehydratase

in lead-treated rats

NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845

arginase 1

NCBI chr13:41,971,955...41,983,372
Ensembl chr13:41,971,802...41,983,049

arginase 2

NCBI chr24:44,851,139...44,884,118
Ensembl chr24:44,851,175...44,883,853

BCL2 apoptosis regulator

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

beclin 1

NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322

CAT

catalase

PMID:19641679 PMID:19914224

RGD:5130868 RGD:9068475

NCBI chr 1:30,792,533...30,828,920
Ensembl chr 1:30,792,399...30,829,592

cyclin D1

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

cyclin E1

NCBI chr 6:24,879,923...24,888,985

cytochrome P450 family 11 subfamily A member 1

in PCB-treated rats

NCBI chr26:9,122,008...9,151,844

CYP1A2

cytochrome P450 family 1 subfamily A member 2

NCBI chr26:8,727,996...8,733,254

EIF2AK2

eukaryotic translation initiation factor 2 alpha kinase 2

NCBI chr14:70,246,081...70,290,851
Ensembl chr14:70,247,168...70,296,463

FKBP1B

FKBP prolyl isomerase 1B

NCBI chr14:83,606,511...83,620,289
Ensembl chr14:83,606,454...83,620,205

glutathione peroxidase 1

NCBI chr22:10,754,976...10,756,617

3-hydroxy-3-methylglutaryl-CoA synthase 1

NCBI chr 4:42,083,523...42,107,410
Ensembl chr 4:42,080,949...42,107,409

hydroxysteroid 17-beta dehydrogenase 3

in PCB-treated rats

NCBI chr12:106,831,807...106,885,543
Ensembl chr12:106,832,034...106,886,385

insulin like growth factor 1 receptor

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

leptin

NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220

LOC103218970

alpha-1-acid glycoprotein 1

NCBI chr12:25,257,002...25,261,255
Ensembl chr12:25,256,969...25,260,446

MEF2C

myocyte enhancer factor 2C

NCBI chr 4:82,702,378...82,887,491
Ensembl chr 4:82,706,738...82,788,152

macrophage migration inhibitory factor

NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757

NOS1

nitric oxide synthase 1

NCBI chr11:112,642,374...112,673,882

SRSF2

serine and arginine rich splicing factor 2

NCBI chr16:44,945,193...44,948,496
Ensembl chr16:44,945,200...44,946,438

serotonin receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G protein-coupled estrogen receptor 1

NCBI chr28:20,491,874...20,497,966
Ensembl chr28:20,492,188...20,493,315

HTR1A

5-hydroxytryptamine receptor 1A

involved_in

PMID:11927181 PMID:12149253

GO_REF:0000107 RGD:2303632 RGD:730812

NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212

HTR3A

5-hydroxytryptamine receptor 3A

involved_in

GO_REF:0000107

NCBI chr 1:105,359,139...105,375,217
Ensembl chr 1:105,359,730...105,374,664

HTR3B

5-hydroxytryptamine receptor 3B

involved_in
acts_upstream_of_or_within

(MGI:1859688|PMID:10854267)

Ensembl
GOC

PMID:10854267

GO_REF:0000107 MGI:1859688

NCBI chr 1:105,287,738...105,328,793
Ensembl chr 1:105,288,865...105,328,714

HTR3D

5-hydroxytryptamine receptor 3D pseudogene

involved_in

(PMID:17392525)

ComplexPortal

PMID:17392525

NCBI chr15:5,385,897...5,390,378

HTR3D

5-hydroxytryptamine receptor 3D

involved_in

GO_REF:0000107

Ensembl chr15:5,387,328...5,393,468

HTR3E

5-hydroxytryptamine receptor 3E

involved_in

GO_REF:0000108

NCBI chr15:5,314,837...5,324,086

HTR7

5-hydroxytryptamine receptor 7

NCBI chr 9:84,081,713...84,191,112
Ensembl chr 9:84,083,396...84,190,876

LOC103221320

5-hydroxytryptamine receptor 3C

involved_in

GO_REF:0000108

NCBI chr15:5,367,858...5,375,095

ZACN

zinc activated ion channel

involved_in

GO_REF:0000108

NCBI chr16:45,594,929...45,598,899
Ensembl chr16:45,595,041...45,598,375

SREBP-SCAP complex retention in endoplasmic reticulum

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

INSIG1

insulin induced gene 1

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr21:123,448,614...123,460,778
Ensembl chr21:123,449,106...123,460,807

INSIG2

insulin induced gene 2

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr10:12,198,390...12,219,002
Ensembl chr10:12,196,990...12,219,023

steroid hormone mediated signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABHD2

abhydrolase domain containing 2, acylglycerol lipase

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr29:7,631,436...7,742,209
Ensembl chr29:7,631,412...7,740,394

estrogen receptor 1

involved_in

GO_REF:0000002

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

G protein-coupled estrogen receptor 1

involved_in

GO_REF:0000107

NCBI chr28:20,491,874...20,497,966
Ensembl chr28:20,492,188...20,493,315

LOC103223491

peroxisome proliferator-activated receptor alpha

involved_in

GO_REF:0000108

NCBI chr19:28,614,892...28,709,272
Ensembl chr19:28,615,413...28,708,763

LOC103247947

olfactory receptor 51E2

involved_in

(PMID:19389702)

PMID:19389702

NCBI chr 1:62,172,573...62,180,085
Ensembl chr 1:62,177,553...62,178,515

mitogen-activated protein kinase 1

involved_in

GO_REF:0000107

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

PAQR7

progestin and adipoQ receptor family member 7

involved_in

GO_REF:0000108

NCBI chr20:106,897,141...106,909,225
Ensembl chr20:106,908,063...106,909,118

PAQR8

progestin and adipoQ receptor family member 8

involved_in

GO_REF:0000108

NCBI chr17:20,096,407...20,142,477
Ensembl chr17:20,099,906...20,100,970

progesterone receptor

involved_in

GO_REF:0000002

NCBI chr 1:92,420,970...92,519,128
Ensembl chr 1:92,430,453...92,517,296

retinoid X receptor alpha

involved_in

GO_REF:0000108

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

RXRB

retinoid X receptor beta

involved_in

GO_REF:0000108

NCBI chr17:38,874,467...38,881,527
Ensembl chr17:38,874,681...38,881,653

RXRG

retinoid X receptor gamma

involved_in

GO_REF:0000108

NCBI chr25:63,444,128...63,490,594
Ensembl chr25:63,443,944...63,490,635

ZDHHC7

zinc finger DHHC-type palmitoyltransferase 7

involved_in

GO_REF:0000107

NCBI chr 5:70,379,228...70,419,885
Ensembl chr 5:70,379,179...70,401,139

vitamin D receptor signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PIM1

Pim-1 proto-oncogene, serine/threonine kinase

involved_in

GO_REF:0000107

NCBI chr17:34,968,661...34,973,920
Ensembl chr17:34,968,429...34,973,760

VDR

vitamin D receptor

involved_in